About   Help   FAQ
Gene Expression Literature Summary
Symbol
Name
ID
Foxp1
forkhead box P1
MGI:1914004

204 matching records from 204 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1.5 E2 E2.5 E3 E3.5 E4.5 E8.5 E9 E9.5 E10 E10.5 E11.5 E12 E12.5 E13.5 E14 E14.5 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19.5 E20 E P
Immunohistochemistry (section) 1 6 2 17 37 2 64 33 1 22 11 1 15 1 6 2 23 1 1 8 46
In situ RNA (section) 3 1 4 7 11 9 7 11 6 1 4 8 11
In situ RNA (whole mount) 1 2 2 3 3 2
In situ reporter (knock in) 1 1
Northern blot 2
Western blot 1 2 2 2 6
RT-PCR 1 1 1 1 1 1 1 1 1 2 1 5 2 5 2 2 2 4 8
cDNA clones 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Foxp1  forkhead box P1   (Synonyms: 3110052D19Rik, 4932443N09Rik)
Results  Reference
1J:222718 Adams KL, Rousso DL, Umbach JA, Novitch BG, Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells. Nat Commun. 2015;6:6778
2*J:228503 Altieri SC, Jalabi W, Zhao T, Romito-DiGiacomo RR, Maricich SM, En1 directs superior olivary complex neuron positioning, survival, and expression of FoxP1. Dev Biol. 2015 Dec 1;408(1):99-108
2J:316641 Altieri SC, Zhao T, Jalabi W, Romito-DiGiacomo RR, Maricich SM, En1 is necessary for survival of neurons in the ventral nuclei of the lateral lemniscus. Dev Neurobiol. 2016 Nov;76(11):1266-1274
1J:282739 Alvarez-Saavedra M, Yan K, De Repentigny Y, Hashem LE, Chaudary N, Sarwar S, Yang D, Ioshikhes I, Kothary R, Hirayama T, Yagi T, Picketts DJ, Snf2h Drives Chromatin Remodeling to Prime Upper Layer Cortical Neuron Development. Front Mol Neurosci. 2019;12:243
3J:226616 Araujo DJ, Anderson AG, Berto S, Runnels W, Harper M, Ammanuel S, Rieger MA, Huang HC, Rajkovich K, Loerwald KW, Dekker JD, Tucker HO, Dougherty JD, Gibson JR, Konopka G, FoxP1 orchestration of ASD-relevant signaling pathways in the striatum. Genes Dev. 2015 Oct 15;29(20):2081-96
2J:131380 Arlotta P, Molyneaux BJ, Jabaudon D, Yoshida Y, Macklis JD, Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. J Neurosci. 2008 Jan 16;28(3):622-32
1J:173570 Asprer JS, Lee B, Wu CS, Vadakkan T, Dickinson ME, Lu HC, Lee SK, LMO4 functions as a co-activator of neurogenin 2 in the developing cortex. Development. 2011 Jul;138(13):2823-32
2J:112701 Bailey PJ, Klos JM, Andersson E, Karlen M, Kallstrom M, Ponjavic J, Muhr J, Lenhard B, Sandelin A, Ericson J, A global genomic transcriptional code associated with CNS-expressed genes. Exp Cell Res. 2006 Oct 1;312(16):3108-19
2J:213829 Bard-Chapeau EA, Szumska D, Jacob B, Chua BQ, Chatterjee GC, Zhang Y, Ward JM, Urun F, Kinameri E, Vincent SD, Ahmed S, Bhattacharya S, Osato M, Perkins AS, Moore AW, Jenkins NA, Copeland NG, Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects. PLoS One. 2014;9(2):e89397
1J:276248 Bonanomi D, Valenza F, Chivatakarn O, Sternfeld MJ, Driscoll SP, Aslanian A, Lettieri K, Gullo M, Badaloni A, Lewcock JW, Hunter T, Pfaff SL, p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts. Neuron. 2019 May 8;102(3):602-620.e9
1J:315765 Borrell V, Cardenas A, Ciceri G, Galceran J, Flames N, Pla R, Nobrega-Pereira S, Garcia-Frigola C, Peregrin S, Zhao Z, Ma L, Tessier-Lavigne M, Marin O, Slit/Robo signaling modulates the proliferation of central nervous system progenitors. Neuron. 2012 Oct 18;76(2):338-52
1J:239777 Boucherat O, Landry-Truchon K, Berube-Simard FA, Houde N, Beuret L, Lezmi G, Foulkes WD, Delacourt C, Charron J, Jeannotte L, Epithelial inactivation of Yy1 abrogates lung branching morphogenesis. Development. 2015 Sep 01;142(17):2981-95
2*J:313372 Braccioli L, Vervoort SJ, Adolfs Y, Heijnen CJ, Basak O, Pasterkamp RJ, Nijboer CH, Coffer PJ, FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression. Stem Cell Reports. 2017 Nov 14;9(5):1530-1545
5J:322321 Catela C, Chen Y, Weng Y, Wen K, Kratsios P, Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. Elife. 2022 Mar 22;11:e70766
1J:272505 Catela C, Correa E, Wen K, Aburas J, Croci L, Consalez GG, Kratsios P, An ancient role for collier/Olf/Ebf (COE)-type transcription factors in axial motor neuron development. Neural Dev. 2019 Jan 18;14(1):2
2J:277959 Catela C, Shin MM, Lee DH, Liu JP, Dasen JS, Hox Proteins Coordinate Motor Neuron Differentiation and Connectivity Programs through Ret/Gfralpha Genes. Cell Rep. 2016 Mar 1;14(8):1901-15
8*J:231581 Cesario JM, Almaidhan AA, Jeong J, Expression of forkhead box transcription factor genes Foxp1 and Foxp2 during jaw development. Gene Expr Patterns. 2016 Mar;20(2):111-9
1J:225434 Cesario JM, Landin Malt A, Deacon LJ, Sandberg M, Vogt D, Tang Z, Zhao Y, Brown S, Rubenstein JL, Jeong J, Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57Kip2. Hum Mol Genet. 2015 Sep 1;24(17):5024-39
1J:215832 Chai G, Zhou L, Manto M, Helmbacher F, Clotman F, Goffinet AM, Tissir F, Celsr3 is required in motor neurons to steer their axons in the hindlimb. Nat Neurosci. 2014 Sep;17(9):1171-9
2J:284139 Chaimowicz C, Ruffault PL, Cheret C, Woehler A, Zampieri N, Fortin G, Garratt AN, Birchmeier C, Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse. Development. 2019 Sep 6;146(17):dev174045
1J:257637 Chang CJ, Chang MY, Chou SY, Huang CC, Chuang JY, Hsu TI, Chang HF, Wu YH, Wu CC, Morales D, Kania A, Kao TJ, Ephexin1 Is Required for Eph-Mediated Limb Trajectory of Spinal Motor Axons. J Neurosci. 2018 Feb 21;38(8):2043-2056
1J:304721 Chang SH, Su YC, Chang M, Chen JA, MicroRNAs mediate precise control of spinal interneuron populations to exert delicate sensory-to-motor outputs. Elife. 2021 Mar 31;10:e63768
1J:173924 Chatzi C, Brade T, Duester G, Retinoic acid functions as a key GABAergic differentiation signal in the basal ganglia. PLoS Biol. 2011 Apr;9(4):e1000609
1J:174745 Chen JA, Huang YP, Mazzoni EO, Tan GC, Zavadil J, Wichterle H, Mir-17-3p controls spinal neural progenitor patterning by regulating Olig2/Irx3 cross-repressive loop. Neuron. 2011 Feb 24;69(4):721-35
2J:190166 Chen JA, Wichterle H, Apoptosis of limb innervating motor neurons and erosion of motor pool identity upon lineage specific dicer inactivation. Front Neurosci. 2012;6:69
1*J:143541 Chen L, Melendez J, Campbell K, Kuan CY, Zheng Y, Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly. Dev Biol. 2009 Jan 1;325(1):162-70
1J:339854 Chen SY, Liu FC, The Fgf9-Nolz1-Wnt2 axis regulates morphogenesis of the lung. Development. 2023 Aug 15;150(16):dev201827
2J:286635 Chen SY, Lu KM, Ko HA, Huang TH, Hao JH, Yan YT, Chang SL, Evans SM, Liu FC, Parcellation of the striatal complex into dorsal and ventral districts. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7418-7429
1J:238975 Clovis YM, Seo SY, Kwon JS, Rhee JC, Yeo S, Lee JW, Lee S, Lee SK, Chx10 Consolidates V2a Interneuron Identity through Two Distinct Gene Repression Modes. Cell Rep. 2016 Aug 09;16(6):1642-52
6*J:98919 Cobb J, Duboule D, Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia. Development. 2005 Jul;132(13):3055-67
1J:158610 Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, Toth JI, Fong LG, Young SG, Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5076-81
1J:156578 Cubelos B, Sebastian-Serrano A, Kim S, Moreno-Ortiz C, Redondo JM, Walsh CA, Nieto M, Cux-2 controls the proliferation of neuronal intermediate precursors of the cortical subventricular zone. Cereb Cortex. 2008 Aug;18(8):1758-70
10J:139297 Dasen JS, De Camilli A, Wang B, Tucker PW, Jessell TM, Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1. Cell. 2008 Jul 25;134(2):304-16
1J:299679 Debrulle S, Baudouin C, Hidalgo-Figueroa M, Pelosi B, Francius C, Rucchin V, Ronellenfitch K, Chow RL, Tissir F, Lee SK, Clotman F, Vsx1 and Chx10 paralogs sequentially secure V2 interneuron identity during spinal cord development. Cell Mol Life Sci. 2020 Oct;77(20):4117-4131
1J:278241 Delile J, Rayon T, Melchionda M, Edwards A, Briscoe J, Sagner A, Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord. Development. 2019 Mar 27;146(12):dev173807
2J:178688 Demireva EY, Shapiro LS, Jessell TM, Zampieri N, Motor neuron position and topographic order imposed by beta- and gamma-catenin activities. Cell. 2011 Oct 28;147(3):641-52
1J:344351 Deska-Gauthier D, Borowska-Fielding J, Jones C, Zhang H, MacKay CS, Michail R, Bennett LA, Bikoff JB, Zhang Y, Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity. Cell Rep. 2023 Dec 29;43(1):113635
1J:105301 Deuel TA, Liu JS, Corbo JC, Yoo SY, Rorke-Adams LB, Walsh CA, Genetic interactions between doublecortin and doublecortin-like kinase in neuronal migration and axon outgrowth. Neuron. 2006 Jan 5;49(1):41-53
2J:271772 Dewitz C, Pimpinella S, Hackel P, Akalin A, Jessell TM, Zampieri N, Nuclear Organization in the Spinal Cord Depends on Motor Neuron Lamination Orchestrated by Catenin and Afadin Function. Cell Rep. 2018 Feb 13;22(7):1681-1694
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:328712 Du H, Wang Z, Guo R, Yang L, Liu G, Zhang Z, Xu Z, Tian Y, Yang Z, Li X, Chen B, Transcription factors Bcl11a and Bcl11b are required for the production and differentiation of cortical projection neurons. Cereb Cortex. 2022 Aug 22;32(17):3611-3632
1J:262482 Dubos A, Meziane H, Iacono G, Curie A, Riet F, Martin C, Loaec N, Birling MC, Selloum M, Normand E, Pavlovic G, Sorg T, Stunnenberg HG, Chelly J, Humeau Y, Friocourt G, Herault Y, A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations. Hum Mol Genet. 2018 Jun 15;27(12):2138-2153
4J:262472 Edmond M, Hanley O, Philippidou P, Topoisomerase IIbeta Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs. eNeuro. 2017 Nov-Dec;4(6):ENEURO.0404-17.2017
1J:201994 Ehrman LA, Mu X, Waclaw RR, Yoshida Y, Vorhees CV, Klein WH, Campbell K, The LIM homeobox gene Isl1 is required for the correct development of the striatonigral pathway in the mouse. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):E4026-35
2J:237201 Espinosa-Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson WD, Brunet JF, The sacral autonomic outflow is sympathetic. Science. 2016 Nov 18;354(6314):893-897
8*J:83154 Ferland RJ, Cherry TJ, Preware PO, Morrisey EE, Walsh CA, Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain. J Comp Neurol. 2003 May 26;460(2):266-79
3J:158231 Francius C, Clotman F, Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development. Neuroscience. 2010 Jan 13;165(1):116-29
1*J:125023 French CA, Groszer M, Preece C, Coupe AM, Rajewsky K, Fisher SE, Generation of mice with a conditional Foxp2 null allele. Genesis. 2007 Jul;45(7):440-6
1J:282364 Frendo ME, da Silva A, Phan KD, Riche S, Butler SJ, The Cofilin/Limk1 Pathway Controls the Growth Rate of Both Developing and Regenerating Motor Axons. J Neurosci. 2019 Nov 20;39(47):9316-9327
6*J:242047 Frohlich H, Rafiullah R, Schmitt N, Abele S, Rappold GA, Foxp1 expression is essential for sex-specific murine neonatal ultrasonic vocalization. Hum Mol Genet. 2017 Apr 15;26(8):1511-1521
1*J:138839 Fulp CT, Cho G, Marsh ED, Nasrallah IM, Labosky PA, Golden JA, Identification of Arx transcriptional targets in the developing basal forebrain. Hum Mol Genet. 2008;17(23):3740-60
1J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36
2J:279182 Genabai NK, Kannan A, Ahmad S, Jiang X, Bhatia K, Gangwani L, Deregulation of ZPR1 causes respiratory failure in spinal muscular atrophy. Sci Rep. 2017 Aug 15;7(1):8295
2J:321672 Goodwin K, Jaslove JM, Tao H, Zhu M, Hopyan S, Nelson CM, Patterning the embryonic pulmonary mesenchyme. iScience. 2022 Mar 18;25(3):103838
1J:332216 Govek KW, Chen S, Sgourdou P, Yao Y, Woodhouse S, Chen T, Fuccillo MV, Epstein DJ, Camara PG, Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation. Cell Rep. 2022 Dec 6;41(10):111768
1J:305179 Gray de Cristoforis A, Ferrari F, Clotman F, Vogel T, Differentiation and localization of interneurons in the developing spinal cord depends on DOT1L expression. Mol Brain. 2020 May 29;13(1):85
2*J:229257 Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y, Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
7*J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
4J:292325 Hagey DW, Topcic D, Kee N, Reynaud F, Bergsland M, Perlmann T, Muhr J, CYCLIN-B1/2 and -D1 act in opposition to coordinate cortical progenitor self-renewal and lineage commitment. Nat Commun. 2020 Jun 9;11(1):2898
1J:87404 Hanashima C, Li SC, Shen L, Lai E, Fishell G, Foxg1 suppresses early cortical cell fate. Science. 2004 Jan 2;303(5654):56-9
2J:253351 Hanley O, Zewdu R, Cohen LJ, Jung H, Lacombe J, Philippidou P, Lee DH, Selleri L, Dasen JS, Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns. Neuron. 2016 Sep 7;91(5):1005-1020
1J:245009 Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti HH, Ermakova O, Rempel E, Stoeckli ET, Ruiz de Almodovar C, Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun. 2017 Mar 06;8:14583
1J:238096 Houlihan SL, Lanctot AA, Guo Y, Feng Y, Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis. Elife. 2016 Sep 24;5:e17823
2J:345795 Hsu HC, Hsu SP, Hsu FY, Chang M, Chen JA, LncRNA Litchi is a regulator for harmonizing maturity and resilient functionality in spinal motor neurons. iScience. 2024 Mar 15;27(3):109207
2J:226479 Hua ZL, Emiliani FE, Nathans J, Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems. Neural Dev. 2015;10(1):21
2J:207894 Hua ZL, Smallwood PM, Nathans J, Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons. Elife. 2013;2:e01482
3J:231979 Huettl RE, Eckstein S, Stahl T, Petricca S, Ninkovic J, Gotz M, Huber AB, Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development. Dev Biol. 2016 May 1;413(1):86-103
1J:170679 Huettl RE, Soellner H, Bianchi E, Novitch BG, Huber AB, Npn-1 contributes to axon-axon interactions that differentially control sensory and motor innervation of the limb. PLoS Biol. 2011 Feb;9(2):e1001020
1J:316683 Huh MS, Ivanochko D, Hashem LE, Curtin M, Delorme M, Goodall E, Yan K, Picketts DJ, Stalled replication forks within heterochromatin require ATRX for protection. Cell Death Dis. 2016 May 12;7:e2220
1J:279053 Ito H, Shiwaku H, Yoshida C, Homma H, Luo H, Chen X, Fujita K, Musante L, Fischer U, Frints SG, Romano C, Ikeuchi Y, Shimamura T, Imoto S, Miyano S, Muramatsu SI, Kawauchi T, Hoshino M, Sudol M, Arumughan A, Wanker EE, Rich T, Schwartz C, Matsuzaki F, Bonni A, Kalscheuer VM, Okazawa H, In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells. Mol Psychiatry. 2015 Apr;20(4):459-71
1J:196454 Julian LM, Vandenbosch R, Pakenham CA, Andrusiak MG, Nguyen AP, McClellan KA, Svoboda DS, Lagace DC, Park DS, Leone G, Blais A, Slack RS, Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells. Cell Stem Cell. 2013 Apr 4;12(4):440-52
4J:166088 Jung H, Lacombe J, Mazzoni EO, Liem KF Jr, Grinstein J, Mahony S, Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H, Dasen JS, Global control of motor neuron topography mediated by the repressive actions of a single hox gene. Neuron. 2010 Sep 9;67(5):781-96
1J:219882 Kao TJ, Nicholl GC, Johansen JA, Kania A, Beg AA, alpha2-chimaerin is required for Eph receptor-class-specific spinal motor axon guidance and coordinate activation of antagonistic muscles. J Neurosci. 2015 Feb 11;35(6):2344-57
2J:148253 Kao TJ, Palmesino E, Kania A, SRC family kinases are required for limb trajectory selection by spinal motor axons. J Neurosci. 2009 Apr 29;29(17):5690-700
1J:324271 Kao TJ, Wang CY, Hsu TI, Wu YH, Chuang JY, Huang CC, Hsieh CT, TDP-43 is essential for Eph receptor-class-specific spinal motor axon trajectory into the limb. Neurosci Res. 2022 Mar;176:31-39
1J:186538 Katayama K, Leslie JR, Lang RA, Zheng Y, Yoshida Y, Left-Right Locomotor Circuitry Depends on RhoA-Driven Organization of the Neuroepithelium in the Developing Spinal Cord. J Neurosci. 2012 Jul 25;32(30):10396-407
1J:198828 Kelly CE, Thymiakou E, Dixon JE, Tanaka S, Godwin J, Episkopou V, Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension. PLoS Biol. 2013;11(4):e1001538
1J:326949 Kirjavainen A, Singh P, Lahti L, Seja P, Lelkes Z, Makkonen A, Kilpinen S, Ono Y, Salminen M, Aitta-Aho T, Stenberg T, Molchanova S, Achim K, Partanen J, Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons. Development. 2022 Jul 15;149(14):dev200937
1J:152416 Kitamura K, Itou Y, Yanazawa M, Ohsawa M, Suzuki-Migishima R, Umeki Y, Hohjoh H, Yanagawa Y, Shinba T, Itoh M, Nakamura K, Goto Y, Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice. Hum Mol Genet. 2009 Oct 1;18(19):3708-24
1J:201551 Ko HA, Chen SY, Chen HY, Hao HJ, Liu FC, Cell type-selective expression of the zinc finger-containing gene Nolz-1/Zfp503 in the developing mouse striatum. Neurosci Lett. 2013 Aug 26;548:44-9
2J:221657 Kong JH, Yang L, Dessaud E, Chuang K, Moore DM, Rohatgi R, Briscoe J, Novitch BG, Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling. Dev Cell. 2015 May 26;33(4):373-87
1*J:160253 Konstantoulas CJ, Parmar M, Li M, FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3. J Neurochem. 2010 May;113(4):836-47
2*J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1J:225880 Kraushar ML, Viljetic B, Wijeratne HR, Thompson K, Jiao X, Pike JW, Medvedeva V, Groszer M, Kiledjian M, Hart RP, Rasin MR, Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes. J Neurosci. 2015 Aug 5;35(31):10911-26
1J:256526 Kuerbitz J, Arnett M, Ehrman S, Williams MT, Vorhees CV, Fisher SE, Garratt AN, Muglia LJ, Waclaw RR, Campbell K, Loss of Intercalated Cells (ITCs) in the Mouse Amygdala of Tshz1 Mutants Correlates with Fear, Depression, and Social Interaction Phenotypes. J Neurosci. 2018 Jan 31;38(5):1160-1177
1J:303293 Kuerbitz J, Madhavan M, Ehrman LA, Kohli V, Waclaw RR, Campbell K, Temporally Distinct Roles for the Zinc Finger Transcription Factor Sp8 in the Generation and Migration of Dorsal Lateral Ganglionic Eminence (dLGE)-Derived Neuronal Subtypes in the Mouse. Cereb Cortex. 2021 Feb 5;31(3):1744-1762
5J:195163 Lacombe J, Hanley O, Jung H, Philippidou P, Surmeli G, Grinstein J, Dasen JS, Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons. PLoS Genet. 2013 Jan;9(1):e1003184
3J:239986 Lahti L, Haugas M, Tikker L, Airavaara M, Voutilainen MH, Anttila J, Kumar S, Inkinen C, Salminen M, Partanen J, Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei. Development. 2016 Feb 01;143(3):516-29
1J:182759 Lahti L, Peltopuro P, Piepponen TP, Partanen J, Cell-autonomous FGF signaling regulates anteroposterior patterning and neuronal differentiation in the mesodiencephalic dopaminergic progenitor domain. Development. 2012 Mar;139(5):894-905
1J:254235 Lanctot AA, Guo Y, Le Y, Edens BM, Nowakowski RS, Feng Y, Loss of Brap Results in Premature G1/S Phase Transition and Impeded Neural Progenitor Differentiation. Cell Rep. 2017 Aug 1;20(5):1148-1160
1J:99181 Laub F, Lei L, Sumiyoshi H, Kajimura D, Dragomir C, Smaldone S, Puche AC, Petros TJ, Mason C, Parada LF, Ramirez F, Transcription Factor KLF7 Is Important for Neuronal Morphogenesis in Selected Regions of the Nervous System. Mol Cell Biol. 2005 Jul;25(13):5699-711
3J:237131 Lauriol J, Cabrera JR, Roy A, Keith K, Hough SM, Damilano F, Wang B, Segarra GC, Flessa ME, Miller LE, Das S, Bronson R, Lee KH, Kontaridis MI, Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines. J Clin Invest. 2016 Aug 01;126(8):2989-3005
1J:243634 Laussu J, Audouard C, Kischel A, Assis-Nascimento P, Escalas N, Liebl DJ, Soula C, Davy A, Eph/Ephrin Signaling Controls Progenitor Identities In The Ventral Spinal Cord. Neural Dev. 2017 Jun 08;12(1):10
1J:255020 Lee H, Kim M, Kim N, Macfarlan T, Pfaff SL, Mastick GS, Song MR, Slit and Semaphorin signaling governed by Islet transcription factors positions motor neuron somata within the neural tube. Exp Neurol. 2015 Jul;269:17-27
1J:203926 Lee H, Song MR, The structural role of radial glial endfeet in confining spinal motor neuron somata is controlled by the Reelin and Notch pathways. Exp Neurol. 2013 Nov;249:83-94
1J:191367 Lee Y, Katyal S, Downing SM, Zhao J, Russell HR, McKinnon PJ, Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors. Nat Neurosci. 2012 Jun;15(6):819-26
1J:181920 Lee Y, Shull ER, Frappart PO, Katyal S, Enriquez-Rios V, Zhao J, Russell HR, Brown EJ, McKinnon PJ, ATR maintains select progenitors during nervous system development. EMBO J. 2012 Mar 7;31(5):1177-89
2J:185603 Li S, Wang Y, Zhang Y, Lu MM, Demayo FJ, Dekker JD, Tucker PW, Morrisey EE, Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2. Development. 2012 Jul;139(14):2500-9
1J:213871 Li X, Liu Z, Qiu M, Yang Z, Sp8 plays a supplementary role to Pax6 in establishing the pMN/p3 domain boundary in the spinal cord. Development. 2014 Jul;141(14):2875-84
2*J:237748 Li X, Xiao J, Frohlich H, Tu X, Li L, Xu Y, Cao H, Qu J, Rappold GA, Chen JG, Foxp1 regulates cortical radial migration and neuronal morphogenesis in developing cerebral cortex. PLoS One. 2015;10(5):e0127671
1J:332369 Liau ES, Jin S, Chen YC, Liu WS, Calon M, Nedelec S, Nie Q, Chen JA, Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons. Nat Commun. 2023 Jan 3;14(1):46
1J:220445 Liu Z, Brunskill E, Boyle S, Chen S, Turkoz M, Guo Y, Grant R, Kopan R, Second-generation Notch1 activity-trap mouse line (N1IP::CreHI) provides a more comprehensive map of cells experiencing Notch1 activity. Development. 2015 Mar 15;142(6):1193-202
1*J:173286 Long JE, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
1*J:173287 Long JE, Swan C, Liang WS, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
1J:308430 Lopez-Gonzalez L, Alonso A, Garcia-Calero E, de Puelles E, Puelles L, Tangential Intrahypothalamic Migration of the Mouse Ventral Premamillary Nucleus and Fgf8 Signaling. Front Cell Dev Biol. 2021;9:676121
3*J:82200 Lu MM, Li S, Yang H, Morrisey EE, Foxp4: a novel member of the Foxp subfamily of winged-helix genes co-expressed with Foxp1 and Foxp2 in pulmonary and gut tissues. Mech Dev. 2002 Dec;119 Suppl 1:S197-202
1J:176643 Luria V, Krawchuk D, Jessell TM, Laufer E, Kania A, Specification of motor axon trajectory by ephrin-B:EphB signaling: symmetrical control of axonal patterning in the developing limb. Neuron. 2008 Dec 26;60(6):1039-53
1J:165487 Magnani D, Hasenpusch-Theil K, Jacobs EC, Campagnoni AT, Price DJ, Theil T, The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence. J Neurosci. 2010 Oct 13;30(41):13883-94
1J:221648 Mao H, Pilaz LJ, McMahon JJ, Golzio C, Wu D, Shi L, Katsanis N, Silver DL, Rbm8a haploinsufficiency disrupts embryonic cortical development resulting in microcephaly. J Neurosci. 2015 May 6;35(18):7003-18
1J:338454 Marfull-Oromi P, Fleitas C, Zammou B, Rocandio D, Ballester-Lurbe B, Terrado J, Perez-Roger I, Espinet C, Egea J, Genetic ablation of the Rho GTPase Rnd3 triggers developmental defects in internal capsule and the globus pallidus formation. J Neurochem. 2021 Jul;158(2):197-216
1J:316266 Martin-Ibanez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, Martinez S, Campbell K, Vicario-Abejon C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM, Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons. Stem Cells Dev. 2012 Aug 10;21(12):2239-51
1J:261809 Mayer C, Hafemeister C, Bandler RC, Machold R, Batista Brito R, Jaglin X, Allaway K, Butler A, Fishell G, Satija R, Developmental diversification of cortical inhibitory interneurons. Nature. 2018 Mar 22;555(7697):457-462
2J:256105 Mendelsohn AI, Dasen JS, Jessell TM, Divergent Hox Coding and Evasion of Retinoid Signaling Specifies Motor Neurons Innervating Digit Muscles. Neuron. 2017 Feb 22;93(4):792-805.e4
1J:239291 Metzakopian E, Bouhali K, Alvarez-Saavedra M, Whitsett JA, Picketts DJ, Ang SL, Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells. Development. 2015 Apr 01;142(7):1315-24
1J:185583 Metzakopian E, Lin W, Salmon-Divon M, Dvinge H, Andersson E, Ericson J, Perlmann T, Whitsett JA, Bertone P, Ang SL, Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors. Development. 2012 Jul;139(14):2625-34
1J:210605 Molofsky AV, Kelley KW, Tsai HH, Redmond SA, Chang SM, Madireddy L, Chan JR, Baranzini SE, Ullian EM, Rowitch DH, Astrocyte-encoded positional cues maintain sensorimotor circuit integrity. Nature. 2014 May 8;509(7499):189-94
1J:232899 Moon UY, Park JY, Park R, Cho JY, Hughes LJ, McKenna J 3rd, Goetzl L, Cho SH, Crino PB, Gambello MJ, Kim S, Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex. Cell Rep. 2015 Aug 11;12(6):965-78
5J:305279 Morello F, Borshagovski D, Survila M, Tikker L, Sadik-Ogli S, Kirjavainen A, Estartus N, Knaapi L, Lahti L, Toronen P, Mazutis L, Delogu A, Salminen M, Achim K, Partanen J, Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain. Cell Rep. 2020 Oct 13;33(2):108268
2J:226687 Morello F, Prasad AA, Rehberg K, Vieira de Sa R, Anton-Bolanos N, Leyva-Diaz E, Adolfs Y, Tissir F, Lopez-Bendito G, Pasterkamp RJ, Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development. J Neurosci. 2015 Oct 21;35(42):14205-19
17J:156251 Morikawa Y, Komori T, Hisaoka T, Senba E, Detailed expression pattern of Foxp1 and its possible roles in neurons of the spinal cord during embryogenesis. Dev Neurosci. 2009;31(6):511-22
2J:277700 Nam H, Jeon S, An H, Yoo J, Lee HJ, Lee SK, Lee S, Critical roles of ARHGAP36 as a signal transduction mediator of Shh pathway in lateral motor columnar specification. Elife. 2019 Jul 15;8:e46683
1J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54
1J:281436 Nicol B, Grimm SA, Chalmel F, Lecluze E, Pannetier M, Pailhoux E, Dupin-De-Beyssat E, Guiguen Y, Capel B, Yao HH, RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2. Nat Commun. 2019 Nov 11;10(1):5116
1J:197985 Ota H, Sakurai M, Gupta R, Valente L, Wulff BE, Ariyoshi K, Iizasa H, Davuluri RV, Nishikura K, ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing. Cell. 2013 Apr 25;153(3):575-89
4J:166792 Palmesino E, Rousso DL, Kao TJ, Klar A, Laufer E, Uemura O, Okamoto H, Novitch BG, Kania A, Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling. PLoS Biol. 2010;8(8):e1000446
2*J:314938 Park Y, Lofton M, Li D, Rasin MR, Extrinsic Regulators of mRNA Translation in Developing Brain: Story of WNTs. Cells. 2021 Jan 28;10(2)
2J:265044 Parras A, Anta H, Santos-Galindo M, Swarup V, Elorza A, Nieto-Gonzalez JL, Pico S, Hernandez IH, Diaz-Hernandez JI, Belloc E, Rodolosse A, Parikshak NN, Penagarikano O, Fernandez-Chacon R, Irimia M, Navarro P, Geschwind DH, Mendez R, Lucas JJ, Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing. Nature. 2018 Aug;560(7719):441-446
1J:138579 Pawlisz AS, Mutch C, Wynshaw-Boris A, Chenn A, Walsh CA, Feng Y, Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination. Hum Mol Genet. 2008 Aug 15;17(16):2441-55
19J:287008 Pearson CA, Moore DM, Tucker HO, Dekker JD, Hu H, Miquelajauregui A, Novitch BG, Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. Cell Rep. 2020 Feb 11;30(6):1964-1981.e3
3J:197494 Philippidou P, Walsh CM, Aubin J, Jeannotte L, Dasen JS, Sustained Hox5 gene activity is required for respiratory motor neuron development. Nat Neurosci. 2012 Dec;15(12):1636-44
1J:198549 Pietri S, Dimidschstein J, Tiberi L, Sotiropoulou PA, Bilheu A, Goffinet A, Achouri Y, Tissir F, Blanpain C, Jacquemin P, Vanderhaeghen P, Transcriptional mechanisms of EphA7 gene expression in the developing cerebral cortex. Cereb Cortex. 2012 Jul;22(7):1678-89
2*J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617
2J:250766 Poliak S, Morales D, Croteau LP, Krawchuk D, Palmesino E, Morton S, Cloutier JF, Charron F, Dalva MB, Ackerman SL, Kao TJ, Kania A, Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons. Elife. 2015 Dec 3;4:e10841
1J:178712 Postiglione MP, Juschke C, Xie Y, Haas GA, Charalambous C, Knoblich JA, Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex. Neuron. 2011 Oct 20;72(2):269-84
1J:157825 Pramparo T, Youn YH, Yingling J, Hirotsune S, Wynshaw-Boris A, Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction. J Neurosci. 2010 Feb 24;30(8):3002-12
8J:236735 Precious SV, Kelly CM, Reddington AE, Vinh NN, Stickland RC, Pekarik V, Scherf C, Jeyasingham R, Glasbey J, Holeiter M, Jones L, Taylor MV, Rosser AE, FoxP1 marks medium spiny neurons from precursors to maturity and is required for their differentiation. Exp Neurol. 2016 Aug;282:9-18
1J:344102 Racedo SE, Liu Y, Shi L, Zheng D, Morrow BE, Dgcr8 functions in the secondary heart field for outflow tract and right ventricle development in mammals. Dev Biol. 2024 Feb;506:72-84
1J:146180 Regad T, Bellodi C, Nicotera P, Salomoni P, The tumor suppressor Pml regulates cell fate in the developing neocortex. Nat Neurosci. 2009 Feb;12(2):132-40
4J:188384 Rousso DL, Pearson CA, Gaber ZB, Miquelajauregui A, Li S, Portera-Cailliau C, Morrisey EE, Novitch BG, Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS. Neuron. 2012 Apr 26;74(2):314-30
1J:235958 Rousso DL, Qiao M, Kagan RD, Yamagata M, Palmiter RD, Sanes JR, Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression. Cell Rep. 2016 May 31;15(9):1930-44
3J:274433 Roy A, Francius C, Rousso DL, Seuntjens E, Debruyn J, Luxenhofer G, Huber AB, Huylebroeck D, Novitch BG, Clotman F, Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification. Development. 2012 Sep;139(17):3109-19
3J:178550 Sabharwal P, Lee C, Park S, Rao M, Sockanathan S, GDE2 regulates subtype-specific motor neuron generation through inhibition of Notch signaling. Neuron. 2011 Sep 22;71(6):1058-70
5J:246732 Saller MM, Huettl RE, Hanuschick P, Amend AL, Alberton P, Aszodi A, Huber AB, The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development. J Cell Sci. 2016 Sep 01;129(17):3295-308
1J:317827 Sawai A, Pfennig S, Bulajic M, Miller A, Khodadadi-Jamayran A, Mazzoni EO, Dasen JS, PRC1 sustains the integrity of neural fate in the absence of PRC2 function. Elife. 2022 Jan 7;11:e72769
2J:168563 Shi Y, Liu JP, Gdf11 facilitates temporal progression of neurogenesis in the developing spinal cord. J Neurosci. 2011 Jan 19;31(3):883-93
1J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
1J:276848 Shimada IS, Somatilaka BN, Hwang SH, Anderson AG, Shelton JM, Rajaram V, Konopka G, Mukhopadhyay S, Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities. Dev Biol. 2019 Jun 1;450(1):47-62
3J:121421 Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE, Foxp2 and Foxp1 cooperatively regulate lung and esophagus development. Development. 2007 May;134(10):1991-2000
4*J:70542 Shu W, Yang H, Zhang L, Lu MM, Morrisey EE, Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors. J Biol Chem. 2001 Jul 20;276(29):27488-97
1J:159625 Silver DL, Watkins-Chow DE, Schreck KC, Pierfelice TJ, Larson DM, Burnetti AJ, Liaw HJ, Myung K, Walsh CA, Gaiano N, Pavan WJ, The exon junction complex component Magoh controls brain size by regulating neural stem cell division. Nat Neurosci. 2010 May;13(5):551-8
