About   Help   FAQ
Gene Expression Literature Summary
Symbol
Name
ID
Ncstn
nicastrin
MGI:1891700

7 matching records from 7 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E8.5 E9.5 E10.5 E14 E15 E15.5 E16 A
In situ protein (section) 2
In situ RNA (whole mount) 1 1 1 1
Northern blot 1
Western blot 2 1 2 3
RT-PCR 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Ncstn  nicastrin   (Synonyms: 9430068N19Rik, D1Dau13e, mKIAA0253, Nct, nicastrin)
Results  Reference
3J:97674 Culvenor JG, Ilaya NT, Ryan MT, Canterford L, Hoke DE, Williamson NA, McLean CA, Masters CL, Evin G, Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations. Eur J Biochem. 2004 Jan;271(2):375-85
5*J:68343 Doudney K, Murdoch JN, Paternotte C, Bentley L, Gregory S, Copp AJ, Stanier P, Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23. Genomics. 2001 Mar 1;72(2):180-92
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
4J:93286 Ilaya NT, Evin G, Masters CL, Culvenor JG, Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle. J Neurochem. 2004 Nov;91(1):230-7
2J:85205 Li J, Fici GJ, Mao CA, Myers RL, Shuang R, Donoho GP, Pauley AM, Himes CS, Qin W, Kola I, Merchant KM, Nye JS, Positive and negative regulation of the gamma-secretase activity by nicastrin in a murine model. J Biol Chem. 2003 Aug 29;278(35):33445-9
1J:63697 Underhill DA, Vogan KJ, Kibar Z, Morrison J, Rommens J, Gros P, Transcription mapping and expression analysis of candidate genes in the vicinity of the mouse Loop-tail mutation. Mamm Genome. 2000 Aug;11(8):633-8
3J:138527 Vetrivel KS, Zhang X, Meckler X, Cheng H, Lee S, Gong P, Lopes KO, Chen Y, Iwata N, Yin KJ, Lee JM, Parent AT, Saido TC, Li YM, Sisodia SS, Thinakaran G, Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta. J Biol Chem. 2008 Jul 11;283(28):19489-98

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/08/2014
MGI 5.17
The Jackson Laboratory