Gene Expression Literature Summary

• Symbol: Mid1
• Name: midline 1
• ID: MGI:1100537

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E9.5	E10.5	E11	E11.5	E12	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E18	E18.5	P
Immunohistochemistry (section)			1
In situ RNA (section)			1		1		2	4		5	1			2		1	1	2
In situ RNA (whole mount)		1	3		1							1
Northern blot	1			1	1						1				1			1
Western blot			1			1					1					1		2
RT-PCR		2	2		2		2	1	1	1			1			1	1	4
cDNA clones					2													4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mid1  midline 1   (Synonyms: 61B3-R, DXHXS1141, Fxy, Trim18)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:341393 Cheffer A, Garcia-Miralles M, Maier E, Akol I, Franz H, Srinivasan VSV, Vogel T, DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons. Cereb Cortex. 2023 Sep 26;33(19):10272-10285
5*	J:46361 Dal Zotto L, Quaderi NA, Elliott R, Lingerfelter PA, Carrel L , Valsecchi V , Montini E , Yen CH , Chapman V , Kalcheva I , Arrigo G , Zuffardi O , Thomas S , Willard HF , Ballabio A , Disteche CM , Rugarli EI, The mouse Mid1 gene: implications for the pathogenesis of Opitz syndrome and the evolution of the mammalian pseudoautosomal region. Hum Mol Genet. 1998 Mar;7(3):489-99
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:152838 Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD, A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J Neurosci. 2009 Sep 9;29(36):11399-408
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
6	J:157828 Lancioni A, Pizzo M, Fontanella B, Ferrentino R, Napolitano LM, De Leonibus E, Meroni G, Lack of Mid1, the mouse ortholog of the Opitz syndrome gene, causes abnormal development of the anterior cerebellar vermis. J Neurosci. 2010 Feb 24;30(8):2880-7
6*	J:244447 Li B, Zhou T, Zou Y, Mid1/Mid2 expression in craniofacial development and a literature review of X-linked opitz syndrome. Mol Genet Genomic Med. 2016 Jan;4(1):95-105
3	J:333209 Liang Y, Song C, Li J, Li T, Zhang C, Zou Y, Morphometric analysis of the size-adjusted linear dimensions of the skull landmarks revealed craniofacial dysmorphology in Mid1-cKO mice. BMC Genomics. 2023 Feb 9;24(1):68
12*	J:202973 Lu T, Chen R, Cox TC, Moldrich RX, Kurniawan N, Tan G, Perry JK, Ashworth A, Bartlett PF, Xu L, Zhang J, Lu B, Wu M, Shen Q, Liu Y, Richards LJ, Xiong Z, X-linked microtubule-associated protein, Mid1, regulates axon development. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19131-6
3*	J:43704 Palmer S, Perry J, Kipling D, Ashworth A, A gene spans the pseudoautosomal boundary in mice. Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):12030-5
2*	J:43842 Quaderi NA, Schweiger S, Gaudenz K, Franco B, Rugarli EI, Berger W, Feldman GJ, Volta M, Andolfi G, Gilgenkrantz S, Marion RW, Hennekam RC, Opitz JM, Muenke M, Ropers HH, Ballabio A, Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22. Nat Genet. 1997 Nov;17(3):285-91
1	J:226305 Romand R, Ripp R, Poidevin L, Boeglin M, Geffers L, Dolle P, Poch O, Integrated annotation and analysis of in situ hybridization images using the ImAnno system: application to the ear and sensory organs of the fetal mouse. PLoS One. 2015;10(2):e0118024
1*	J:202837 Rowton M, Ramos P, Anderson DM, Rhee JM, Cunliffe HE, Rawls A, Regulation of mesenchymal-to-epithelial transition by PARAXIS during somitogenesis. Dev Dyn. 2013 Nov;242(11):1332-44
2*	J:152946 Sferruzzi-Perri AN, Macpherson AM, Roberts CT, Robertson SA, Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice. Biol Reprod. 2009 Jul;81(1):207-21
4*	J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26
5*	J:49564 Van den Veyver IB, Cormier TA, Jurecic V, Baldini A, Zoghbi HY, Characterization and physical mapping in human and mouse of a novel RING finger gene in Xp22. Genomics. 1998 Jul 15;51(2):251-61
2	J:206774 Wolstenholme JT, Rissman EF, Bekiranov S, Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes. Genes Brain Behav. 2013 Mar;12(2):166-80
3*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48