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Gene Expression Literature Summary
Symbol
Name
ID
Prickle2
prickle planar cell polarity protein 2
MGI:1925144

21 matching records from 21 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1 E2 E2.5 E3 E3.5 E7.5 E8 E9 E10.5 E11.5 E12.5 E13.5 E14.5 E15.5 E16.5 E17.5 E18.5 P
Immunohistochemistry (section) 1 2 1 1 1 1 1 4 3
In situ RNA (section) 1 1 1 2 2 1 1 2
Immunohistochemistry (whole mount) 1 1 1 1 1 2
In situ RNA (whole mount) 1 3 1 2
Western blot 1 1 1
RT-PCR 1 1 1 1 2 1 1
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Prickle2  prickle planar cell polarity protein 2   (Synonyms: 6230400G14Rik, 6720451F06Rik, mpk2)
Results  Reference
2J:157938 Antic D, Stubbs JL, Suyama K, Kintner C, Scott MP, Axelrod JD, Planar cell polarity enables posterior localization of nodal cilia and left-right axis determination during mouse and Xenopus embryogenesis. PLoS One. 2010;5(2):e8999
1*J:148410 Combes AN, Lesieur E, Harley VR, Sinclair AH, Little MH, Wilhelm D, Koopman P, Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development. Dev Dyn. 2009 May;238(5):1033-41
1J:201321 Copley CO, Duncan JS, Liu C, Cheng H, Deans MR, Postnatal refinement of auditory hair cell planar polarity deficits occurs in the absence of Vangl2. J Neurosci. 2013 Aug 28;33(35):14001-16
1J:269131 Cortijo C, Gouzi M, Tissir F, Grapin-Botton A, Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis. Cell Rep. 2012 Dec 27;2(6):1593-606
2*J:125765 Crompton LA, Du Roure C, Rodriguez TA, Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues. Dev Dyn. 2007 Nov;236(11):3137-43
9J:119451 Deans MR, Antic D, Suyama K, Scott MP, Axelrod JD, Goodrich LV, Asymmetric distribution of Prickle-like 2 reveals an early underlying polarization of vestibular sensory epithelia in the inner ear. J Neurosci. 2007 Mar 21;27(12):3139-47
1J:242825 Fong KS, Hufnagel RB, Khadka VS, Corley MJ, Maunakea AK, Fogelgren B, Ahmed ZM, Lozanoff S, A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure. Dis Model Mech. 2016 May 01;9(5):585-96
1J:245765 Goodyear RJ, Lu X, Deans MR, Richardson GP, A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane. Development. 2017 Nov 01;144(21):3978-3989
4*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1J:253478 Jiang T, Kindt K, Wu DK, Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells. Elife. 2017 Mar 7;6
2J:240026 Minegishi K, Hashimoto M, Ajima R, Takaoka K, Shinohara K, Ikawa Y, Nishimura H, McMahon AP, Willert K, Okada Y, Sasaki H, Shi D, Fujimori T, Ohtsuka T, Igarashi Y, Yamaguchi TP, Shimono A, Shiratori H, Hamada H, A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking. Dev Cell. 2017 Mar 13;40(5):439-452.e4
6*J:126805 Okuda H, Miyata S, Mori Y, Tohyama M, Mouse Prickle1 and Prickle2 are expressed in postmitotic neurons and promote neurite outgrowth. FEBS Lett. 2007 Oct 2;581(24):4754-60
1J:169765 Shafer B, Onishi K, Lo C, Colakoglu G, Zou Y, Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance. Dev Cell. 2011 Feb 15;20(2):177-91
1J:279029 Smith P, Godde N, Rubio S, Tekeste M, Vladar EK, Axelrod JD, Henderson DJ, Milgrom-Hoffman M, Humbert PO, Hinck L, VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland. Sci Rep. 2019 May 8;9(1):7079
1J:261565 Stoller ML, Roman O Jr., Deans MR, Domineering non-autonomy in Vangl1;Vangl2 double mutants demonstrates intercellular PCP signaling in the vertebrate inner ear. Dev Biol. 2018 May 1;437(1):17-26
1*J:143778 Tamplin OJ, Cox BJ, Rossant J, Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Dev Biol. 2011 Dec 15;360(2):415-25
8J:183948 Tao H, Inoue K, Kiyonari H, Bassuk AG, Axelrod JD, Sasaki H, Aizawa S, Ueno N, Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis. Dev Biol. 2012 Apr 15;364(2):138-48
2J:151993 Tao H, Suzuki M, Kiyonari H, Abe T, Sasaoka T, Ueno N, Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14426-31
1J:171050 Thiagarajan RD, Georgas KM, Rumballe BA, Lesieur E, Chiu HS, Taylor D, Tang DT, Grimmond SM, Little MH, Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286
5*J:106092 Tissir F, Goffinet AM, Expression of planar cell polarity genes during development of the mouse CNS. Eur J Neurosci. 2006 Feb;23(3):597-607
1J:185311 Yin H, Copley CO, Goodrich LV, Deans MR, Comparison of phenotypes between different vangl2 mutants demonstrates dominant effects of the Looptail mutation during hair cell development. PLoS One. 2012;7(2):e31988

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last database update
09/08/2020
MGI 6.15
The Jackson Laboratory