Gene Expression Literature Summary

• Symbol: Ndrg1
• Name: N-myc downstream regulated gene 1
• ID: MGI:1341799

32 matching records from 32 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1	E1.5	E2	E3	E3.5	E5.5	E6.5	E7.5	E8	E8.5	E9.5	E10	E10.5	E11.5	E12.5	E13.5	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)																												2
In situ RNA (section)							1	1					1	1	1	1	7			1	3				1			2
In situ RNA (whole mount)						1	1	1	1	3	2		4		1			1	2
In situ reporter (knock in)																												1
Northern blot											2		2	2	2	2			2				1
Western blot										1																		4
RT-PCR	1	1	2	1	1							1	1			1				1	1	1		1	1	1	2	3
cDNA clones							1						1			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ndrg1  N-myc downstream regulated gene 1   (Synonyms: CAP43, CMT4D, DRG1, Ndr1, Ndrl, PROXY1, Tdd5, TDD5)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
2*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
1	J:184511 Cohen ED, Miller MF, Wang Z, Moon RT, Morrisey EE, Wnt5a and Wnt11 are essential for second heart field progenitor development. Development. 2012 Jun;139(11):1931-40
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
6*	J:261876 Endo T, Nakamura J, Sato Y, Asada M, Yamada R, Takase M, Takaori K, Oguchi A, Iguchi T, Higashi AY, Ohbayashi T, Nakamura T, Muso E, Kimura T, Yanagita M, Exploring the origin and limitations of kidney regeneration. J Pathol. 2015 Jun;236(2):251-63
2*	J:211289 Fantauzzo KA, Soriano P, PI3K-mediated PDGFRalpha signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways. Genes Dev. 2014 May 1;28(9):1005-17
9*	J:120097 Frankenberg S, Smith L, Greenfield A, Zernicka-Goetz M, Novel gene expression patterns along the proximo-distal axis of the mouse embryo before gastrulation. BMC Dev Biol. 2007;7:8
1*	J:270507 Funato N, Yanagisawa H, Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans. Arch Oral Biol. 2018 Nov;95:149-155
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1	J:230653 Grego-Bessa J, Bloomekatz J, Castel P, Omelchenko T, Baselga J, Anderson KV, The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium. Elife. 2016;5:e12034
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:210222 Hupe M, Li MX, Gertow Gillner K, Adams RH, Stenman JM, Evaluation of TRAP-sequencing technology with a versatile conditional mouse model. Nucleic Acids Res. 2014 Jan;42(2):e14
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:131292 Li J, Ran C, Li E, Gordon F, Comstock G, Siddiqui H, Cleghorn W, Chen HZ, Kornacker K, Liu CG, Pandit SK, Khanizadeh M, Weinstein M, Leone G, de Bruin A, Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development. Dev Cell. 2008 Jan;14(1):62-75
4*	J:274867 Lim M, Brown HM, Kind KL, Breen J, Anastasi MR, Ritter LJ, Tregoweth EK, Dinh DT, Thompson JG, Dunning KR, Haemoglobin expression in in vivo murine preimplantation embryos suggests a role in oxygen-regulated gene expression. Reprod Fertil Dev. 2019 Apr;31(4):724-734
2*	J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13
1*	J:270210 Loo L, Simon JM, Xing L, McCoy ES, Niehaus JK, Guo J, Anton ES, Zylka MJ, Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun. 2019 Jan 11;10(1):134
3*	J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676
1*	J:119126 Miyata K, Yasukawa T, Fukuda M, Takeuchi T, Yamazaki K, Sakumi K, Tamamori-Adachi M, Ohnishi Y, Ohtsuki Y, Nakabeppu Y, Kitajima S, Onishi S, Aso T, Induction of apoptosis and cellular senescence in mice lacking transcription elongation factor, Elongin A. Cell Death Differ. 2007 Apr;14(4):716-26
1*	J:332746 Navas-Perez E, Vicente-Garcia C, Mirra S, Burguera D, Fernandez-Castillo N, Ferran JL, Lopez-Mayorga M, Alaiz-Noya M, Suarez-Pereira I, Anton-Galindo E, Ulloa F, Herrera-Ubeda C, Cusco P, Falcon-Moya R, Rodriguez-Moreno A, D'Aniello S, Cormand B, Marfany G, Soriano E, Carrion AM, Carvajal JJ, Garcia-Fernandez J, Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions. Genome Biol. 2020 Oct 26;21(1):267
10*	J:58924 Okuda T, Kondoh H, Identification of new genes ndr2 and ndr3 which are related to Ndr1/RTP/Drg1 but show distinct tissue specificity and response to N-myc. Biochem Biophys Res Commun. 1999 Dec 9;266(1):208-15
1	J:183999 Ouseph MM, Li J, Chen HZ, Pecot T, Wenzel P, Thompson JC, Comstock G, Chokshi V, Byrne M, Forde B, Chong JL, Huang K, Machiraju R, de Bruin A, Leone G, Atypical E2F repressors and activators coordinate placental development. Dev Cell. 2012 Apr 17;22(4):849-62
1	J:269511 Roy A, Skibo J, Kalume F, Ni J, Rankin S, Lu Y, Dobyns WB, Mills GB, Zhao JJ, Baker SJ, Millen KJ, Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy. Elife. 2015 Dec 3;4:e12703
2	J:243030 Schmitz-Rohmer D, Probst S, Yang ZZ, Laurent F, Stadler MB, Zuniga A, Zeller R, Hynx D, Hemmings BA, Hergovich A, NDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic Development. PLoS One. 2015;10(8):e0136566
13*	J:56022 Shimono A, Okuda T, Kondoh H, N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant. Mech Dev. 1999 May;83(1-2):39-52
2*	J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46
1*	J:143778 Tamplin OJ, Cox BJ, Rossant J, Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Dev Biol. 2011 Dec 15;360(2):415-25
1	J:152884 Tanaka M, Endo S, Okuda T, Economides AN, Valenzuela DM, Murphy AJ, Robertson E, Sakurai T, Fukatsu A, Yancopoulos GD, Kita T, Yanagita M, Expression of BMP-7 and USAG-1 (a BMP antagonist) in kidney development and injury. Kidney Int. 2008 Jan;73(2):181-91
2*	J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
1*	J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
2	J:227211 Zhang Y, Li F, Wang Y, Pitre A, Fang ZZ, Frank MW, Calabrese C, Krausz KW, Neale G, Frase S, Vogel P, Rock CO, Gonzalez FJ, Schuetz JD, Maternal bile acid transporter deficiency promotes neonatal demise. Nat Commun. 2015;6:8186
1*	J:315254 Zurashvili T, Cordon-Barris L, Ruiz-Babot G, Zhou X, Lizcano JM, Gomez N, Gimenez-Llort L, Bayascas JR, Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival. Mol Cell Biol. 2013 Mar;33(5):1027-40