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Gene Expression Literature Summary
Symbol
Name
ID
Sptbn4
spectrin beta, non-erythrocytic 4
MGI:1890574

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7 E9.5 E10.5 E11.5 E12.5 E13.5 E15 E15.5 E18.5 E19 E20 P
Immunohistochemistry (section) 1 1 1 1 1 6
In situ RNA (section) 1 1 1 1 1
Immunohistochemistry (whole mount) 1
In situ RNA (whole mount) 1
Northern blot 1
Western blot 1 1 3
RT-PCR 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Sptbn4  spectrin beta, non-erythrocytic 4   (Synonyms: 1700022P15Rik, 5830426A08Rik, dyn, neuroaxonal dystrophy, nmf261, ROSA62, SpbIV, Spnb4)
Results  Reference
2J:300939 Jamann N, Dannehl D, Lehmann N, Wagener R, Thielemann C, Schultz C, Staiger J, Kole MHP, Engelhardt M, Sensory input drives rapid homeostatic scaling of the axon initial segment in mouse barrel cortex. Nat Commun. 2021 Jan 4;12(1):23
1J:332233 Kurki SN, Uvarov P, Pospelov AS, Trontti K, Hubner AK, Srinivasan R, Watanabe M, Hovatta I, Hubner CA, Kaila K, Virtanen MA, Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development. Cereb Cortex. 2022 Dec 27;
4J:93411 Lacas-Gervais S, Guo J, Strenzke N, Scarfone E, Kolpe M, Jahkel M, De Camilli P, Moser T, Rasband MN, Solimena M, BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments. J Cell Biol. 2004 Oct 27;166(7):983-90
4*J:214712 Le Bras B, Freal A, Czarnecki A, Legendre P, Bullier E, Komada M, Brophy PJ, Davenne M, Couraud F, In vivo assembly of the axon initial segment in motor neurons. Brain Struct Funct. 2014 Jul;219(4):1433-50
2J:142574 Legendre K, Safieddine S, Kussel-Andermann P, Petit C, El-Amraoui A, alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells. J Cell Sci. 2008 Oct 15;121(Pt 20):3347-56
1J:175548 Maddala R, Skiba NP, Lalane R 3rd, Sherman DL, Brophy PJ, Rao PV, Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers. Dev Biol. 2011 Sep 1;357(1):179-90
2J:304965 Miazek A, Zalas M, Skrzymowska J, Bogin BA, Grzymajlo K, Goszczynski TM, Levine ZA, Morrow JS, Stankewich MC, Age-dependent ataxia and neurodegeneration caused by an alphaII spectrin mutation with impaired regulation of its calpain sensitivity. Sci Rep. 2021 Mar 31;11(1):7312
5*J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
4*J:63322 Tse WT, Tang J, Jin O, Korsgren C, John KM, Kung AL, Gwynn B, Peters LL, Lux SE, A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix. J Biol Chem. 2001 Jun 29;276(26):23974-85
1J:219896 Zhang A, Desmazieres A, Zonta B, Melrose S, Campbell G, Mahad D, Li Q, Sherman DL, Reynolds R, Brophy PJ, Neurofascin 140 is an embryonic neuronal neurofascin isoform that promotes the assembly of the node of Ranvier. J Neurosci. 2015 Feb 4;35(5):2246-54

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory