Gene Expression Literature Summary

• Symbol: Plcb2
• Name: phospholipase C, beta 2
• ID: MGI:107465

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1	E11.5	E13.5	E14.5	E15.5	E16.5	E17	E17.5	E18	E18.5	P
Immunohistochemistry (section)				1		1	1	1	1	1	10
In situ RNA (section)			1	1	1		1			1	4
In situ RNA (whole mount)					1
In situ reporter (knock in)											1
RT-PCR	1	1									4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Plcb2  phospholipase C, beta 2   (Synonyms: B230205M18Rik)
Results	Reference
1	J:317564 Filis P, Kind PC, Spears N, Implantation failure in mice with a disruption in Phospholipase C beta 1 gene: lack of embryonic attachment, aberrant steroid hormone signalling and defective endocannabinoid metabolism. Mol Hum Reprod. 2013 May;19(5):290-301
1*	J:306226 Firulli BA, George RM, Harkin J, Toolan KP, Gao H, Liu Y, Zhang W, Field LJ, Liu Y, Shou W, Payne RM, Rubart-von der Lohe M, Firulli AB, HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure. Cardiovasc Res. 2020 Mar 1;116(3):605-618
2	J:316093 Golden EJ, Larson ED, Shechtman LA, Trahan GD, Gaillard D, Fellin TJ, Scott JK, Jones KL, Barlow LA, Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function. Elife. 2021 May 19;10:e64013
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:167080 Iwatsuki K, Nomura M, Shibata A, Ichikawa R, Enciso PL, Wang L, Takayanagi R, Torii K, Uneyama H, Generation and characterization of T1R2-LacZ knock-in mouse. Biochem Biophys Res Commun. 2010 Nov 19;402(3):495-9
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1*	J:217303 Koudelka J, Horn JM, Vatanashevanopakorn C, Minichiello L, Genetic dissection of TrkB activated signalling pathways required for specific aspects of the taste system. Neural Dev. 2014;9:21
1*	J:263255 Kusumakshi S, Voigt A, Hubner S, Hermans-Borgmeyer I, Ortalli A, Pyrski M, Dorr J, Zufall F, Flockerzi V, Meyerhof W, Montmayeur JP, Boehm U, A Binary Genetic Approach to Characterize TRPM5 Cells in Mice. Chem Senses. 2015 Jul;40(6):413-25
1*	J:128289 Li Y, Chandrakanthan V, Day ML, O'Neill C, Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo. Biol Reprod. 2007 Nov;77(5):813-21
2	J:335201 Ohmoto M, Jyotaki M, Yee KK, Matsumoto I, A Transcription Factor Etv1/Er81 Is Involved in the Differentiation of Sweet, Umami, and Sodium Taste Cells. eNeuro. 2023 Apr;10(4):ENEURO.0236-22.2023
5	J:149230 Ota MS, Kaneko Y, Kondo K, Ogishima S, Tanaka H, Eto K, Kondo T, Combined in silico and in vivo analyses reveal role of Hes1 in taste cell differentiation. PLoS Genet. 2009 Apr;5(4):e1000443
2*	J:209852 Prandi S, Bromke M, Hubner S, Voigt A, Boehm U, Meyerhof W, Behrens M, A subset of mouse colonic goblet cells expresses the bitter taste receptor Tas2r131. PLoS One. 2013;8(12):e82820
1	J:272514 Rios-Pilier J, Krimm RF, TrkB expression and dependence divides gustatory neurons into three subpopulations. Neural Dev. 2019 Jan 28;14(1):3
4	J:186296 Saqui-Salces M, Keeley TM, Grosse AS, Qiao XT, El-Zaatari M, Gumucio DL, Samuelson LC, Merchant JL, Gastric tuft cells express DCLK1 and are expanded in hyperplasia. Histochem Cell Biol. 2011 Aug;136(2):191-204
1	J:165447 Suzuki Y, Ikeda K, Kawakami K, Expression of Six1 and Six4 in mouse taste buds. J Mol Histol. 2010 Oct;41(4-5):205-14
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
4	J:48405 Watanabe M, Nakamura M, Sato K, Kano M, Simon MI, Inoue Y, Patterns of expression for the mRNA corresponding to the four isoforms of phospholipase Cbeta in mouse brain. Eur J Neurosci. 1998 Jun;10(6):2016-25
1	J:259982 Weng PL, Vinjamuri M, Ovitt CE, Ascl3 transcription factor marks a distinct progenitor lineage for non-neuronal support cells in the olfactory epithelium. Sci Rep. 2016 Dec 2;6:38199
1	J:226215 Yamaguchi T, Yamashita J, Ohmoto M, Aoude I, Ogura T, Luo W, Bachmanov AA, Lin W, Matsumoto I, Hirota J, Skn-1a/Pou2f3 is required for the generation of Trpm5-expressing microvillous cells in the mouse main olfactory epithelium. BMC Neurosci. 2014;15:13
1	J:320732 Yu W, Ishan M, Yao Y, Stice SL, Liu HX, SOX10-Cre-Labeled Cells Under the Tongue Epithelium Serve as Progenitors for Taste Bud Cells That Are Mainly Type III and Keratin 8-Low. Stem Cells Dev. 2020 May 15;29(10):638-647