Gene Expression Literature Summary

• Symbol: Myo15a
• Name: myosin XVA
• ID: MGI:1261811

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E11	E11.5	E12.5	E13.5	E14.5	E15	E15.5	E16.5	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)													1		1
In situ RNA (section)			1	1	1			8			2		2	1	6
Immunohistochemistry (whole mount)						1			1		1		2		4
Northern blot	1	1					1			1					3
RT-PCR					1					1		2			3
cDNA clones										1					2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Myo15a  myosin XVA   (Synonyms: Myo15)
Results	Reference
1	J:330604 Akturk A, Day M, Tarchini B, RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells. Sci Adv. 2022 Oct 21;8(42):eabq2826
7	J:63740 Anderson DW, Probst FJ, Belyantseva IA, Fridell RA, Beyer L, Martin DM, Wu D, Kachar B, Friedman TB, Raphael Y, Camper SA, The motor and tail regions of myosin XV are critical for normal structure and function of auditory and vestibular hair cells. Hum Mol Genet. 2000 Jul 22;9(12):1729-38
4	J:92621 Belyantseva IA, Boger ET, Friedman TB, Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundle. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13958-63
2	J:92326 Burton Q, Cole LK, Mulheisen M, Chang W, Wu DK, The role of Pax2 in mouse inner ear development. Dev Biol. 2004 Aug 1;272(1):161-75
1	J:104329 Choo D, Ward J, Reece A, Dou H, Lin Z, Greinwald J, Molecular mechanisms underlying inner ear patterning defects in kreisler mutants. Dev Biol. 2006 Jan 15;289(2):308-17
1*	J:244562 Giese APJ, Tang YQ, Sinha GP, Bowl MR, Goldring AC, Parker A, Freeman MJ, Brown SDM, Riazuddin S, Fettiplace R, Schafer WR, Frolenkov GI, Ahmed ZM, CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells. Nat Commun. 2017 Jun 29;8(1):43
1	J:157099 Grimsley-Myers CM, Sipe CW, Geleoc GS, Lu X, The small GTPase Rac1 regulates auditory hair cell morphogenesis. J Neurosci. 2009 Dec 16;29(50):15859-69
1	J:262601 Huang Y, Hill J, Yatteau A, Wong L, Jiang T, Petrovic J, Gan L, Dong L, Wu DK, Reciprocal Negative Regulation Between Lmx1a and Lmo4 Is Required for Inner Ear Formation. J Neurosci. 2018 Jun 6;38(23):5429-5440
2*	J:156945 Hwang CH, Guo D, Harris MA, Howard O, Mishina Y, Gan L, Harris SE, Wu DK, Role of bone morphogenetic proteins on cochlear hair cell formation: analyses of Noggin and Bmp2 mutant mice. Dev Dyn. 2010 Feb;239(2):505-13
1*	J:184419 Kawashima Y, Geleoc GS, Kurima K, Labay V, Lelli A, Asai Y, Makishima T, Wu DK, Della Santina CC, Holt JR, Griffith AJ, Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes. J Clin Invest. 2011 Dec;121(12):4796-809
3*	J:151359 Lelli A, Asai Y, Forge A, Holt JR, Geleoc GS, Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea. J Neurophysiol. 2009 Jun;101(6):2961-73
5*	J:58614 Liang Y, Wang A, Belyantseva IA, Anderson DW, Probst FJ, Barber TD, Miller W, Touchman JW, Jin L, Sullivan SL, Sellers JR, Camper SA, Lloyd RV, Kachar B, Friedman TB, Fridell RA, Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2. Genomics. 1999 Nov 1;61(3):243-58
1	J:98487 Lin Z, Cantos R, Patente M, Wu DK, Gbx2 is required for the morphogenesis of the mouse inner ear: a downstream candidate of hindbrain signaling. Development. 2005 May;132(10):2309-18
4*	J:48001 Probst FJ, Fridell RA, Raphael Y, Saunders TL, Wang A, Liang Y , Morell RJ , Touchman JW , Lyons RH , Noben-Trauth K , Friedman TB , Camper SA, Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene [see comments]. Science. 1998 May 29;280(5368):1444-7
1	J:79100 Riccomagno MM, Martinu L, Mulheisen M, Wu DK, Epstein DJ, Specification of the mammalian cochlea is dependent on Sonic hedgehog. Genes Dev. 2002 Sep 15;16(18):2365-78
1	J:195357 Roeseler DA, Sachdev S, Buckley DM, Joshi T, Wu DK, Xu D, Hannink M, Waters ST, Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2. PLoS One. 2012;7(11):e47366
1	J:189624 Son EJ, Wu L, Yoon H, Kim S, Choi JY, Bok J, Developmental gene expression profiling along the tonotopic axis of the mouse cochlea. PLoS One. 2012;7(7):e40735
4	J:271898 Tadenev ALD, Akturk A, Devanney N, Mathur PD, Clark AM, Yang J, Tarchini B, GPSM2-GNAI Specifies the Tallest Stereocilia and Defines Hair Bundle Row Identity. Curr Biol. 2019 Feb 19;
7*	J:49063 Wakabayashi Y, Takahashi Y, Kikkawa Y, Okano H, Mishima Y, Ushiki T , Yonekawa H , Kominami R, A novel type of myosin encoded by the mouse deafness gene shaker-2. Biochem Biophys Res Commun. 1998 Jul 30;248(3):655-9
2*	J:171573 Yoon H, Lee DJ, Kim MH, Bok J, Identification of genes concordantly expressed with Atoh1 during inner ear development. Anat Cell Biol. 2011 Mar;44(1):69-78