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Gene Expression Literature Summary
Symbol
Name
ID
Cbx5
chromobox 5
MGI:109372

17 matching records from 17 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E2 E2.5 E3 E3.5 E4 E7.5 E8.5 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13.5 E14.5 E15.5 E16.5 E17.5 E18 E18.5 E P
Immunohistochemistry (section) 1 1 1 1 1 1 1 4
In situ RNA (section) 1 1 1 1
Immunohistochemistry (whole mount) 1 1 1 1 1 1 1 1 1 1
In situ reporter (knock in) 1 1
Western blot 1 1 2 1 1 1 1 3
RT-PCR 1 1 1 1 1 1 1 1 4
cDNA clones 1 1 1 1 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cbx5  chromobox 5   (Synonyms: 2610029O15Rik, heterochromatin protein 1 alpha, HP1, Hp1a, HP1a, Hp1alpha)
Results  Reference
1J:182789 Abe K, Naruse C, Kato T, Nishiuchi T, Saitou M, Asano M, Loss of heterochromatin protein 1 gamma reduces the number of primordial germ cells via impaired cell cycle progression in mice. Biol Reprod. 2011 Nov;85(5):1013-24
2J:186901 Brown JP, Bullwinkel J, Baron-Luhr B, Billur M, Schneider P, Winking H, Singh PB, HP1gamma function is required for male germ cell survival and spermatogenesis. Epigenetics Chromatin. 2010;3(1):9
2J:170392 Herzog M, Wendling O, Guillou F, Chambon P, Mark M, Losson R, Cammas F, TIF1beta association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesis. Dev Biol. 2011 Feb 15;350(2):548-58
1*J:121991 Katayama K, Furuno A, Akiyama K, Tsuji T, Kunieda T, Characterization of chromosomal inversion of the mouse hairy ears (Eh) mutation associated with cleft palate. Mamm Genome. 2007 Apr;18(4):246-54
1J:236026 Kinsella E, Dora N, Mellis D, Lettice L, Deveney P, Hill R, Ditzel M, Use of a Conditional Ubr5 Mutant Allele to Investigate the Role of an N-End Rule Ubiquitin-Protein Ligase in Hedgehog Signalling and Embryonic Limb Development. PLoS One. 2016;11(6):e0157079
8J:37212 Le Douarin B, Nielsen AL, Garnier JM, Ichinose H, Jeanmougin F, Losson R, Chambon P, A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. EMBO J. 1996 Dec 2;15(23):6701-15
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
11*J:315732 Meglicki M, Teperek-Tkacz M, Borsuk E, Appearance and heterochromatin localization of HP1alpha in early mouse embryos depends on cytoplasmic clock and H3S10 phosphorylation. Cell Cycle. 2012 Jun 1;11(11):2189-205
3J:304076 Naruse C, Abe K, Yoshihara T, Kato T, Nishiuchi T, Asano M, Heterochromatin protein 1gamma deficiency decreases histone H3K27 methylation in mouse neurosphere neuronal genes. FASEB J. 2020 Mar;34(3):3956-3968
1J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167
7*J:55698 Remboutsika E, Lutz Y, Gansmuller A, Vonesch JL, Losson R, Chambon P, The putative nuclear receptor mediator TIF1alpha is tightly associated with euchromatin. J Cell Sci. 1999 Jun;112(Pt 11):1671-83
4*J:185981 Thliveris AT, Clipson L, Sommer LL, Schoenike BA, Hasenstein JR, Schlamp CL, Alexander CM, Newton MA, Dove WF, Amos-Landgraf JM, Regulated Expression of Chromobox Homolog 5 Revealed in Tumors of Apc(Min) (/+) ROSA11 Gene Trap Mice. G3 (Bethesda). 2012 May;2(5):569-78
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1*J:187480 Westendorp B, Major JL, Nader M, Salih M, Leenen FH, Tuana BS, The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy. FASEB J. 2012 Jun;26(6):2569-79
10J:183069 Wongtawan T, Taylor JE, Lawson KA, Wilmut I, Pennings S, Histone H4K20me3 and HP1alpha are late heterochromatin markers in development, but present in undifferentiated embryonic stem cells. J Cell Sci. 2011 Jun 1;124(Pt 11):1878-90
1*J:264140 Zhang D, Xie D, Lin X, Ma L, Chen J, Zhang D, Wang Y, Duo S, Feng Y, Zheng C, Jiang B, Ning Y, Han C, The transcription factor SOX30 is a key regulator of mouse spermiogenesis. Development. 2018 May 30;145(11):dev164723
1J:244911 Zhang M, Chen D, Xia J, Han W, Cui X, Neuenkirchen N, Hermes G, Sestan N, Lin H, Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins. Genes Dev. 2017 Jul 1;31(13):1354-1369

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory