Gene Expression Literature Summary

• Symbol: Gdf15
• Name: growth differentiation factor 15
• ID: MGI:1346047

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E11.5	E12	E13.5	E14	E14.5	E15.5	E16	E16.5	E17.5	E18	E18.5	P
Immunohistochemistry (section)									1			3
In situ RNA (section)	1		1		1	2		1	1		2	2
In situ reporter (knock in)												1
Western blot						1						1
RT-PCR	1	1		2	2	1	2	2	3	2	2	5

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gdf15  growth differentiation factor 15   (Synonyms: macrophage inhibiting cytokine-1, MIC-1, NAG-1)
Results	Reference
1	J:346054 Baur K, Carrillo-Garcia C, San S, von Hahn M, Strelau J, Holzl-Wenig G, Mandl C, Ciccolini F, Growth/differentiation factor 15 controls ependymal and stem cell number in the V-SVZ. Stem Cell Reports. 2024 Mar 12;19(3):351-365
2	J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413
2*	J:57452 Bottner M, Laaff M, Schechinger B, Rappold G, Unsicker K, Suter-Crazzolara C, Characterization of the rat, mouse, and human genes of growth/differentiation factor-15/ macrophage inhibiting cytokine-1 (GDF-15/MIC-1). Gene. 1999 Sep 3;237(1):105-11
5	J:221296 Carrillo-Garcia C, Prochnow S, Simeonova IK, Strelau J, Holzl-Wenig G, Mandl C, Unsicker K, von Bohlen Und Halbach O, Ciccolini F, Growth/differentiation factor 15 promotes EGFR signalling, and regulates proliferation and migration in the hippocampus of neonatal and young adult mice. Development. 2014 Feb;141(4):773-83
4	J:294396 Chang KC, Sun C, Cameron EG, Madaan A, Wu S, Xia X, Zhang X, Tenerelli K, Nahmou M, Knasel CM, Russano KR, Hertz J, Goldberg JL, Opposing Effects of Growth and Differentiation Factors in Cell-Fate Specification. Curr Biol. 2019 Jun 17;29(12):1963-1975.e5
1	J:300508 Hilliard SA, Li Y, Dixon A, El-Dahr SS, Mdm4 controls ureteric bud branching via regulation of p53 activity. Mech Dev. 2020 Sep;163:103616
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
16	J:119728 Noorali S, Kurita T, Woolcock B, de Algara TR, Lo M, Paralkar V, Hoodless P, Vielkind J, Dynamics of expression of growth differentiation factor 15 in normal and PIN development in the mouse. Differentiation. 2007 Apr;75(4):325-36
2*	J:108109 Oxburgh L, Chu GC, Michael SK, Robertson EJ, TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development. 2004 Sep;131(18):4593-605
1	J:240000 Park JY, Hughes LJ, Moon UY, Park R, Kim SB, Tran K, Lee JS, Cho SH, Kim S, The apical complex protein Pals1 is required to maintain cerebellar progenitor cells in a proliferative state. Development. 2016 Jan 01;143(1):133-46
1	J:278252 Romaine A, Sorensen IW, Zeltz C, Lu N, Erusappan PM, Melleby AO, Zhang L, Bendiksen B, Robinson EL, Aronsen JM, Herum KM, Danielsen HE, Sjaastad I, Christensen G, Gullberg D, Overexpression of integrin alpha11 induces cardiac fibrosis in mice. Acta Physiol (Oxf). 2018 Feb;222(2)
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23