About   Help   FAQ
Gene Expression Literature Summary
Symbol
Name
ID
Rgmb
repulsive guidance molecule family member B
MGI:1916049

19 matching records from 19 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E2.5 E7 E8.5 E9.5 E10.5 E11 E11.5 E12.5 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E P
Immunohistochemistry (section) 1 1 2 1 1
In situ RNA (section) 1 1 3 2 1 2 7 1 1 3 2 1 1 7
Immunohistochemistry (whole mount) 1 1
In situ RNA (whole mount) 1 1 1
In situ reporter (knock in) 1
Northern blot 1 1 1 1 2
Western blot 1
RT-PCR 1 1 2 1 1 1 1 4
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Rgmb  repulsive guidance molecule family member B   (Synonyms: 1110059F19Rik, DRAGON, RGM domain family, member B)
Results  Reference
1*J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
3J:158468 Conrad S, Stimpfle F, Montazeri S, Oldekamp J, Seid K, Alvarez-Bolado G, Skutella T, RGMb controls aggregation and migration of Neogenin-positive cells in vitro and in vivo. Mol Cell Neurosci. 2010 Feb;43(2):222-31
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
5J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46
6J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45
2J:317246 Liu J, Wang W, Liu M, Su L, Zhou H, Xia Y, Ran J, Lin HY, Yang B, Repulsive guidance molecule b inhibits renal cyst development through the bone morphogenetic protein signaling pathway. Cell Signal. 2016 Dec;28(12):1842-1851
5*J:127437 Metzger M, Conrad S, Alvarez-Bolado G, Skutella T, Just L, Gene expression of the repulsive guidance molecules during development of the mouse intestine. Dev Dyn. 2005 Sep;234(1):169-75
7J:87768 Niederkofler V, Salie R, Sigrist M, Arber S, Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci. 2004 Jan 28;24(4):808-18
2*J:89169 Oldekamp J, Kramer N, Alvarez-Bolado G, Skutella T, Expression pattern of the repulsive guidance molecules RGM A, B and C during mouse development. Gene Expr Patterns. 2004 May;4(3):283-8
1J:250766 Poliak S, Morales D, Croteau LP, Krawchuk D, Palmesino E, Morton S, Cloutier JF, Charron F, Dalva MB, Ackerman SL, Kao TJ, Kania A, Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons. Elife. 2015 Dec 3;4:e10841
3J:305520 Robinson RA, Griffiths SC, van de Haar LL, Malinauskas T, van Battum EY, Zelina P, Schwab RA, Karia D, Malinauskaite L, Brignani S, van den Munkhof MH, Dudukcu O, De Ruiter AA, Van den Heuvel DMA, Bishop B, Elegheert J, Aricescu AR, Pasterkamp RJ, Siebold C, Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell. 2021 Apr 15;184(8):2103-2120.e31
6J:98740 Samad TA, Rebbapragada A, Bell E, Zhang Y, Sidis Y, Jeong SJ, Campagna JA, Perusini S, Fabrizio DA, Schneyer AL, Lin HY, Brivanlou AH, Attisano L, Woolf CJ, DRAGON, a bone morphogenetic protein co-receptor. J Biol Chem. 2005 Apr 8;280(14):14122-9
4J:90082 Samad TA, Srinivasan A, Karchewski LA, Jeong SJ, Campagna JA, Ji RR, Fabrizio DA, Zhang Y, Lin HY, Bell E, Woolf CJ, DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J Neurosci. 2004 Feb 25;24(8):2027-36
8*J:87381 Schmidtmer J, Engelkamp D, Isolation and expression pattern of three mouse homologues of chick Rgm. Gene Expr Patterns. 2004 Jan;4(1):105-10
3*J:127109 Schnichels S, Conrad S, Warstat K, Henke-Fahle S, Skutella T, Schraermeyer U, Julien S, Gene expression of the repulsive guidance molecules/neogenin in the developing and mature mouse visual system: C57BL/6J vs. the glaucoma model DBA/2J. Gene Expr Patterns. 2007 Dec;8(1):1-11
1J:282827 Tulloch AJ, Teo S, Carvajal BV, Tessier-Lavigne M, Jaworski A, Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3(Cre) mouse. J Comp Neurol. 2019 Dec 15;527(18):2948-2972
4*J:199400 van den Heuvel DM, Hellemons AJ, Pasterkamp RJ, Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain. PLoS One. 2013;8(2):e55828
2J:168909 Xia Y, Cortez-Retamozo V, Niederkofler V, Salie R, Chen S, Samad TA, Hong CC, Arber S, Vyas JM, Weissleder R, Pittet MJ, Lin HY, Dragon (repulsive guidance molecule B) inhibits IL-6 expression in macrophages. J Immunol. 2011 Feb 1;186(3):1369-76
1J:314661 Zhang Q, Huang R, Ye Y, Guo X, Lu J, Zhu F, Gong X, Zhang Q, Yan J, Luo L, Zhuang S, Chen Y, Zhao X, Evans SM, Jiang C, Liang X, Sun Y, Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification. Cell Death Dis. 2018 Feb 14;9(2):247

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory