Gene Expression Literature Summary

• Symbol: Pik3ca
• Name: phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
• ID: MGI:1206581

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1.5	E2	E4	E7	E9.5	E10.5	E11.5	E12.5	E14.5	E15.5	E16.5	E17	E18.5	E	A
In situ protein (section)										1
In situ RNA (section)										2						1
In situ protein (whole mount)	1			1											1
In situ RNA (whole mount)						1					1
In situ reporter (knock in)							1
Northern blot					1								1		1	1
Western blot						1			1	1		1		1		4
RT-PCR		1	1			1		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pik3ca  phosphatidylinositol 3-kinase, catalytic, alpha polypeptide   (Synonyms: 6330412C24Rik, caPI3K, p110alpha)
Results	Reference
6*	J:54237 Bi L, Okabe I, Bernard DJ, Wynshaw-Boris A, Nussbaum RL, Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase. J Biol Chem. 1999 Apr 16;274(16):10963-8
2	J:129381 Eickholt BJ, Ahmed AI, Davies M, Papakonstanti EA, Pearce W, Starkey ML, Bilancio A, Need AC, Smith AJ, Hall SM, Hamers FP, Giese KP, Bradbury EJ, Vanhaesebroeck B, Control of Axonal Growth and Regeneration of Sensory Neurons by the p110delta PI 3-Kinase. PLoS ONE. 2007;2(9):e869
2	J:109024 Foukas LC, Claret M, Pearce W, Okkenhaug K, Meek S, Peskett E, Sancho S, Smith AJ, Withers DJ, Vanhaesebroeck B, Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation. Nature. 2006 May 18;441(7091):366-70
1*	J:171409 GUDMAP: the GenitoUrinary Development Molecular Anatomy Project, http://www.gudmap.org. 2004;
2	J:171508 Ikegami D, Akiyama H, Suzuki A, Nakamura T, Nakano T, Yoshikawa H, Tsumaki N, Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways. Development. 2011 Apr;138(8):1507-19
1	J:141066 Park KK, Liu K, Hu Y, Smith PD, Wang C, Cai B, Xu B, Connolly L, Kramvis I, Sahin M, He Z, Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway. Science. 2008 Nov 7;322(5903):963-6
3	J:100565 Riley JK, Carayannopoulos MO, Wyman AH, Chi M, Ratajczak CK, Moley KH, The PI3K/Akt pathway is present and functional in the preimplantation mouse embryo. Dev Biol. 2005 Aug 15;284(2):377-86
1	J:164696 Tan Y, You H, Coffey FJ, Wiest DL, Testa JR, Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development. Genesis. 2010 Sep;48(9):531-9
2*	J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:133488 Wolf AM, Lyuksyutova AI, Fenstermaker AG, Shafer B, Lo CG, Zou Y, Phosphatidylinositol-3-kinase-atypical protein kinase C signaling is required for Wnt attraction and anterior-posterior axon guidance. J Neurosci. 2008 Mar 26;28(13):3456-67
5	J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54