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Gene Expression Literature Summary
Symbol
Name
ID
Ttc21b
tetratricopeptide repeat domain 21B
MGI:1920918

3 matching records from 3 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E8 E8.5 E9.5 E10.5
Immunohistochemistry (section) 1
In situ RNA (whole mount) 1 1 1
Western blot 1
RT-PCR 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Ttc21b  tetratricopeptide repeat domain 21B   (Synonyms: 2410066K11Rik, aln, line 158, Thm1)
Results  Reference
1J:147584 Patterson VL, Damrau C, Paudyal A, Reeve B, Grimes DT, Stewart ME, Williams DJ, Siggers P, Greenfield A, Murdoch JN, Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway. Hum Mol Genet. 2009 May 15;18(10):1719-39
2*J:154376 Stottmann RW, Tran PV, Turbe-Doan A, Beier DR, Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain. Dev Biol. 2009 Nov 1;335(1):166-78
3J:133725 Tran PV, Haycraft CJ, Besschetnova TY, Turbe-Doan A, Stottmann RW, Herron BJ, Chesebro AL, Qiu H, Scherz PJ, Shah JV, Yoder BK, Beier DR, THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia. Nat Genet. 2008 Apr;40(4):403-10

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory