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Gene Expression Literature Summary
Symbol
Name
ID
Cfc1
cripto, FRL-1, cryptic family 1
MGI:109448

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1.5 E2 E4 E4.5 E5 E5.5 E6 E6.5 E7 E7.5 E8 E8.5 E9.5 E10.5 E11.5 E13.5 E A
In situ RNA (section) 1 1 1 1 1 1
In situ RNA (whole mount) 1 1 1 1 2 1 2 4 9 2
In situ reporter (knock in) 1 1
RT-PCR 1 1 1 1
RNase protection 1 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cfc1  cripto, FRL-1, cryptic family 1   (Synonyms: b2b970Clo, cryptic)
Results  Reference
1*J:92872 Bamforth SD, Braganca J, Farthing CR, Schneider JE, Broadbent C, Michell AC, Clarke K, Neubauer S, Norris D, Brown NA, Anderson RH, Bhattacharya S, Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway. Nat Genet. 2004 Dec;36(11):1189-96
8J:160475 Chu J, Shen MM, Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis. Dev Biol. 2010 Jun 1;342(1):63-73
2*J:79391 Fujiwara T, Dehart DB, Sulik KK, Hogan BL, Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse. Development. 2002 Oct;129(20):4685-96
2J:58530 Gaio U, Schweickert A, Fischer A, Garratt AN, Muller T, Ozcelik C, Lankes W, Strehle M, Britsch S, Blum M, Birchmeier C, A role of the cryptic gene in the correct establishment of the left-right axis. Curr Biol. 1999 Nov 18;9(22):1339-42
2*J:142123 Ishimura A, Chida S, Osada S, Man1, an inner nuclear membrane protein, regulates left-right axis formation by controlling nodal signaling in a node-independent manner. Dev Dyn. 2008 Dec;237(12):3565-76
1J:132584 Liguori GL, Borges AC, D'Andrea D, Liguoro A, Goncalves L, Salgueiro AM, Persico MG, Belo JA, Cripto-independent Nodal signaling promotes positioning of the A-P axis in the early mouse embryo. Dev Biol. 2008 Mar 15;315(2):280-9
1J:137629 Mine N, Anderson RM, Klingensmith J, BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment. Development. 2008 Jul;135(14):2425-34
1J:104377 Nakaya MA, Biris K, Tsukiyama T, Jaime S, Rawls JA, Yamaguchi TP, Wnt3alinks left-right determination with segmentation and anteroposterior axis elongation. Development. 2005 Dec;132(24):5425-36
2J:154471 Natale DR, Hemberger M, Hughes M, Cross JC, Activin promotes differentiation of cultured mouse trophoblast stem cells towards a labyrinth cell fate. Dev Biol. 2009 Nov 1;335(1):120-31
1J:198687 Nowotschin S, Costello I, Piliszek A, Kwon GS, Mao CA, Klein WH, Robertson EJ, Hadjantonakis AK, The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo. Genes Dev. 2013 May 1;27(9):997-1002
2J:126337 Oki S, Hashimoto R, Okui Y, Shen MM, Mekada E, Otani H, Saijoh Y, Hamada H, Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo. Development. 2007 Nov;134(21):3893-904
1J:82703 Saijoh Y, Oki S, Ohishi S, Hamada H, Left-right patterning of the mouse lateral plate requires nodal produced in the node. Dev Biol. 2003 Apr 1;256(1):160-72
1J:185535 Saund RS, Kanai-Azuma M, Kanai Y, Kim I, Lucero MT, Saijoh Y, Gut endoderm is involved in the transfer of left-right asymmetry from the node to the lateral plate mesoderm in the mouse embryo. Development. 2012 Jul;139(13):2426-35
2J:74138 Shen MM, Identification of differentially expressed genes in mouse development using differential display and in situ hybridization. Methods. 2001 May;24(1):15-27
10*J:38387 Shen MM, Wang H, Leder P, A differential display strategy identifies Cryptic, a novel EGF-related gene expressed in the axial and lateral mesoderm during mouse gastrulation. Development. 1997 Jan;124(2):429-42
1J:189072 Spiller CM, Feng CW, Jackson A, Gillis AJ, Rolland AD, Looijenga LH, Koopman P, Bowles J, Endogenous Nodal signaling regulates germ cell potency during mammalian testis development. Development. 2012 Nov;139(22):4123-32
2*J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
1J:175111 Zhang XM, Ramalho-Santos M, McMahon AP, Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node. Cell. 2001 Jul 27;106(2):781-92

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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory