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Gene Expression Literature Summary
Symbol
Name
ID
Gfra3
glial cell line derived neurotrophic factor family receptor alpha 3
MGI:1201403

24 matching records from 24 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1.5 E2.5 E3.5 E7 E9.5 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E18 E18.5 E19 E20 E P
Immunohistochemistry (section) 1 1 1 1
In situ RNA (section) 1 1 3 1 3 2 4 2 4 2 2 2 1 3 2 1 1 2 14
In situ RNA (whole mount) 1 1 1 2
In situ reporter (knock in) 1 1 1
Northern blot 1 1 1 1 1 1 1 1 1 2
RT-PCR 1 1 1 1 1 1 1 2
cDNA clones 1 1 2
RNase protection 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Gfra3  glial cell line derived neurotrophic factor family receptor alpha 3   (Synonyms: GFRalpha3, GFR alpha-3)
Results  Reference
2J:47662 Baloh RH, Gorodinsky A, Golden JP, Tansey MG, Keck CL, Popescu NC, Johnson EM Jr, Milbrandt J, GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family. Proc Natl Acad Sci U S A. 1998 May 12;95(10):5801-6
3J:64589 Baudet C, Mikaels A, Westphal H, Johansen J, Johansen TE, Ernfors P, Positive and negative interactions of GDNF, NTN and ART in developing sensory neuron subpopulations, and their collaboration with neurotrophins. Development. 2000 Oct;127(20):4335-44
5J:90843 Bolon B, Jing S, Asuncion F, Scully S, Pisegna M, Van GY, Hu Z, Yu YB, Min H, Wild K, Rosenfeld RD, Tarpley J, Carnahan J, Duryea D, Hill D, Kaufman S, Yan XQ, Juan T, Christensen K, McCabe J, Simonet WS, The candidate neuroprotective agent artemin induces autonomic neural dysplasia without preventing peripheral nerve dysfunction. Toxicol Pathol. 2004 May-Jun;32(3):275-94
4J:54911 Fundin BT, Mikaels A, Westphal H, Ernfors P, A rapid and dynamic regulation of GDNF-family ligands and receptors correlate with the developmental dependency of cutaneous sensory innervation. Development. 1999 Jun;126(12):2597-610
1J:238230 Furlan A, La Manno G, Lubke M, Haring M, Abdo H, Hochgerner H, Kupari J, Usoskin D, Airaksinen MS, Oliver G, Linnarsson S, Ernfors P, Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control. Nat Neurosci. 2016 Oct;19(10):1331-40
2J:210892 Gorokhova S, Gaillard S, Urien L, Malapert P, Legha W, Baronian G, Desvignes JP, Alonso S, Moqrich A, Uncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptor. PLoS Genet. 2014 Feb;10(2):e1004081
3*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1J:78008 Honma Y, Araki T, Gianino S, Bruce A, Heuckeroth R, Johnson E, Milbrandt J, Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons. Neuron. 2002 Jul 18;35(2):267-82
1J:266563 Jorgensen MC, de Lichtenberg KH, Collin CA, Klinck R, Ekberg JH, Engelstoft MS, Lickert H, Serup P, Neurog3-dependent pancreas dysgenesis causes ectopic pancreas in Hes1 mutant mice. Development. 2018 Sep 3;145(17)
4*J:152095 Li J, Klein C, Liang C, Rauch R, Kawamura K, Hsueh AJ, Autocrine regulation of early embryonic development by the artemin-GFRA3 (GDNF family receptor-alpha 3) signaling system in mice. FEBS Lett. 2009 Aug 6;583(15):2479-85
2*J:63721 Lindahl M, Timmusk T, Rossi J, Saarma M, Airaksinen MS, Expression and alternative splicing of mouse Gfra4 suggest roles in endocrine cell development. Mol Cell Neurosci. 2000 Jun;15(6):522-33
1J:108404 Lindfors PH, Lindahl M, Rossi J, Saarma M, Airaksinen MS, Ablation of persephin receptor glial cell line-derived neurotrophic factor family receptor alpha4 impairs thyroid calcitonin production in young mice. Endocrinology. 2006 May;147(5):2237-44
1J:157722 Luo W, Enomoto H, Rice FL, Milbrandt J, Ginty DD, Molecular identification of rapidly adapting mechanoreceptors and their developmental dependence on ret signaling. Neuron. 2009 Dec 24;64(6):841-56
4J:126484 Luo W, Wickramasinghe SR, Savitt JM, Griffin JW, Dawson TM, Ginty DD, A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. Neuron. 2007 Jun 7;54(5):739-54
8J:50254 Luukko K, Saarma M, Thesleff I, Neurturin mRNA expression suggests roles in trigeminal innervation of the first branchial arch and in tooth formation. Dev Dyn. 1998 Oct;213(2):207-19
5J:63340 Mikaels A, Livet J, Westphal H, De Lapeyriere O, Ernfors P, A dynamic regulation of GDNF-family receptors correlates with a specific trophic dependency of cranial motor neuron subpopulations during development. Eur J Neurosci. 2000 Feb;12(2):446-56
8J:45661 Naveilhan P, Baudet C, Mikaels A, Shen L, Westphal H, Ernfors P, Expression and regulation of GFRalpha3, a glial cell line-derived neurotrophic factor family receptor. Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1295-300
7J:57342 Nishino J, Mochida K, Ohfuji Y, Shimazaki T, Meno C, Ohishi S, Matsuda Y, Fujii H, Saijoh Y, Hamada H, GFR alpha3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion. Neuron. 1999 Aug;23(4):725-36
7J:46797 Nomoto S, Ito S, Yang LX, Kiuchi K, Molecular cloning and expression analysis of GFR alpha-3, a novel cDNA related to GDNFR alpha and NTNR alpha. Biochem Biophys Res Commun. 1998 Mar 27;244(3):849-53
4*J:260642 Patel A, Harker N, Moreira-Santos L, Ferreira M, Alden K, Timmis J, Foster K, Garefalaki A, Pachnis P, Andrews P, Enomoto H, Milbrandt J, Pachnis V, Coles MC, Kioussis D, Veiga-Fernandes H, Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems. Sci Signal. 2012 Jul 31;5(235):ra55
1J:89887 Rossi J, Tomac A, Saarma M, Airaksinen MS, Distinct roles for GFRalpha1 and GFRalpha2 signalling in different cranial parasympathetic ganglia in vivo. Eur J Neurosci. 2000 Nov;12(11):3944-52
5*J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
5J:47085 Widenfalk J, Tomac A, Lindqvist E, Hoffer B, Olson L, GFRalpha-3, a protein related to GFRalpha-1, is expressed in developing peripheral neurons and ensheathing cells. Eur J Neurosci. 1998 Apr;10(4):1508-17
7*J:45720 Worby CA, Vega QC, Chao HH, Seasholtz AF, Thompson RC, Dixon JE, Identification and characterization of GFRalpha-3, a novel Co-receptor belonging to the glial cell line-derived neurotrophic receptor family. J Biol Chem. 1998 Feb 6;273(6):3502-8

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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory