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Gene Expression Literature Summary
Symbol
Name
ID
Hfe2
hemochromatosis type 2 (juvenile)
MGI:1916835

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E9.5 E10.5 E12.5 E14 E14.5 E17.5 E18 P
Immunohistochemistry (section) 1
In situ RNA (section) 1 1 1 3 2 3
In situ RNA (whole mount) 1 1
In situ reporter (knock in) 1
Northern blot 1
Western blot 1 2
RT-PCR 1 1 1 1 4
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Hfe2  hemochromatosis type 2 (juvenile)   (Synonyms: 2310035L15Rik, 5230400G09Rik, DL-M, hemojuvelin, HJV, Rgmc)
Results  Reference
1*J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
4J:160796 Lee DH, Zhou LJ, Zhou Z, Xie JX, Jung JU, Liu Y, Xi CX, Mei L, Xiong WC, Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. Blood. 2010 Apr 15;115(15):3136-45
3*J:127437 Metzger M, Conrad S, Alvarez-Bolado G, Skutella T, Just L, Gene expression of the repulsive guidance molecules during development of the mouse intestine. Dev Dyn. 2005 Sep;234(1):169-75
1J:176655 Moroishi T, Nishiyama M, Takeda Y, Iwai K, Nakayama KI, The FBXL5-IRP2 Axis Is Integral to Control of Iron Metabolism In Vivo. Cell Metab. 2011 Sep 7;14(3):339-51
3J:87768 Niederkofler V, Salie R, Sigrist M, Arber S, Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci. 2004 Jan 28;24(4):808-18
1J:89169 Oldekamp J, Kramer N, Alvarez-Bolado G, Skutella T, Expression pattern of the repulsive guidance molecules RGM A, B and C during mouse development. Gene Expr Patterns. 2004 May;4(3):283-8
2J:90082 Samad TA, Srinivasan A, Karchewski LA, Jeong SJ, Campagna JA, Ji RR, Fabrizio DA, Zhang Y, Lin HY, Bell E, Woolf CJ, DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J Neurosci. 2004 Feb 25;24(8):2027-36
6*J:87381 Schmidtmer J, Engelkamp D, Isolation and expression pattern of three mouse homologues of chick Rgm. Gene Expr Patterns. 2004 Jan;4(1):105-10
2J:127109 Schnichels S, Conrad S, Warstat K, Henke-Fahle S, Skutella T, Schraermeyer U, Julien S, Gene expression of the repulsive guidance molecules/neogenin in the developing and mature mouse visual system: C57BL/6J vs. the glaucoma model DBA/2J. Gene Expr Patterns. 2007 Dec;8(1):1-11
3J:214455 Willemetz A, Lenoir A, Deschemin JC, Lopez-Otin C, Ramsay AJ, Vaulont S, Nicolas G, Matriptase-2 is essential for hepcidin repression during fetal life and postnatal development in mice to maintain iron homeostasis. Blood. 2014 Jul 17;124(3):441-4
1J:168909 Xia Y, Cortez-Retamozo V, Niederkofler V, Salie R, Chen S, Samad TA, Hong CC, Arber S, Vyas JM, Weissleder R, Pittet MJ, Lin HY, Dragon (repulsive guidance molecule B) inhibits IL-6 expression in macrophages. J Immunol. 2011 Feb 1;186(3):1369-76
1*J:116886 Yoon D, Pastore YD, Divoky V, Liu E, Mlodnicka AE, Rainey K, Ponka P, Semenza GL, Schumacher A, Prchal JT, Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development. J Biol Chem. 2006 Sep 1;281(35):25703-11

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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory