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Gene Expression Literature Summary
actinin alpha 2

48 matching records from 48 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7 E8 E8.5 E9.5 E10 E10.5 E11 E11.5 E12.5 E13.5 E14 E14.5 E15 E15.5 E16.5 E17 E17.5 E18.5 E P
Immunohistochemistry (section) 3 2 5 1 3 5 6 2 4 3 4 5 2 16
In situ RNA (section) 2
Immunohistochemistry (whole mount) 1 1 1 1 1 1 1
Northern blot 1
Western blot 1 1 1 2 1 5
RT-PCR 1 1 1 1 4 2 2 1 2 1 1 1 1 3
cDNA clones 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Actn2  actinin alpha 2   (Synonyms: 1110008F24Rik)
Results  Reference
3J:237129 Boogerd CJ, Aneas I, Sakabe N, Dirschinger RJ, Cheng QJ, Zhou B, Chen J, Nobrega MA, Evans SM, Probing chromatin landscape reveals roles of endocardial TBX20 in septation. J Clin Invest. 2016 Aug 01;126(8):3023-35
1J:57924 Brancaccio M, uazzone S, Menini N, Sibona E, Hirsch E, De Andrea M, Rocchi M, Altruda F, Tarone G, Silengo L, Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain. J Biol Chem. 1999 Oct 8;274(41):29282-8
3J:195548 Brody MJ, Hacker TA, Patel JR, Feng L, Sadoshima J, Tevosian SG, Balijepalli RC, Moss RL, Lee Y, Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy. PLoS One. 2012;7(12):e51621
1J:199157 Caruso N, Herberth B, Bartoli M, Puppo F, Dumonceaux J, Zimmermann A, Denadai S, Lebosse M, Roche S, Geng L, Magdinier F, Attarian S, Bernard R, Maina F, Levy N, Helmbacher F, Deregulation of the Protocadherin Gene FAT1 Alters Muscle Shapes: Implications for the Pathogenesis of Facioscapulohumeral Dystrophy. PLoS Genet. 2013 Jun;9(6):e1003550
3J:236425 Clay H, Wilsbacher LD, Wilson SJ, Duong DN, McDonald M, Lam I, Park KE, Chun J, Coughlin SR, Sphingosine 1-phosphate receptor-1 in cardiomyocytes is required for normal cardiac development. Dev Biol. 2016 Oct 1;418(1):157-65
1*J:127524 Davie JK, Cho JH, Meadows E, Flynn JM, Knapp JR, Klein WH, Target gene selectivity of the myogenic basic helix-loop-helix transcription factor myogenin in embryonic muscle. Dev Biol. 2007 Nov 15;311(2):650-64
1J:108510 Diehl AG, Zareparsi S, Qian M, Khanna R, Angeles R, Gage PJ, Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose. Invest Ophthalmol Vis Sci. 2006 May;47(5):1785-93
1*J:99495 Dominguez JN, Navarro F, Franco D, Thompson RP, Aranega AE, Temporal and spatial expression pattern of beta1 sodium channel subunit during heart development. Cardiovasc Res. 2005 Mar 1;65(4):842-50
1*J:110295 Durham JT, Brand OM, Arnold M, Reynolds JG, Muthukumar L, Weiler H, Richardson JA, Naya FJ, Myospryn is a direct transcriptional target for MEF2A that encodes a striated muscle, alpha-actinin-interacting, costamere-localized protein. J Biol Chem. 2006 Mar 10;281(10):6841-9
2J:158797 Gokhin DS, Lewis RA, McKeown CR, Nowak RB, Kim NE, Littlefield RS, Lieber RL, Fowler VM, Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology. J Cell Biol. 2010 Apr 5;189(1):95-109
1J:191565 Grote P, Wittler L, Hendrix D, Koch F, Wahrisch S, Beisaw A, Macura K, Blass G, Kellis M, Werber M, Herrmann BG, The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse. Dev Cell. 2013 Jan 28;24(2):206-14
1J:172023 Guo C, Sun Y, Zhou B, Adam RM, Li X, Pu WT, Morrow BE, Moon A, Li X, A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis. J Clin Invest. 2011 Apr 1;121(4):1585-95
1J:223458 He L, Tian X, Zhang H, Hu T, Huang X, Zhang L, Wang Z, Zhou B, BAF200 is required for heart morphogenesis and coronary artery development. PLoS One. 2014;9(10):e109493
11J:104324 Hirschy A, Schatzmann F, Ehler E, Perriard JC, Establishment of cardiac cytoarchitecture in the developing mouse heart. Dev Biol. 2006 Jan 15;289(2):430-41
1*J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
6*J:91335 Huang SM, Huang CJ, Wang WM, Kang JC, Hsu WC, The enhancement of nuclear receptor transcriptional activation by a mouse actin-binding protein, alpha actinin 2. J Mol Endocrinol. 2004 Apr;32(2):481-96
2J:212665 Huang ZP, Young Seok H, Zhou B, Chen J, Chen JF, Tao Y, Pu WT, Wang DZ, CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circ Res. 2012 Mar 16;110(6):818-30
1J:146619 Ieda M , Tsuchihashi T , Ivey KN , Ross RS , Hong TT , Shaw RM , Srivastava D, Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell. 2009 Feb;16(2):233-44
2J:224310 Ishihara T, Ban-Ishihara R, Maeda M, Matsunaga Y, Ichimura A, Kyogoku S, Aoki H, Katada S, Nakada K, Nomura M, Mizushima N, Mihara K, Ishihara N, Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development. Mol Cell Biol. 2015 Jan;35(1):211-23
2*J:188473 Kan-o M, Takeya R, Taniguchi K, Tanoue Y, Tominaga R, Sumimoto H, Expression and subcellular localization of mammalian formin Fhod3 in the embryonic and adult heart. PLoS One. 2012;7(4):e34765
1J:103761 Kaneko-Oshikawa C, Nakagawa T, Yamada M, Yoshikawa H, Matsumoto M, Yada M, Hatakeyama S, Nakayama K, Nakayama KI, Mammalian E4 is required for cardiac development and maintenance of the nervous system. Mol Cell Biol. 2005 Dec;25(24):10953-64
1J:83911 Kos CH, Le TC, Sinha S, Henderson JM, Kim SH, Sugimoto H, Kalluri R, Gerszten RE, Pollak MR, Mice deficient in alpha-actinin-4 have severe glomerular disease. J Clin Invest. 2003 Jun;111(11):1683-90
8J:155281 Krishnan J, Ahuja P, Bodenmann S, Knapik D, Perriard E, Krek W, Perriard JC, Essential role of developmentally activated hypoxia-inducible factor 1alpha for cardiac morphogenesis and function. Circ Res. 2008 Nov 7;103(10):1139-46
1J:212637 Lescroart F, Mohun T, Meilhac SM, Bennett M, Buckingham M, Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing. Circ Res. 2012 Oct 26;111(10):1313-22
7J:97478 Lu S, Borst DE, Horowits R, N-RAP expression during mouse heart development. Dev Dyn. 2005 May;233(1):201-12
3J:226036 Maddala R, Nagendran T, Lang RA, Morozov A, Rao PV, Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. Dev Biol. 2015 Oct 1;406(1):74-91
2J:235199 Mastrototaro G, Liang X, Li X, Carullo P, Piroddi N, Tesi C, Gu Y, Dalton ND, Peterson KL, Poggesi C, Sheikh F, Chen J, Bang ML, Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers. Cardiovasc Res. 2015 Jul 15;107(2):216-25
1J:211921 McKeown CR, Nowak RB, Gokhin DS, Fowler VM, Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo. Dev Dyn. 2014 Jun;243(6):800-17
7J:70373 Mills M, Yang N, Weinberger R, Vander Woude DL, Beggs AH, Easteal S, North K, Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy. Hum Mol Genet. 2001 Jun 15;10(13):1335-46
1J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97
2J:172560 Nagy II, Railo A, Rapila R, Hast T, Sormunen R, Tavi P, Rasanen J, Vainio SJ, Wnt-11 signalling controls ventricular myocardium development by patterning N-cadherin and beta-catenin expression. Cardiovasc Res. 2010 Jan 1;85(1):100-9
1J:168140 Nguyen AT, Xiao B, Neppl RL, Kallin EM, Li J, Chen T, Wang DZ, Xiao X, Zhang Y, DOT1L regulates dystrophin expression and is critical for cardiac function. Genes Dev. 2011 Feb 1;25(3):263-74
3J:69803 Palmer S, Groves N, Schindeler A, Yeoh T, Biben C, Wang CC, Sparrow DB, Barnett L, Jenkins NA, Copeland NG, Koentgen F, Mohun T, Harvey RP, The small muscle-specific protein Csl modifies cell shape and promotes myocyte fusion in an insulin-like growth factor 1-dependent manner. J Cell Biol. 2001 May 28;153(5):985-98
1*J:29279 Patapoutian A, Yoon JK, Miner JH, Wang S, Stark K, Wold B, Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome. Development. 1995 Oct;121(10):3347-58
1J:76364 Pun S, Sigrist M, Santos AF, Ruegg MA, Sanes JR, Jessell TM, Arber S, Caroni P, An intrinsic distinction in neuromuscular junction assembly and maintenance in different skeletal muscles. Neuron. 2002 Apr 25;34(3):357-70
2J:178379 Richard AF, Demignon J, Sakakibara I, Pujol J, Favier M, Strochlic L, Le Grand F, Sgarioto N, Guernec A, Schmitt A, Cagnard N, Huang R, Legay C, Guillet-Deniau I, Maire P, Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev Biol. 2011 Nov 15;359(2):303-20
1J:144217 Risebro CA, Searles RG, Melville AA, Ehler E, Jina N, Shah S, Pallas J, Hubank M, Dillard M, Harvey NL, Schwartz RJ, Chien KR, Oliver G, Riley PR, Prox1 maintains muscle structure and growth in the developing heart. Development. 2009 Feb;136(3):495-505
2J:171727 Schlesinger J, Schueler M, Grunert M, Fischer JJ, Zhang Q, Krueger T, Lange M, Tonjes M, Dunkel I, Sperling SR, The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs. PLoS Genet. 2011 Feb;7(2):e1001313
4J:158984 Shimoji K, Yuasa S, Onizuka T, Hattori F, Tanaka T, Hara M, Ohno Y, Chen H, Egasgira T, Seki T, Yae K, Koshimizu U, Ogawa S, Fukuda K, G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs. Cell Stem Cell. 2010 Mar 5;6(3):227-37
1J:229358 Teo ZL, McQueen-Miscamble L, Turner K, Martinez G, Madakashira B, Dedhar S, Robinson ML, de Iongh RU, Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation. Exp Eye Res. 2014 Apr;121:130-42
2J:233994 Tian Y, Liu Y, Wang T, Zhou N, Kong J, Chen L, Snitow M, Morley M, Li D, Petrenko N, Zhou S, Lu M, Gao E, Koch WJ, Stewart KM, Morrisey EE, A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice. Sci Transl Med. 2015 Mar 18;7(279):279ra38
1J:175037 Urbanek K, Cabral-da-Silva MC, Ide-Iwata N, Maestroni S, Delucchi F, Zheng H, Ferreira-Martins J, Ogorek B, D'Amario D, Bauer M, Zerbini G, Rota M, Hosoda T, Liao R, Anversa P, Kajstura J, Leri A, Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart. Circ Res. 2010 Aug 6;107(3):429-41
1J:175538 Vega-Hernandez M, Kovacs A, De Langhe S, Ornitz DM, FGF10/FGFR2b signaling is essential for cardiac fibroblast development and growth of the myocardium. Development. 2011 Aug;138(15):3331-40
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1J:186606 Whitman SA, Cover C, Yu L, Nelson DL, Zarnescu DC, Gregorio CC, Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle. Circ Res. 2011 Jul 22;109(3):262-71
1*J:45489 Zabludoff SD, Csete M, Wagner R, Yu X, Wold BJ, p27Kip1 is expressed transiently in developing myotomes and enhances myogenesis. Cell Growth Differ. 1998 Jan;9(1):1-11
2J:206589 Zhao C, Guo H, Li J, Myint T, Pittman W, Yang L, Zhong W, Schwartz RJ, Schwarz JJ, Singer HA, Tallquist MD, Wu M, Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation. Development. 2014 Jan;141(2):281-95
2J:56270 Zhou Q, Ruiz-Lozano P, Martone ME, Chen J, Cypher, a striated muscle-restricted PDZ and LIM domain-containing protein, binds to alpha-actinin-2 and protein kinase C. J Biol Chem. 1999 Jul 9;274(28):19807-13

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