1J:135239 Skidmore JM, Cramer JD, Martin JF, Martin DM, Cre fate mapping reveals lineage specific defects in neuronal migration with loss of Pitx2 function in the developing mouse hypothalamus and subthalamic nucleus. Mol Cell Neurosci. 2008 Apr;37(4):696-707
1J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17
4J:290119 Soleilhavoup C, Travaglio M, Patrick K, Garcao P, Boobalan E, Adolfs Y, Spriggs RV, Moles-Garcia E, Dhiraj D, Oosterveen T, Ferri SL, Abel T, Brodkin ES, Pasterkamp RJ, Brooks BP, Panman L, Nolz1 expression is required in dopaminergic axon guidance and striatal innervation. Nat Commun. 2020 Jun 19;11(1):3111
4J:225920 Spaeth JM, Hunter CS, Bonatakis L, Guo M, French CA, Slack I, Hara M, Fisher SE, Ferrer J, Morrisey EE, Stanger BZ, Stein R, The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice. Diabetologia. 2015 Aug;58(8):1836-44
1J:178995 Stam FJ, Hendricks TJ, Zhang J, Geiman EJ, Francius C, Labosky PA, Clotman F, Goulding M, Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program. Development. 2012 Jan;139(1):179-90
2J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035
3J:287691 Suter TACS, Blagburn SV, Fisher SE, Anderson-Keightly HM, D'Elia KP, Jaworski A, TAG-1 Multifunctionality Coordinates Neuronal Migration, Axon Guidance, and Fasciculation. Cell Rep. 2020 Jan 28;30(4):1164-1177.e7
9J:254701 Suzuki-Kerr H, Baba Y, Tsuhako A, Koso H, Dekker JD, Tucker HO, Kuribayashi H, Watanabe S, Forkhead Box Protein P1 Is Dispensable for Retina but Essential for Lens Development. Invest Ophthalmol Vis Sci. 2017 Apr 1;58(4):1916-1929
2J:203999 Svoboda DS, Paquin A, Park DS, Slack RS, Pocket proteins pRb and p107 are required for cortical lamination independent of apoptosis. Dev Biol. 2013 Dec 1;384(1):101-13
1J:308676 Talley MJ, Nardini D, Qin S, Prada CE, Ehrman LA, Waclaw RR, A role for sustained MAPK activity in the mouse ventral telencephalon. Dev Biol. 2021 Aug;476:137-147
6*J:83322 Tamura S, Morikawa Y, Iwanishi H, Hisaoka T, Senba E, Expression pattern of the winged-helix/forkhead transcription factor Foxp1 in the developing central nervous system. Gene Expr Patterns. 2003 May;3(2):193-7
4*J:89988 Tamura S, Morikawa Y, Iwanishi H, Hisaoka T, Senba E, Foxp1 gene expression in projection neurons of the mouse striatum. Neuroscience. 2004;124(2):261-7
3J:277380 Telley L, Agirman G, Prados J, Amberg N, Fievre S, Oberst P, Bartolini G, Vitali I, Cadilhac C, Hippenmeyer S, Nguyen L, Dayer A, Jabaudon D, Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex. Science. 2019 May 10;364(6440)
15J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4
2J:342618 Thomasen PB, Salasova A, Kjaer-Sorensen K, Woloszczukova L, Lavicky J, Login H, Tranberg-Jensen J, Almeida S, Beel S, Kavkova M, Qvist P, Kjolby M, Ovesen PL, Nolte S, Vestergaard B, Udrea AC, Nejsum LN, Chao MV, Van Damme P, Krivanek J, Dasen J, Oxvig C, Nykjaer A, SorCS2 binds progranulin to regulate motor neuron development. Cell Rep. 2023 Oct 26;42(11):113333
5*J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1J:297100 Tikker L, Casarotto P, Singh P, Biojone C, Piepponen TP, Estartus N, Seelbach A, Sridharan R, Laukkanen L, Castren E, Partanen J, Inactivation of the GATA Cofactor ZFPM1 Results in Abnormal Development of Dorsal Raphe Serotonergic Neuron Subtypes and Increased Anxiety-Like Behavior. J Neurosci. 2020 Nov 4;40(45):8669-8682
3J:255379 Tinterri A, Deck M, Keita M, Mailhes C, Rubin AN, Kessaris N, Lokmane L, Bielle F, Garel S, Tangential migration of corridor guidepost neurons contributes to anxiety circuits. J Comp Neurol. 2018 Feb 15;526(3):397-411
2J:293140 Toch M, Harris A, Schakman O, Kondratskaya E, Boulland JL, Dauguet N, Debrulle S, Baudouin C, Hidalgo-Figueroa M, Gow A, Glover JC, Tissir F, Clotman F, Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits. Sci Rep. 2020 Jan 22;10(1):996
1J:279607 Tonchev AB, Tuoc TC, Rosenthal EH, Studer M, Stoykova A, Zbtb20 modulates the sequential generation of neuronal layers in developing cortex. Mol Brain. 2016 Jun 9;9(1):65
3J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588
2J:306234 Tsai WL, Chang CJ, Wang CY, Hsu TI, Chang MY, Wu YH, Chang PS, Lin KL, Chuang JY, Kania A, Kao TJ, Paxillin Is Required for Proper Spinal Motor Axon Growth into the Limb. J Neurosci. 2021 Apr 28;41(17):3808-3821
1J:182758 Tschopp P, Christen AJ, Duboule D, Bimodal control of Hoxd gene transcription in the spinal cord defines two regulatory subclusters. Development. 2012 Mar;139(5):929-39
1*J:322228 Tsou YS, Wang CY, Chang MY, Hsu TI, Wu MT, Wu YH, Tsai WL, Chuang JY, Kao TJ, Vav2 is required for Netrin-1 receptor-class-specific spinal motor axon guidance. Dev Dyn. 2022 Mar;251(3):444-458
4J:282827 Tulloch AJ, Teo S, Carvajal BV, Tessier-Lavigne M, Jaworski A, Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3(Cre) mouse. J Comp Neurol. 2019 Dec 15;527(18):2948-2972
1J:225175 Turcatel G, Rubin N, Menke DB, Martin G, Shi W, Warburton D, Lung mesenchymal expression of Sox9 plays a critical role in tracheal development. BMC Biol. 2013;11:117
5J:260447 Usui N, Araujo DJ, Kulkarni A, Co M, Ellegood J, Harper M, Toriumi K, Lerch JP, Konopka G, Foxp1 regulation of neonatal vocalizations via cortical development. Genes Dev. 2017 Oct 15;31(20):2039-2055
3J:323057 Verdile V, Svetoni F, La Rosa P, Ferrante G, Cesari E, Sette C, Paronetto MP, EWS splicing regulation contributes to balancing Foxp1 isoforms required for neuronal differentiation. Nucleic Acids Res. 2022 Apr 8;50(6):3362-3378
2J:332242 Vieira JR, Shah B, Dupraz S, Paredes I, Himmels P, Schermann G, Adler H, Motta A, Gartner L, Navarro-Aragall A, Ioannou E, Dyukova E, Bonnavion R, Fischer A, Bonanomi D, Bradke F, Ruhrberg C, Ruiz de Almodovar C, Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development. Neuron. 2022 Dec 21;110(24):4074-4089.e6
1*J:251629 Waclaw RR, Ehrman LA, Merchan-Sala P, Kohli V, Nardini D, Campbell K, Foxo1 is a downstream effector of Isl1 in direct pathway striatal projection neuron development within the embryonic mouse telencephalon. Mol Cell Neurosci. 2017 Apr;80:44-51
1*J:92057 Waclaw RR, Wang B, Campbell K, The homeobox gene Gsh2 is required for retinoid production in the embryonic mouse telencephalon. Development. 2004 Aug;131(16):4013-20
1J:154936 Waclaw RR, Wang B, Pei Z, Ehrman LA, Campbell K, Distinct temporal requirements for the homeobox gene Gsx2 in specifying striatal and olfactory bulb neuronal fates. Neuron. 2009 Aug 27;63(4):451-65
1J:147161 Wang B, Waclaw RR, Allen ZJ 2nd, Guillemot F, Campbell K, Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon. Neural Dev. 2009;4:5
5J:93182 Wang B, Weidenfeld J, Lu MM, Maika S, Kuziel WA, Morrisey EE, Tucker PW, Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation. Development. 2004 Sep;131(18):4477-87
1J:339243 Wang J, Wang A, Tian K, Hua X, Zhang B, Zheng Y, Kong X, Li W, Xu L, Wang J, Li Z, Liu Y, Zhou Y, A Ctnnb1 enhancer regulates neocortical neurogenesis by controlling the abundance of intermediate progenitors. Cell Discov. 2022 Aug 2;8(1):74
2J:306250 Wang W, Cho H, Kim D, Park Y, Moon JH, Lim SJ, Yoon SM, McCane M, Aicher SA, Kim S, Emery B, Lee JW, Lee S, Park Y, Lee SK, PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway. Cell Rep. 2020 Sep 15;32(11):108147
4J:321501 Wang W, Cho H, Lee JW, Lee SK, The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development. Nat Commun. 2022 Feb 17;13(1):958
1*J:325555 Wang Y, Herzig G, Molano C, Liu A, Differential expression of the Tmem132 family genes in the developing mouse nervous system. Gene Expr Patterns. 2022 Jun 8;45:119257
2J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744
5*J:278092 Weng JS, Nakamura T, Moriizumi H, Takano H, Yao R, Takekawa M, MCRIP1 promotes the expression of lung-surfactant proteins in mice by disrupting CtBP-mediated epigenetic gene silencing. Commun Biol. 2019;2:227
2J:105897 Wijchers PJ, Hoekman MF, Burbach JP, Smidt MP, Identification of forkhead transcription factors in cortical and dopaminergic areas of the adult murine brain. Brain Res. 2006 Jan 12;1068(1):23-33
1J:212272 Wu J, Bao J, Kim M, Yuan S, Tang C, Zheng H, Mastick GS, Xu C, Yan W, Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):E2851-7
1J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456
1*J:224892 Yan Y, Wladyka C, Fujii J, Sockanathan S, Prdx4 is a compartment-specific H2O2 sensor that regulates neurogenesis by controlling surface expression of GDE2. Nat Commun. 2015;6:7006
1J:290593 Yen YP, Hsieh WF, Tsai YY, Lu YL, Liau ES, Hsu HC, Chen YC, Liu TC, Chang M, Li J, Lin SP, Hung JH, Chen JA, Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity. Elife. 2018 Oct 12;7:e38080
1J:321577 Yin W, Liontos A, Koepke J, Ghoul M, Mazzocchi L, Liu X, Lu C, Wu H, Fysikopoulos A, Sountoulidis A, Seeger W, Ruppert C, Gunther A, Stainier DYR, Samakovlis C, An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea. Development. 2022 Feb 1;149(3):dev199804
1J:183998 Yip DJ, Corcoran CP, Alvarez-Saavedra M, DeMaria A, Rennick S, Mears AJ, Rudnicki MA, Messier C, Picketts DJ, Snf2l regulates Foxg1-dependent progenitor cell expansion in the developing brain. Dev Cell. 2012 Apr 17;22(4):871-8
3*J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
4J:334713 Zhang J, Roberts JM, Chang F, Schwakopf J, Vetter ML, Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1. Cell Rep. 2023 Mar 28;42(3):112237
3J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44
1J:163662 Zhang Y, Li S, Yuan L, Tian Y, Weidenfeld J, Yang J, Liu F, Chokas AL, Morrisey EE, Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms. Genes Dev. 2010 Aug 15;24(16):1746-57
2J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055
4J:218833 Zhao H, Zhou W, Yao Z, Wan Y, Cao J, Zhang L, Zhao J, Li H, Zhou R, Li B, Wei G, Zhang Z, French CA, Dekker JD, Yang Y, Fisher SE, Tucker HO, Guo X, Foxp1/2/4 regulate endochondral ossification as a suppresser complex. Dev Biol. 2015 Feb 15;398(2):242-54

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory