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Gene Expression Literature Summary
Symbol
Name
ID
Nsdhl
NAD(P) dependent steroid dehydrogenase-like
MGI:1099438

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E6.5 E7.5 E8.5 E9.5 E10.5 E11.5 E12.5 E13.5 E14.5 E15.5 E16.5 E17.5 E18.5 E P
Immunohistochemistry (section) 1 1 1 3 1 2 1 1 1 4
In situ RNA (section) 1 2 1 1
Northern blot 1 1 1 1 1 1 1 1 1 1 1
Western blot 1 1 2
RT-PCR 1 2
cDNA clones 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Nsdhl  NAD(P) dependent steroid dehydrogenase-like   (Synonyms: bare patches, Bpa, H105E3, Str, striated, XAP104)
Results  Reference
2J:95508 Caldas H, Cunningham D, Wang X, Jiang F, Humphries L, Kelley RI, Herman GE, Placental defects are associated with male lethality in bare patches and striated embryos deficient in the NAD(P)H Steroid Dehydrogenase-like (NSDHL) Enzyme. Mol Genet Metab. 2005 Jan;84(1):48-60
3J:220990 Cunningham D, DeBarber AE, Bir N, Binkley L, Merkens LS, Steiner RD, Herman GE, Analysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS development. Hum Mol Genet. 2015 May 15;24(10):2808-25
11*J:155028 Cunningham D, Spychala K, McLarren KW, Garza LA, Boerkoel CF, Herman GE, Developmental expression pattern of the cholesterogenic enzyme NSDHL and negative selection of NSDHL-deficient cells in the heterozygous Bpa(1H)/+ mouse. Mol Genet Metab. 2009 Dec;98(4):356-66
3J:155338 Cunningham D, Talabere T, Bir N, Kennedy M, McBride KL, Herman GE, Significant contributions of the extraembryonic membranes and maternal genotype to the placental pathology in heterozygous Nsdhl deficient female embryos. Hum Mol Genet. 2010 Jan 15;19(2):364-73
1J:99308 Davies W, Isles A, Smith R, Karunadasa D, Burrmann D, Humby T, Ojarikre O, Biggin C, Skuse D, Burgoyne P, Wilkinson L, Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice. Nat Genet. 2005 Jun;37(6):625-9
1*J:33576 Levin ML, Chatterjee A, Pragliola A, Worley KC, Wehnert M, Zhuchenko O, Smith RF, Lee CC, Herman GE, A comparative transcription map of the murine bare patches (Bpa) and striated (Str) critical regions and human Xq28. Genome Res. 1996 Jun;6(6):465-77
15*J:55488 Liu XY, Dangel AW, Kelley RI, Zhao W, Denny P, Botcherby M, Cattanach B , Peters J , Hunsicker PR , Mallon AM , Strivens MA , Bate R , Miller W , Rhodes M , Brown SD , Herman GE, The gene mutated in bare patches and striated mice encodes a novel 3beta-hydroxysteroid dehydrogenase. Nat Genet. 1999 Jun;22(2):182-7
4*J:170232 McLarren KW, Severson TM, du Souich C, Stockton DW, Kratz LE, Cunningham D, Hendson G, Morin RD, Wu D, Paul JE, An J, Nelson TN, Chou A, DeBarber AE, Merkens LS, Michaud JL, Waters PJ, Yin J, McGillivray B, Demos M, Rouleau GA, Grzeschik KH, Smith R, Tarpey PS, Shears D, Schwartz CE, Gecz J, Stratton MR, Arbour L, Hurlburt J, Van Allen MI, Herman GE, Zhao Y, Moore R, Kelley RI, Jones SJ, Steiner RD, Raymond FL, Marra MA, Boerkoel CF, Hypomorphic temperature-sensitive alleles of NSDHL cause CK syndrome. Am J Hum Genet. 2010 Dec 10;87(6):905-14
1J:224387 Sisecioglu M, Budak H, Geffers L, Cankaya M, Ciftci M, Thaller C, Eichele G, Kufrevioglu OI, Ozdemir H, A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo. J Lipid Res. 2015 Aug;56(8):1551-9
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory