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Gene Expression Literature Summary
hairy/enhancer-of-split related with YRPW motif 2

112 matching records from 112 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7.5 E8 E8.5 E9 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14.5 E15 E15.5 E16.5 E17 E17.5 E18.5 E19.5 E A
In situ protein (section) 1 2 2
In situ RNA (section) 3 3 9 1 9 1 9 1 9 1 8 11 1 9 5 1 7 5 3 7
In situ RNA (whole mount) 2 4 3 12 1 5 3 1 1 1 1 1
In situ reporter (knock in) 1 1 1 1 1 1
Northern blot 1 1 1 1 1 2 1 1 1 1 1 5
Western blot 1
RT-PCR 2 6 13 5 3 1 7 1 4 6 1 3 5 2 3 4 1 1 13
cDNA clones 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Hey2  hairy/enhancer-of-split related with YRPW motif 2   (Synonyms: bHLHb32, CHF1, Herp1, Hesr2, Hrt2)
Results  Reference
1*J:102528 Barsi JC, Rajendra R, Wu JI, Artzt K, Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling. Mech Dev. 2005 Oct;122(10):1106-17
6J:173382 Basch ML, Ohyama T, Segil N, Groves AK, Canonical Notch Signaling Is Not Necessary for Prosensory Induction in the Mouse Cochlea: Insights from a Conditional Mutant of RBPj{kappa}. J Neurosci. 2011 Jun 1;31(22):8046-58
1J:145172 Benedito R, Trindade A, Hirashima M, Henrique D, da Costa LL, Rossant J, Gill PS, Duarte A, Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli. BMC Dev Biol. 2008;8:117
1J:72325 Bessho Y, Sakata R, Komatsu S, Shiota K, Yamada S, Kageyama R, Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev. 2001 Oct 15;15(20):2642-7
1J:175788 Bolte C, Zhang Y, Wang IC, Kalin TV, Molkentin JD, Kalinichenko VV, Expression of Foxm1 transcription factor in cardiomyocytes is required for myocardial development. PLoS One. 2011;6(7):e22217
2J:185338 Boucherat O, Chakir J, Jeannotte L, The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways. Biol Open. 2012;q:677-691
1J:202792 Boucherat O, Montaron S, Berube-Simard FA, Aubin J, Philippidou P, Wellik DM, Dasen JS, Jeannotte L, Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis. Am J Physiol Lung Cell Mol Physiol. 2013 Jun 15;304(12):L817-30
3J:213278 Boukens BJ, Sylva M, de Gier-de Vries C, Remme CA, Bezzina CR, Christoffels VM, Coronel R, Reduced sodium channel function unmasks residual embryonic slow conduction in the adult right ventricular outflow tract. Circ Res. 2013 Jul 5;113(2):137-41
1J:71845 Bruneau BG, Nemer G, Schmitt JP, Charron F, Robitaille L, Caron S, Conner DA, Gessler M, Nemer M, Seidman CE, Seidman JG, A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell. 2001 Sep 21;106(6):709-21
1J:199162 Cai T, Seymour ML, Zhang H, Pereira FA, Groves AK, Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti. J Neurosci. 2013 Jun 12;33(24):10110-22
1J:178530 Cai X, Nomura-Kitabayashi A, Cai W, Yan J, Christoffels VM, Cai CL, Myocardial Tbx20 regulates early atrioventricular canal formation and endocardial epithelial-mesenchymal transition via Bmp2. Dev Biol. 2011 Dec 15;360(2):381-90
2J:161794 Catela C, Kratsios P, Hede M, Lang F, Rosenthal N, Serum and glucocorticoid-inducible kinase 1 (SGK1) is necessary for vascular remodeling during angiogenesis. Dev Dyn. 2010 Jun 21;
2J:151951 Chen H, Ko G, Zatti A, Di Giacomo G, Liu L, Raiteri E, Perucco E, Collesi C, Min W, Zeiss C, De Camilli P, Cremona O, Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13838-43
2J:195489 Chen H, Zhang W, Sun X, Yoshimoto M, Chen Z, Zhu W, Liu J, Shen Y, Yong W, Li D, Zhang J, Lin Y, Li B, Vandusen NJ, Snider P, Schwartz RJ, Conway SJ, Field LJ, Yoder MC, Firulli AB, Carlesso N, Towbin JA, Shou W, Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity. Development. 2013 May;140(9):1946-57
3J:97734 Chen L, Al-Awqati Q, Segmental expression of Notch and Hairy genes in nephrogenesis. Am J Physiol Renal Physiol. 2005 May;288(5):F939-52
1J:185237 Chen L, Ma Y, Kim EY, Yu W, Schwartz RJ, Qian L, Wang J, Conditional ablation of Ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival. PLoS One. 2012;7(2):e31005
19*J:60859 Chin MT, Maemura K, Fukumoto S, Jain MK, Layne MD, Watanabe M, Hsieh CM, Lee ME, Cardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular system. J Biol Chem. 2000 Mar 3;275(9):6381-7
1J:205488 Chin SS, Romano RA, Nagarajan P, Sinha S, Garrett-Sinha LA, Aberrant epidermal differentiation and disrupted DeltaNp63/Notch regulatory axis in Ets1 transgenic mice. Biol Open. 2013;2(12):1336-45
3J:174608 Chong DC, Koo Y, Xu K, Fu S, Cleaver O, Stepwise arteriovenous fate acquisition during mammalian vasculogenesis. Dev Dyn. 2011 Jul 25;
1J:163848 Corada M, Nyqvist D, Orsenigo F, Caprini A, Giampietro C, Taketo MM, Iruela-Arispe ML, Adams RH, Dejana E, The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Dev Cell. 2010 Jun 15;18(6):938-49
5*J:152211 Coulpier F, Le Crom S, Maro GS, Manent J, Giovannini M, Maciorowski Z, Fischer A, Gessler M, Charnay P, Topilko P, Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers. Glia. 2009 Oct;57(13):1450-7
5J:178290 del Monte G, Casanova JC, Guadix JA, MacGrogan D, Burch JB, Perez-Pomares JM, de la Pompa JL, Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis. Circ Res. 2011 Apr 1;108(7):824-36
1J:124179 Del Monte G, Grego-Bessa J, Gonzalez-Rajal A, Bolos V, De La Pompa JL, Monitoring Notch1 activity in development: Evidence for a feedback regulatory loop. Dev Dyn. 2007 Sep;236(9):2594-614
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
5*J:79025 Donovan J, Kordylewska A, Jan Y, Utset M, Tetralogy of fallot and other congenital heart defects in hey2 mutant mice. Curr Biol. 2002 Sep 17;12(18):1605
2J:101349 Fischer A, Klattig J, Kneitz B, Diez H, Maier M, Holtmann B, Englert C, Gessler M, Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts. Mol Cell Biol. 2005 Oct;25(20):8960-70
2J:89444 Fischer A, Schumacher N, Maier M, Sendtner M, Gessler M, The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev. 2004 Apr 15;18(8):901-11
5J:133699 Fischer A, Steidl C, Wagner TU, Lang E, Jakob PM, Friedl P, Knobeloch KP, Gessler M, Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition. Circ Res. 2007 Mar 30;100(6):856-63
1J:140104 Franco CA, Mericskay M, Parlakian A, Gary-Bobo G, Gao-Li J, Paulin D, Gustafsson E, Li Z, Serum response factor is required for sprouting angiogenesis and vascular integrity. Dev Cell. 2008 Sep;15(3):448-61
1J:178310 Fukada S, Yamaguchi M, Kokubo H, Ogawa R, Uezumi A, Yoneda T, Matev MM, Motohashi N, Ito T, Zolkiewska A, Johnson RL, Saga Y, Miyagoe-Suzuki Y, Tsujikawa K, Takeda S, Yamamoto H, Hesr1 and Hesr3 are essential to generate undifferentiated quiescent satellite cells and to maintain satellite cell numbers. Development. 2011 Nov;138(21):4609-19
1J:160476 Ge C, Stanley P, Effects of varying Notch1 signal strength on embryogenesis and vasculogenesis in compound mutant heterozygotes. BMC Dev Biol. 2010;10:36
2J:79024 Gessler M, Knobeloch K, Helisch A, Amann K, Schumacher N, Rohde E, Fischer A, Leimeister C, Mouse gridlock. No Aortic Coarctation or Deficiency, but Fatal Cardiac Defects in Hey2 -/- Mice. Curr Biol. 2002 Sep 17;12(18):1601
1J:176609 Goldberg LB, Aujla PK, Raetzman LT, Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Dev Biol. 2011 Oct 1;358(1):23-32
1J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99
1*J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
2J:119151 Grego-Bessa J, Luna-Zurita L, del Monte G, Bolos V, Melgar P, Arandilla A, Garratt AN, Zang H, Mukouyama YS, Chen H, Shou W, Ballestar E, Esteller M, Rojas A, Perez-Pomares JM, de la Pompa JL, Notch signaling is essential for ventricular chamber development. Dev Cell. 2007 Mar;12(3):415-29
6J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23
5*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
5J:187652 Guo M, Zhang H, Bian F, Li G, Mu X, Wen J, Mao G, Teng Z, Xia G, Zhang M, P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis. Front Biosci (Elite Ed). 2012;4:2731-44
2J:96967 Hahn KL, Johnson J, Beres BJ, Howard S, Wilson-Rawls J, Lunatic fringe null female mice are infertile due to defects in meiotic maturation. Development. 2005 Feb;132(4):817-28
3*J:166749 Hammock EA, Eagleson KL, Barlow S, Earls LR, Miller DM 3rd, Levitt P, Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain. Neural Dev. 2010;5(1):32
6J:135657 Hayashi T, Kokubo H, Hartman BH, Ray CA, Reh TA, Bermingham-McDonogh O, Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea. Dev Biol. 2008 Apr 1;316(1):87-99
2J:118039 High FA, Zhang M, Proweller A, Tu L, Parmacek MS, Pear WS, Epstein JA, An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation. J Clin Invest. 2007 Feb 1;117(2):353-363
1J:199909 Im SK, Jeong H, Jeong HW, Kim KT, Hwang D, Ikegami M, Kong YY, Disruption of sorting nexin 5 causes respiratory failure associated with undifferentiated alveolar epithelial type I cells in mice. PLoS One. 2013;8(3):e58511
1J:139170 Imayoshi I, Shimogori T, Ohtsuka T, Kageyama R, Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development. 2008 Aug;135(15):2531-41
2J:186421 Klaus A, Muller M, Schulz H, Saga Y, Martin JF, Birchmeier W, Wnt/beta-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10921-6
5J:133798 Koibuchi N, Chin MT, CHF1/Hey2 plays a pivotal role in left ventricular maturation through suppression of ectopic atrial gene expression. Circ Res. 2007 Mar 30;100(6):850-5
2J:119923 Kokubo H, Tomita-Miyagawa S, Hamada Y, Saga Y, Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2. Development. 2007 Feb;134(4):747-55
2J:101173 Koo BK, Lim HS, Song R, Yoon MJ, Yoon KJ, Moon JS, Kim YW, Kwon MC, Yoo KW, Kong MP, Lee J, Chitnis AB, Kim CH, Kong YY, Mind bomb 1 is essential for generating functional Notch ligands to activate Notch. Development. 2005 Aug;132(15):3459-70
1J:170885 Kratsios P, Catela C, Salimova E, Huth M, Berno V, Rosenthal N, Mourkioti F, Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart. Circ Res. 2010 Feb 19;106(3):559-72
1J:164056 Kwon C, Arnold J, Hsiao EC, Taketo MM, Conklin BR, Srivastava D, Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):10894-9
1J:175663 Laforest B, Andelfinger G, Nemer M, Loss of Gata5 in mice leads to bicuspid aortic valve. J Clin Invest. 2011 Jul 1;121(7):2876-87
3J:65682 Leimeister C, Dale K, Fischer A, Klamt B, Hrabe de Angelis M, Radtke F, McGrew MJ, Pourquie O, Gessler M, Oscillating expression of c-hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors. Dev Biol. 2000 Nov 1;227(1):91-103
9*J:53397 Leimeister C, Externbrink A, Klamt B, Gessler M, Hey genes: a novel subfamily of hairy- and Enhancer of split related genes specifically expressed during mouse embryogenesis. Mech Dev. 1999 Jul;85(1-2):173-7
1*J:85874 Leimeister C, Schumacher N, Gessler M, Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development. Gene Expr Patterns. 2003 Oct;3(5):595-8
4J:135642 Li S, Mark S, Radde-Gallwitz K, Schlisner R, Chin MT, Chen P, Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development. BMC Dev Biol. 2008;8:20
1J:185603 Li S, Wang Y, Zhang Y, Lu MM, Demayo FJ, Dekker JD, Tucker PW, Morrisey EE, Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2. Development. 2012 Jul;139(14):2500-9
2J:165329 Luna-Zurita L, Prados B, Grego-Bessa J, Luxan G, del Monte G, Benguria A, Adams RH, Perez-Pomares JM, de la Pompa JL, Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation. J Clin Invest. 2010 Oct 1;120(10):3493-507
5J:195070 Luxan G, Casanova JC, Martinez-Poveda B, Prados B, D'Amato G, MacGrogan D, Gonzalez-Rajal A, Dobarro D, Torroja C, Martinez F, Izquierdo-Garcia JL, Fernandez-Friera L, Sabater-Molina M, Kong YY, Pizarro G, Ibanez B, Medrano C, Garcia-Pavia P, Gimeno JR,Monserrat L, Jimenez-Borreguero LJ, de la Pompa JL, Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nat Med. 2013 Feb;19(2):193-201
2J:145175 Maitra M, Schluterman MK, Nichols HA, Richardson JA, Lo CW, Srivastava D, Garg V, Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development. Dev Biol. 2009 Feb 15;326(2):368-77
1J:202909 Mansour SL, Li C, Urness LD, Genetic rescue of Muenke syndrome model hearing loss reveals prolonged FGF-dependent plasticity in cochlear supporting cell fates. Genes Dev. 2013 Nov 1;27(21):2320-31
1J:171254 Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI, Fbxw7-dependent Degradation of Notch Is Required for Control of 'Stemness' and Neuronal-Glial Differentiation in Neural Stem Cells. J Biol Chem. 2011 Apr 15;286(15):13754-64
1J:182904 Moran TB, Goldberg LB, Serviss SL, Raetzman LT, Numb deletion in POMC-expressing cells impairs pituitary intermediate lobe cell adhesion, progenitor cell localization, and neuro-intermediate lobe boundary formation. Mol Endocrinol. 2011 Jan;25(1):117-27
1J:153555 Mukhopadhyay A, Jarrett J, Chlon T, Kessler JA, HeyL regulates the number of TrkC neurons in dorsal root ganglia. Dev Biol. 2009 Oct 1;334(1):142-51
1J:192269 Mukhopadhyay A, Krishnaswami SR, Cowing-Zitron C, Hung NJ, Reilly-Rhoten H, Burns J, Yu BD, Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development. Dev Biol. 2013 Jan 15;373(2):373-82
3J:172692 Mysliwiec MR, Bresnick EH, Lee Y, Endothelial jarid2/jumonji is required for normal cardiac development and proper notch1 expression. J Biol Chem. 2011 May 13;286(19):17193-204
9*J:58781 Nakagawa O, Nakagawa M, Richardson JA, Olson EN, Srivastava D, HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. Dev Biol. 1999 Dec 1;216(1):72-84
1J:214133 Nantie LB, Himes AD, Getz DR, Raetzman LT, Notch signaling in postnatal pituitary expansion: proliferation, progenitors, and cell specification. Mol Endocrinol. 2014 May;28(5):731-44
1J:167379 Nichol D, Shawber C, Fitch MJ, Bambino K, Sharma A, Kitajewski J, Stuhlmann H, Impaired angiogenesis and altered Notch signaling in mice overexpressing endothelial Egfl7. Blood. 2010 Dec 23;116(26):6133-43
1J:154475 Nomura-Kitabayashi A, Anderson GA, Sleep G, Mena J, Karabegovic A, Karamath S, Letarte M, Puri MC, Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo. Dev Biol. 2009 Nov 1;335(1):66-77
1J:166455 Ohyama T, Basch ML, Mishina Y, Lyons KM, Segil N, Groves AK, BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea. J Neurosci. 2010 Nov 10;30(45):15044-51
1J:178680 Oyama T, Harigaya K, Sasaki N, Okamura Y, Kokubo H, Saga Y, Hozumi K, Suganami A, Tamura Y, Nagase T, Koga H, Nishimura M, Sakamoto R, Sato M, Yoshida N, Kitagawa M, Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo. Development. 2011 Dec;138(23):5235-46
1J:144980 Phng LK, Potente M, Leslie JD, Babbage J, Nyqvist D, Lobov I, Ondr JK, Rao S, Lang RA, Thurston G, Gerhardt H, Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis. Dev Cell. 2009 Jan;16(1):70-82
2*J:112456 Plageman TF Jr, Yutzey KE, Microarray analysis of Tbx5-induced genes expressed in the developing heart. Dev Dyn. 2006 Aug 7;235(10):2868-2880
1J:209193 Redeker C, Schuster-Gossler K, Kremmer E, Gossler A, Normal development in mice over-expressing the intracellular domain of DLL1 argues against reverse signaling by DLL1 in vivo. PLoS One. 2013;8(10):e79050
2J:97176 Robert-Moreno A, Espinosa L, de la Pompa JL, Bigas A, RBPj{kappa}-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells. Development. 2005 Mar;132(5):1117-26
1J:123174 Robert-Moreno A, Espinosa L, Sanchez MJ, de la Pompa JL, Bigas A, The notch pathway positively regulates programmed cell death during erythroid differentiation. Leukemia. 2007 Jul;21(7):1496-503
4J:86573 Sakamoto M, Hirata H, Ohtsuka T, Bessho Y, Kageyama R, The basic helix-loop-helix genes Hesr1/Hey1 and Hesr2/Hey2 regulate maintenance of neural precursor cells in the brain. J Biol Chem. 2003 Nov 7;278(45):44808-15
5J:109366 Satow T, Bae SK, Inoue T, Inoue C, Miyoshi G, Tomita K, Bessho Y, Hashimoto N, Kageyama R, The basic helix-loop-helix gene hesr2 promotes gliogenesis in mouse retina. J Neurosci. 2001 Feb 15;21(4):1265-73
1J:119144 Seo S, Fujita H, Nakano A, Kang M, Duarte A, Kume T, The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development. Dev Biol. 2006 Jun 15;294(2):458-70
1J:127386 Shawber CJ, Funahashi Y, Francisco E, Vorontchikhina M, Kitamura Y, Stowell SA, Borisenko V, Feirt N, Podgrabinska S, Shiraishi K, Chawengsaksophak K, Rossant J, Accili D, Skobe M, Kitajewski J, Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. J Clin Invest. 2007 Nov;117(11):3369-82
1J:98806 Singh MK, Christoffels VM, Dias JM, Trowe MO, Petry M, Schuster-Gossler K, Burger A, Ericson J, Kispert A, Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2. Development. 2005 Jun;132(12):2697-707
2J:186473 Somekawa S, Imagawa K, Hayashi H, Sakabe M, Ioka T, Sato GE, Inada K, Iwamoto T, Mori T, Uemura S, Nakagawa O, Saito Y, Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12064-9
1J:174237 Sripathy S, Lee M, Vasioukhin V, Mammalian Llgl2 Is Necessary for Proper Branching Morphogenesis during Placental Development. Mol Cell Biol. 2011 Jul;31(14):2920-33
2*J:62860 Steidl C, Leimeister C, Klamt B, Maier M, Nanda I, Dixon M, Clarke R, Schmid M, Gessler M, Characterization of the human and mouse HEY1, HEY2, and HEYL genes: cloning, mapping, and mutation screening of a new bHLH gene family. Genomics. 2000 Jun 1;66(2):195-203
2J:204446 Tateya T, Imayoshi I, Tateya I, Hamaguchi K, Torii H, Ito J, Kageyama R, Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea. Development. 2013 Sep;140(18):3848-57
1J:171468 Tateya T, Imayoshi I, Tateya I, Ito J, Kageyama R, Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development. Dev Biol. 2011 Apr 15;352(2):329-40
1J:187204 Thomas PS, Sridurongrit S, Ruiz-Lozano P, Kaartinen V, Deficient signaling via Alk2 (Acvr1) leads to bicuspid aortic valve development. PLoS One. 2012;7(4):e35539
3J:87765 Timmerman LA, Grego-Bessa J, Raya A, Bertran E, Perez-Pomares JM, Diez J, Aranda S, Palomo S, McCormick F, Izpisua-Belmonte JC, de la Pompa JL, Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes Dev. 2004 Jan 1;18(1):99-115
1J:155773 Tkatchenko TV, Moreno-Rodriguez RA, Conway SJ, Molkentin JD, Markwald RR, Tkatchenko AV, Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease. Physiol Genomics. 2009 Nov 6;39(3):160-8
2J:142471 Tsao PN, Chen F, Izvolsky KI, Walker J, Kukuruzinska MA, Lu J, Cardoso WV, Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung. J Biol Chem. 2008 Oct 24;283(43):29532-44
1J:150051 Tsao PN, Vasconcelos M, Izvolsky KI, Qian J, Lu J, Cardoso WV, Notch signaling controls the balance of ciliated and secretory cell fates in developing airways. Development. 2009 Jul;136(13):2297-307
1J:175774 Tsao PN, Wei SC, Wu MF, Huang MT, Lin HY, Lee MC, Lin KM, Wang IJ, Kaartinen V, Yang LT, Cardoso WV, Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development. Development. 2011 Aug;138(16):3533-43
1J:88517 Tsunematsu R, Nakayama K, Oike Y, Nishiyama M, Ishida N, Hatakeyama S, Bessho Y, Kageyama R, Suda T, Nakayama KI, Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development. J Biol Chem. 2004 Mar 5;279(10):9417-23
4J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26
1J:165022 Uchida K, Aramaki M, Nakazawa M, Yamagishi C, Makino S, Fukuda K, Nakamura T, Takahashi T, Mikoshiba K, Yamagishi H, Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis. PLoS One. 2010;5(9)
1J:152652 Venkatesh DA, Park KS, Harrington A, Miceli-Libby L, Yoon JK, Liaw L, Cardiovascular and hematopoietic defects associated with Notch1 activation in embryonic Tie2-expressing populations. Circ Res. 2008 Aug 15;103(4):423-31
1J:195264 Vincentz JW, Firulli BA, Lin A, Spicer DB, Howard MJ, Firulli AB, Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest. PLoS Genet. 2013 Mar;9(3):e1003405
1J:199879 Wang Y, Wu B, Chamberlain AA, Lui W, Koirala P, Susztak K, Klein D, Taylor V, Zhou B, Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development. PLoS One. 2013;8(4):e60244
2J:165754 Watanabe T, Koibuchi N, Chin MT, Transcription factor CHF1/Hey2 regulates coronary vascular maturation. Mech Dev. 2010 Sep-Dec;127(9-12):418-27
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