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Gene Expression Literature Summary
Symbol
Name
ID
Parp1
poly (ADP-ribose) polymerase family, member 1
MGI:1340806

45 matching records from 45 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E5.5 E7.5 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13.5 E14.5 E16.5 E17.5 E18 E18.5 E19.5 E20 E P
Immunohistochemistry (section) 2 1 3 1 2 1 1 6 2 1 2 1 1 9
In situ RNA (section) 1 2 2 1 2 1 2
Immunohistochemistry (whole mount) 1 1
Western blot 1 1 1 1 2 3 1 1 2 7
RT-PCR 2 2
cDNA clones 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Parp1  poly (ADP-ribose) polymerase family, member 1   (Synonyms: 5830444G22Rik, Adprp, Adprt1, PARP, parp-1, sPARP-1)
Results  Reference
1J:264269 Azimi M, Le TT, Brown NL, Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens. Differentiation. 2018 Jul - Aug;102:40-52
1J:191131 Chen L, Faire M, Kissner MD, Laird DJ, Primordial germ cells and gastrointestinal stromal tumors respond distinctly to a cKit overactivating allele. Hum Mol Genet. 2013 Jan 15;22(2):313-27
1J:230030 Cheng IC, Chen BC, Shuai HH, Chien FC, Chen P, Hsieh TS, Wuho Is a New Member in Maintaining Genome Stability through its Interaction with Flap Endonuclease 1. PLoS Biol. 2016 Jan;14(1):e1002349
1J:173089 Daniel K, Lange J, Hached K, Fu J, Anastassiadis K, Roig I, Cooke HJ, Stewart AF, Wassmann K, Jasin M, Keeney S, Toth A, Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol. 2011 May;13(5):599-610
1J:119857 Desmots F, Russell HR, Lee Y, Boyd K, McKinnon PJ, The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development. Mol Cell Biol. 2005 Dec;25(23):10329-37
2J:162165 Dudley B, Palumbo C, Nalepka J, Molyneaux K, BMP signaling controls formation of a primordial germ cell niche within the early genital ridges. Dev Biol. 2010 Jul 1;343(1-2):84-93
1J:265712 Dziedzic SA, Su Z, Jean Barrett V, Najafov A, Mookhtiar AK, Amin P, Pan H, Sun L, Zhu H, Ma A, Abbott DW, Yuan J, ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC. Nat Cell Biol. 2018 Jan;20(1):58-68
4J:196310 Ene AC, Park S, Edelmann W, Taketo T, Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Dev Biol. 2013 May 1;377(1):213-23
1J:253771 Gaudreau MC, Grapton D, Helness A, Vadnais C, Fraszczak J, Shooshtarizadeh P, Wilhelm B, Robert F, Heyd F, Moroy T, Heterogeneous Nuclear Ribonucleoprotein L is required for the survival and functional integrity of murine hematopoietic stem cells. Sci Rep. 2016 Jun 7;6:27379
1*J:217689 Guzman-Ayala M, Sachs M, Koh FM, Onodera C, Bulut-Karslioglu A, Lin CJ, Wong P, Nitta R, Song JS, Ramalho-Santos M, Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast. Development. 2015 Jan 1;142(1):118-27
1J:161356 Hajkova P, Jeffries SJ, Lee C, Miller N, Jackson SP, Surani MA, Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science. 2010 Jul 2;329(5987):78-82
6*J:130337 Hakme A, Huber A, Dolle P, Schreiber V, The macroPARP genes Parp-9 and Parp-14 are developmentally and differentially regulated in mouse tissues. Dev Dyn. 2008 Jan;237(1):209-15
2J:162637 Hang CT, Yang J, Han P, Cheng HL, Shang C, Ashley E, Zhou B, Chang CP, Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature. 2010 Jul 1;466(7302):62-7
1J:207609 Hilliard SA, Yao X, El-Dahr SS, Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014 Mar 1;387(1):1-14
1J:248708 Hoffmeister M, Krieg J, Ehrke A, Seigfried FA, Wischmann L, Dietmann P, Kuhl SJ, Oess S, Developmental neurogenesis in mouse and Xenopus is impaired in the absence of Nosip. Dev Biol. 2017 Sep 1;429(1):200-212
2J:69602 Hohenstein P, Kielman MF, Breukel C, Bennett LM, Wiseman R, Krimpenfort P, Cornelisse C, van Ommen GJ, Devilee P, Fodde R, A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage. Oncogene. 2001 May 3;20(20):2544-50
1J:162581 Huillard E, Ziercher L, Blond O, Wong M, Deloulme JC, Souchelnytskyi S, Baudier J, Cochet C, Buchou T, Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon. Mol Cell Biol. 2010 Jun;30(11):2737-49
1J:235787 Ijaz T, Wakamiya M, Sun H, Recinos A 3rd, Tilton RG, Brasier AR, Generation and characterization of a novel transgenic mouse harboring conditional nuclear factor-kappa B/RelA knockout alleles. BMC Dev Biol. 2016 Sep 23;16(1):32
1J:202252 Jones RL, Pepling ME, KIT signaling regulates primordial follicle formation in the neonatal mouse ovary. Dev Biol. 2013 Oct 1;382(1):186-97
1J:199673 Kleppa L, Mari PO, Larsen E, Lien GF, Godon C, Theil AF, Nesse GJ, Wiksen H, Vermeulen W, Giglia-Mari G, Klungland A, Kinetics of endogenous mouse FEN1 in base excision repair. Nucleic Acids Res. 2012 Oct;40(18):9044-59
1J:266268 Kowalchuk AM, Maurer KA, Shoja-Taheri F, Brown NL, Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis. Dev Biol. 2018 Oct 15;442(2):220-235
1J:179805 Laird DJ, Altshuler-Keylin S, Kissner MD, Zhou X, Anderson KV, Ror2 enhances polarity and directional migration of primordial germ cells. PLoS Genet. 2011 Dec;7(12):e1002428
1J:181272 Le TT, Conley KW, Mead TJ, Rowan S, Yutzey KE, Brown NL, Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. Dev Dyn. 2012 Mar;241(3):493-504
1J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137
1J:152528 Lee Y, Katyal S, Li Y, El-Khamisy SF, Russell HR, Caldecott KW, McKinnon PJ, The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1. Nat Neurosci. 2009 Aug;12(8):973-80
1*J:109158 Leu S, Ouyang P, Spatial and temporal expression profile of pinin during mouse development. Gene Expr Patterns. 2006 Aug;6(6):620-31
1J:268414 Liu Y, Fan C, Zhang Y, Yu X, Wu X, Zhang X, Zhao Q, Zhang H, Xie Q, Li M, Li X, Ding Q, Ying H, Li D, Zhang H, RIP1 kinase activity-dependent roles in embryonic development of Fadd-deficient mice. Cell Death Differ. 2017 Aug;24(8):1459-1469
1J:255932 Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun. 2017 Nov 28;8(1):1819
5*J:181599 Martin-Oliva D, Ferrer-Martin RM, Santos AM, Carrasco MC, Sierra A, Marin-Teva JL, Calvente R, Navascues J, Cuadros MA, Simultaneous cell death and upregulation of poly(ADP-ribose) polymerase-1 expression in early postnatal mouse retina. Invest Ophthalmol Vis Sci. 2011 Sep;52(10):7445-54
1J:184928 Miles DC, van den Bergen JA, Wakeling SI, Anderson RB, Sinclair AH, Western PS, The proto-oncogene Ret is required for male foetal germ cell survival. Dev Biol. 2012 May 1;365(1):101-9
2J:42726 Nakayama H, Liu Y, Stifani S, Cross JC, Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway. Dev Genet. 1997;21(1):21-30
2J:152672 Ohsawa S, Hamada S, Asou H, Kuida K, Uchiyama Y, Yoshida H, Miura M, Caspase-9 activation revealed by semaphorin 7A cleavage is independent of apoptosis in the aged olfactory bulb. J Neurosci. 2009 Sep 9;29(36):11385-92
1J:124128 Rajareddy S, Reddy P, Du C, Liu L, Jagarlamudi K, Tang W, Shen Y, Berthet C, Peng SL, Kaldis P, Liu K, p27kip1 (Cyclin-Dependent Kinase Inhibitor 1B) Controls Ovarian Development by Suppressing Follicle Endowment and Activation and Promoting Follicle Atresia in Mice. Mol Endocrinol. 2007 Sep;21(9):2189-202
2J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77
1J:115283 Runyan C, Schaible K, Molyneaux K, Wang Z, Levin L, Wylie C, Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration. Development. 2006 Dec;133(24):4861-9
1J:180791 Saravanamuthu SS, Le TT, Gao CY, Cojocaru RI, Pandiyan P, Liu C, Zhang J, Zelenka PS, Brown NL, Conditional ablation of the Notch2 receptor in the ocular lens. Dev Biol. 2012 Feb 15;362(2):219-29
5J:77259 Schreiber V, Ame JC, Dolle P, Schultz I, Rinaldi B, Fraulob V, Menissier-de Murcia J, de Murcia G, Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1. J Biol Chem. 2002 Jun 21;277(25):23028-36
2J:165253 Scott CE, Wynn SL, Sesay A, Cruz C, Cheung M, Gomez Gaviro MV, Booth S, Gao B, Cheah KS, Lovell-Badge R, Briscoe J, SOX9 induces and maintains neural stem cells. Nat Neurosci. 2010 Oct;13(10):1181-9
1J:234716 Segura I, Lange C, Knevels E, Moskalyuk A, Pulizzi R, Eelen G, Chaze T, Tudor C, Boulegue C, Holt M, Daelemans D, Matondo M, Ghesquiere B, Giugliano M, Ruiz de Almodovar C, Dewerchin M, Carmeliet P, The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A. Cell Rep. 2016 Mar 22;14(11):2653-67
1J:118190 Sugo N, Niimi N, Aratani Y, Masutani M, Suzuki H, Koyama H, Decreased PARP-1 levels accelerate embryonic lethality but attenuate neuronal apoptosis in DNA polymerase beta-deficient mice. Biochem Biophys Res Commun. 2007 Mar 16;354(3):656-61
1J:101924 Tang LS, Wlodarczyk BJ, Santillano DR, Miranda RC, Finnell RH, Developmental consequences of abnormal folate transport during murine heart morphogenesis. Birth Defects Res A Clin Mol Teratol. 2004 Jul;70(7):449-58
1J:144502 Taniguchi N, Carames B, Ronfani L, Ulmer U, Komiya S, Bianchi ME, Lotz M, Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis. Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1181-6
2*J:109514 Vats KR, Ishwad C, Singla I, Vats A, Ferrell R, Ellis D, Moritz M, Surti U, Jayakar P, Frederick DR, Vats AN, A locus for renal malformations including vesico-ureteric reflux on chromosome 13q33-34. J Am Soc Nephrol. 2006 Apr;17(4):1158-67
4J:115402 Vemuri MC, Schiller E, Naegele JR, Elevated DNA double strand breaks and apoptosis in the CNS of scid mutant mice. Cell Death Differ. 2001 Mar;8(3):245-55
1J:223139 Ye J, Beetz N, O'Keeffe S, Tapia JC, Macpherson L, Chen WV, Bassel-Duby R, Olson EN, Maniatis T, hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):E3020-9

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last database update
02/12/2019
MGI 6.13
The Jackson Laboratory