Gene Expression Literature Summary

• Symbol: Gip
• Name: gastric inhibitory polypeptide
• ID: MGI:107504

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9	E9.5	E11	E11.5	E13	E14.5	E15.5	E16	E16.5	E18	E18.5	E19.5	P
Immunohistochemistry (section)		1		1		1	1		3		5		6
In situ RNA (section)													1
RT-PCR	1	1	1		1			1		2	1	1	4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gip  gastric inhibitory polypeptide   (Synonyms: glucose-dependent insulinotropic polypeptide)
Results	Reference
1	J:228228 Bonnavion R, Teinturier R, Jaafar R, Ripoche D, Leteurtre E, Chen YJ, Rehfeld JF, Lepinasse F, Hervieu V, Pattou F, Vantyghem MC, Scoazec JY, Bertolino P, Zhang CX, Islet Cells Serve as Cells of Origin of Pancreatic Gastrin-Positive Endocrine Tumors. Mol Cell Biol. 2015 Oct;35(19):3274-83
2	J:119565 Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV, Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression. Dev Biol. 2006 Oct 15;298(2):616-31
1	J:141800 Edfalk S, Steneberg P, Edlund H, Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion. Diabetes. 2008 Sep;57(9):2280-7
1	J:104617 Fujitani Y, Fujitani S, Boyer DF, Gannon M, Kawaguchi Y, Ray M, Shiota M, Stein RW, Magnuson MA, Wright CV, Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation. Genes Dev. 2006 Jan 15;20(2):253-66
2*	J:191140 Grigoryan M, Kedees MH, Guz Y, Teitelman G, Phenotype of entero-endocrine L cells becomes restricted during development. Dev Dyn. 2012 Dec;241(12):1986-92
1	J:59312 Jensen J, Pedersen EE, Galante P, Hald J, Heller RS, Ishibashi M, Kageyama R, Guillemot F, Serup P, Madsen OD, Control of endodermal endocrine development by Hes-1. Nat Genet. 2000 Jan;24(1):36-44
2*	J:105459 Jepeal LI, Fujitani Y, Boylan MO, Wilson CN, Wright CV, Wolfe MM, Cell-specific expression of glucose-dependent-insulinotropic polypeptide is regulated by the transcription factor PDX-1. Endocrinology. 2005 Jan;146(1):383-91
3	J:161480 Mellitzer G, Beucher A, Lobstein V, Michel P, Robine S, Kedinger M, Gradwohl G, Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival. J Clin Invest. 2010 May 3;120(5):1708-21
1	J:167091 Nyeng P, Bjerke MA, Norgaard GA, Qu X, Kobberup S, Jensen J, Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche. Dev Biol. 2011 Jan 1;349(1):20-34
1	J:209016 Piccand J, Meunier A, Merle C, Jia Z, Barnier JV, Gradwohl G, Pak3 promotes cell cycle exit and differentiation of beta-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice. Diabetes. 2014 Jan;63(1):203-15
2	J:292845 Piccand J, Vagne C, Blot F, Meunier A, Beucher A, Strasser P, Lund ML, Ghimire S, Nivlet L, Lapp C, Petersen N, Engelstoft MS, Thibault-Carpentier C, Keime C, Correa SJ, Schreiber V, Molina N, Schwartz TW, De Arcangelis A, Gradwohl G, Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production. Mol Metab. 2019 Nov;29:24-39
10*	J:169398 Prasadan K, Koizumi M, Tulachan S, Shiota C, Lath N, Paredes J, Guo P, El-Gohary Y, Malek M, Shah S, Gittes GK, The expression and function of glucose-dependent insulinotropic polypeptide in the embryonic mouse pancreas. Diabetes. 2011 Feb;60(2):548-54
2	J:236406 Takada Y, Fukuda A, Chiba T, Seno H, Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling. Development. 2016 Oct 1;143(19):3532-3539
1	J:121610 Vanhorenbeeck V, Jenny M, Cornut JF, Gradwohl G, Lemaigre FP, Rousseau GG, Jacquemin P, Role of the Onecut transcription factors in pancreas morphogenesis and in pancreatic and enteric endocrine differentiation. Dev Biol. 2007 May 15;305(2):685-94
1	J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94
1	J:336753 Zinina VV, Sauer M, Nigmatullina L, Kreim N, Soshnikova N, TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine. Cells. 2023 May 23;12(11)