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Gene Expression Literature Summary
Symbol
Name
ID
Elp3
elongator acetyltransferase complex subunit 3
MGI:1921445

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E8.5 E12.5 E14.5 E16 E16.5 P
Immunohistochemistry (section) 3 1
In situ RNA (section) 1 1 1 1
Western blot 1 1 2
RT-PCR 1 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Elp3  elongator acetyltransferase complex subunit 3   (Synonyms: 2610507P14Rik, KAT9)
Results  Reference
1J:145561 Chen YT, Hims MM, Shetty RS, Mull J, Liu L, Leyne M, Slaugenhaupt SA, Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP. Mol Cell Biol. 2009 Feb;29(3):736-44
2*J:150477 Creppe C, Malinouskaya L, Volvert ML, Gillard M, Close P, Malaise O, Laguesse S, Cornez I, Rahmouni S, Ormenese S, Belachew S, Malgrange B, Chapelle JP, Siebenlist U, Moonen G, Chariot A, Nguyen L, Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin. Cell. 2009 Feb 6;136(3):551-64
1J:312377 Even A, Morelli G, Turchetto S, Shilian M, Bail RL, Laguesse S, Krusy N, Brisker A, Brandis A, Inbar S, Chariot A, Saudou F, Dietrich P, Dragatsis I, Brone B, Broix L, Rigo JM, Weil M, Nguyen L, ATP-citrate lyase promotes axonal transport across species. Nat Commun. 2021 Oct 7;12(1):5878
5J:280869 Freeman S, Mateo Sanchez S, Pouyo R, Van Lerberghe PB, Hanon K, Thelen N, Thiry M, Morelli G, Van Hees L, Laguesse S, Chariot A, Nguyen L, Delacroix L, Malgrange B, Proteostasis is essential during cochlear development for neuron survival and hair cell polarity. EMBO Rep. 2019 Sep;20(9):e47097
1*J:273516 Laguesse S, Close P, Van Hees L, Chariot A, Malgrange B, Nguyen L, Loss of Elp3 Impairs the Acetylation and Distribution of Connexin-43 in the Developing Cerebral Cortex. Front Cell Neurosci. 2017;11:122
4J:240003 Laguesse S, Creppe C, Nedialkova DD, Prevot PP, Borgs L, Huysseune S, Franco B, Duysens G, Krusy N, Lee G, Thelen N, Thiry M, Close P, Chariot A, Malgrange B, Leidel SA, Godin JD, Nguyen L, A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis. Dev Cell. 2015 Dec 07;35(5):553-67
1*J:280803 Ma J, Zhang LQ, He ZX, He XX, Wang YJ, Jian YL, Wang X, Zhang BB, Su C, Lu J, Huang BQ, Zhang Y, Wang GY, Guo WX, Qiu DL, Mei L, Xiong WC, Zheng YW, Zhu XJ, Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin. PLoS Biol. 2019 Oct;17(10):e3000461
1J:237480 Naftelberg S, Abramovitch Z, Gluska S, Yannai S, Joshi Y, Donyo M, Ben-Yaakov K, Gradus T, Zonszain J, Farhy C, Ashery-Padan R, Perlson E, Ast G, Phosphatidylserine Ameliorates Neurodegenerative Symptoms and Enhances Axonal Transport in a Mouse Model of Familial Dysautonomia. PLoS Genet. 2016 Dec;12(12):e1006486

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory