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Gene Expression Literature Summary
Symbol
Name
ID
Rnd2
Rho family GTPase 2
MGI:1338755

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E9.5 E11 E12.5 E13.5 E14 E14.5 E15.5 E16 E16.5 E17 E18 E18.5 E P
Immunohistochemistry (section) 1
In situ RNA (section) 3 3 1 5 2 4 1 2
In situ RNA (whole mount) 1
Western blot 1 1 2 1 1 1
RT-PCR 1 4 1 1 1 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Rnd2  Rho family GTPase 2   (Synonyms: Arhn, Rohn)
Results  Reference
6J:178862 Alfano C, Viola L, Heng JI, Pirozzi M, Clarkson M, Flore G, De Maio A, Schedl A, Guillemot F, Studer M, COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression. Development. 2011 Nov;138(21):4685-97
3J:114098 Armentano M, Filosa A, Andolfi G, Studer M, COUP-TFI is required for the formation of commissural projections in the forebrain by regulating axonal growth. Development. 2006 Nov;133(21):4151-62
1J:173570 Asprer JS, Lee B, Wu CS, Vadakkan T, Dickinson ME, Lu HC, Lee SK, LMO4 functions as a co-activator of neurogenin 2 in the developing cortex. Development. 2011 Jul;138(13):2823-32
3*J:225235 Azzarelli R, Pacary E, Garg R, Garcez P, van den Berg D, Riou P, Ridley AJ, Friedel RH, Parsons M, Guillemot F, An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration. Nat Commun. 2014;5:3405
3J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:262482 Dubos A, Meziane H, Iacono G, Curie A, Riet F, Martin C, Loaec N, Birling MC, Selloum M, Normand E, Pavlovic G, Sorg T, Stunnenberg HG, Chelly J, Humeau Y, Friocourt G, Herault Y, A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations. Hum Mol Genet. 2018 Jun 15;27(12):2138-2153
1J:241099 Flore G, Cioffi S, Bilio M, Illingworth E, Cortical Development Requires Mesodermal Expression of Tbx1, a Gene Haploinsufficient in 22q11.2 Deletion Syndrome. Cereb Cortex. 2017 Mar 01;27(3):2210-2225
3J:196844 Furuta D, Yamane M, Tsujiuchi T, Moriyama R, Fukushima N, Lysophosphatidic acid induces neurite branch formation through LPA3. Mol Cell Neurosci. 2012 May;50(1):21-34
5*J:222260 Gladwyn-Ng IE, Li SS, Qu Z, Davis JM, Ngo L, Haas M, Singer J, Heng JI, Bacurd2 is a novel interacting partner to Rnd2 which controls radial migration within the developing mammalian cerebral cortex. Neural Dev. 2015;10:9
4J:139577 Heng JI, Nguyen L, Castro DS, Zimmer C, Wildner H, Armant O, Skowronska-Krawczyk D, Bedogni F, Matter JM, Hevner R, Guillemot F, Neurogenin 2 controls cortical neuron migration through regulation of Rnd2. Nature. 2008 Sep 4;455(7209):114-8
3J:231065 Heng JI, Qu Z, Ohtaka-Maruyama C, Okado H, Kasai M, Castro D, Guillemot F, Tan SS, The zinc finger transcription factor RP58 negatively regulates Rnd2 for the control of neuronal migration during cerebral cortical development. Cereb Cortex. 2015 Mar;25(3):806-16
2J:192488 McLoughlin HS, Fineberg SK, Ghosh LL, Tecedor L, Davidson BL, Dicer is required for proliferation, viability, migration and differentiation in corticoneurogenesis. Neuroscience. 2012 Oct 25;223:285-95
1J:205051 Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, Sestan N, Gage FH, Lein ES, Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
2J:174732 Pacary E, Heng J, Azzarelli R, Riou P, Castro D, Lebel-Potter M, Parras C, Bell DM, Ridley AJ, Parsons M, Guillemot F, Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron. 2011 Mar 24;69(6):1069-84
2J:190524 Shalom-Barak T, Zhang X, Chu T, Timothy Schaiff W, Reddy JK, Xu J, Sadovsky Y, Barak Y, Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55

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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory