Gene Expression Literature Summary

• Symbol: Gdf2
• Name: growth differentiation factor 2
• ID: MGI:1321394

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E7.5	E8.5	E9.5	E10	E10.5	E11	E11.5	E12.5	E13.5	E14	E14.5	E15	E15.5	E17.5	E18.5	P
Immunohistochemistry (section)																1
In situ RNA (section)						1		1	1	1				2		2	2
In situ reporter (knock in)					1												1
RT-PCR	1	1	2	1		1	1	1		1	1	2	1		2	1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gdf2  growth differentiation factor 2   (Synonyms: Bmp9)
Results	Reference
8	J:222016 Chen H, Brady Ridgway J, Sai T, Lai J, Warming S, Chen H, Roose-Girma M, Zhang G, Shou W, Yan M, Context-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11887-92
1	J:161416 Collette NM, Genetos DC, Murugesh D, Harland RM, Loots GG, Genetic evidence that SOST inhibits WNT signaling in the limb. Dev Biol. 2010 Jun 15;342(2):169-79
2	J:322702 Kaplan MM, Flucher BE, Counteractive and cooperative actions of muscle beta-catenin and CaV1.1 during early neuromuscular synapse formation. iScience. 2022 Apr 15;25(4):104025
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:184521 Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L, Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module. Dev Cell. 2012 May 15;22(5):913-26
1*	J:63418 Lopez-Coviella I, Berse B, Krauss R, Thies RS, Blusztajn JK, Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9. Science. 2000 Jul 14;289(5477):313-6
1	J:187360 McKean DM, Niswander L, Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly. Biol Open. 2012;1(9):874-883
1	J:100340 Mori T, Yuxing Z, Takaki H, Takeuchi M, Iseki K, Hagino S, Kitanaka J, Takemura M, Misawa H, Ikawa M, Okabe M, Wanaka A, The LIM homeobox gene, L3/Lhx8, is necessary for proper development of basal forebrain cholinergic neurons. Eur J Neurosci. 2004 Jun;19(12):3129-41
2*	J:108109 Oxburgh L, Chu GC, Michael SK, Robertson EJ, TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development. 2004 Sep;131(18):4593-605
1	J:164086 Suzuki Y, Ohga N, Morishita Y, Hida K, Miyazono K, Watabe T, BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo. J Cell Sci. 2010 May 15;123(Pt 10):1684-92
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
2	J:278336 Wang W, Chun H, Baek J, Sadik JE, Shirazyan A, Razavi P, Lopez N, Lyons KM, The TGFbeta type I receptor TGFbetaRI functions as an inhibitor of BMP signaling in cartilage. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15570-15579
1	J:185531 Wu H, Lu Y, Barik A, Joseph A, Taketo MM, Xiong WC, Mei L, beta-Catenin gain of function in muscles impairs neuromuscular junction formation. Development. 2012 Jul;139(13):2392-404
4*	J:270276 Yu L, Dawson LA, Yan M, Zimmel K, Lin YL, Dolan CP, Han M, Muneoka K, BMP9 stimulates joint regeneration at digit amputation wounds in mice. Nat Commun. 2019 Feb 5;10(1):424