Gene Expression Literature Summary

• Symbol: Tssc4
• Name: tumor-suppressing subchromosomal transferable fragment 4
• ID: MGI:1861712

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E4	E7.5	E9.5	E10.5	E11.5	E12.5	E13.5	E15.5	E16.5	E17	E	P
Northern blot											1
RT-PCR	1	1	4	2	2	1	2	1	1	1	1	9
cDNA clones												1
RNase protection					1		1					1
Primer Extension							1	1				3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tssc4  tumor-suppressing subchromosomal transferable fragment 4   (Synonyms: ESTM671070)
Results	Reference
2	J:10529 Bastian H, Gruss P, A murine even-skipped homologue, Evx 1, is expressed during early embryogenesis and neurogenesis in a biphasic manner [published erratum appears in EMBO J 1991 Dec;10(12):3978]. EMBO J. 1990 Jun;9(6):1839-52
2	J:266304 Bogutz AB, Oh-McGinnis R, Jacob KJ, Ho-Lau R, Gu T, Gertsenstein M, Nagy A, Lefebvre L, Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage. PLoS Genet. 2018 Aug;14(8):e1007587
2*	J:96366 Cerrato F, Sparago A, Di Matteo I, Zou X, Dean W, Sasaki H, Smith P, Genesio R, Bruggemann M, Reik W, Riccio A, The two-domain hypothesis in Beckwith-Wiedemann syndrome: autonomous imprinting of the telomeric domain of the distal chromosome 7 cluster. Hum Mol Genet. 2005 Feb 15;14(4):503-11
2	J:79882 Fitzpatrick GV, Soloway PD, Higgins MJ, Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1. Nat Genet. 2002 Nov;32(3):426-31
1*	J:118209 Green K, Lewis A, Dawson C, Dean W, Reinhart B, Chaillet JR, Reik W, A developmental window of opportunity for imprinted gene silencing mediated by DNA methylation and the Kcnq1ot1 noncoding RNA. Mamm Genome. 2007 Jan;18(1):32-42
3	J:114401 Lewis A, Green K, Dawson C, Redrup L, Huynh KD, Lee JT, Hemberger M, Reik W, Epigenetic dynamics of the Kcnq1 imprinted domain in the early embryo. Development. 2006 Nov;133(21):4203-10
3	J:94246 Lewis A, Mitsuya K, Umlauf D, Smith P, Dean W, Walter J, Higgins M, Feil R, Reik W, Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation. Nat Genet. 2004 Dec;36(12):1291-5
5	J:108700 Mancini-Dinardo D, Steele SJ, Levorse JM, Ingram RS, Tilghman SM, Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes. Genes Dev. 2006 May 15;20(10):1268-82
3	J:163857 Mohammad F, Mondal T, Guseva N, Pandey GK, Kanduri C, Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1. Development. 2010 Aug 1;137(15):2493-9
2	J:161410 Oh-McGinnis R, Bogutz AB, Lee KY, Higgins MJ, Lefebvre L, Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome. BMC Dev Biol. 2010;10:50
2	J:170637 Oh-McGinnis R, Bogutz AB, Lefebvre L, Partial loss of Ascl2 function affects all three layers of the mature placenta and causes intrauterine growth restriction. Dev Biol. 2011 Mar 15;351(2):277-86
5*	J:63702 Paulsen M, El-Maarri O, Engemann S, Strodicke M, Franck O, Davies K, Reinhardt R, Reik W, Walter J, Sequence conservation and variability of imprinting in the beckwith-wiedemann syndrome gene cluster in human and mouse. Hum Mol Genet. 2000 Jul 22;9(12):1829-41
1	J:130529 Shin JY, Fitzpatrick GV, Higgins MJ, Two distinct mechanisms of silencing by the KvDMR1 imprinting control region. EMBO J. 2008 Jan 9;27(1):168-78
3*	J:94241 Umlauf D, Goto Y, Cao R, Cerqueira F, Wagschal A, Zhang Y, Feil R, Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes. Nat Genet. 2004 Dec;36(12):1296-300