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Gene Expression Literature Summary
Symbol
Name
ID
Tyrobp
TYRO protein tyrosine kinase binding protein
MGI:1277211

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E10.5 E13.5 E14 E14.5 E16 E17 E18 E P
Immunohistochemistry (section) 2 1 3
In situ RNA (section) 3 1
Northern blot 1 1 1 1
RT-PCR 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Tyrobp  TYRO protein tyrosine kinase binding protein   (Synonyms: DAP12, KARAP, killer cell activating receptor associated protein)
Results  Reference
1J:273194 Anderson SR, Zhang J, Steele MR, Romero CO, Kautzman AG, Schafer DP, Vetter ML, Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. J Neurosci. 2019 Mar 13;39(11):2025-2040
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*J:198109 Oeschger FM, Wang WZ, Lee S, Garcia-Moreno F, Goffinet AM, Arbones ML, Rakic S, Molnar Z, Gene expression analysis of the embryonic subplate. Cereb Cortex. 2012 Jun;22(6):1343-59
2J:96801 Roumier A, Bechade C, Poncer JC, Smalla KH, Tomasello E, Vivier E, Gundelfinger ED, Triller A, Bessis A, Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse. J Neurosci. 2004 Dec 15;24(50):11421-8
2J:137963 Roumier A, Pascual O, Bechade C, Wakselman S, Poncer JC, Real E, Triller A, Bessis A, Prenatal activation of microglia induces delayed impairment of glutamatergic synaptic function. PLoS One. 2008;3(7):e2595
1*J:149737 Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ, The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511
5*J:144613 Thrash JC, Torbett BE, Carson MJ, Developmental regulation of TREM2 and DAP12 expression in the murine CNS: implications for Nasu-Hakola disease. Neurochem Res. 2009 Jan;34(1):38-45
1J:140167 Wakselman S, Bechade C, Roumier A, Bernard D, Triller A, Bessis A, Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor. J Neurosci. 2008 Aug 6;28(32):8138-43
2J:100668 Xie X, He H, Colonna M, Seya T, Takai T, Croy BA, Pathways participating in activation of mouse uterine natural killer cells during pregnancy. Biol Reprod. 2005 Sep;73(3):510-8
1J:340740 Xu J, Zhou X, Zhang T, Zhang B, Xu PX, Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development. Front Cell Dev Biol. 2023;11:1233317

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory