Gene Expression Literature Summary

• Symbol: Fxr1
• Name: FMR1 autosomal homolog 1
• ID: MGI:104860

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E3	E3.5	E11.5	E12.5	E13.5	E14	E14.5	E15.5	E16.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)							1						1		1		2
In situ RNA (section)						1	1	1		1		1					2
Immunohistochemistry (whole mount)		1
Northern blot																	2
Western blot													1	1			5
RT-PCR	1	1	1	1	1	1		2	1	1	1	1	1	1			7
cDNA clones																1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Fxr1  FMR1 autosomal homolog 1   (Synonyms: 1110050J02Rik, 9530073J07Rik, Fxr1h, Fxr1p)
Results	Reference
6	J:30134 Coy JF, Sedlacek Z, Bachner D, Hameister H, Joos S, Lichter P, Delius H, Poustka A, Highly conserved 3' UTR and expression pattern of FXR1 points to a divergent gene regulation of FXR1 and FMR1. Hum Mol Genet. 1995 Dec;4(12):2209-18
4	J:276784 Estan MC, Fernandez-Nunez E, Zaki MS, Esteban MI, Donkervoort S, Hawkins C, Caparros-Martin JA, Saade D, Hu Y, Bolduc V, Chao KR, Nevado J, Lamuedra A, Largo R, Herrero-Beaumont G, Regadera J, Hernandez-Chico C, Tizzano EF, Martinez-Glez V, Carvajal JJ, Zong R, Nelson DL, Otaify GA, Temtamy S, Aglan M, Issa M, Bonnemann CG, Lapunzina P, Yoon G, Ruiz-Perez VL, Recessive mutations in muscle-specific isoforms of FXR1 cause congenital multi-minicore myopathy. Nat Commun. 2019 Feb 15;10(1):797
1	J:282329 Hildebrandt MR, Wang Y, Li L, Yasmin L, Glubrecht DD, Godbout R, Cytoplasmic aggregation of DDX1 in developing embryos: Early embryonic lethality associated with Ddx1 knockout. Dev Biol. 2019 Nov 15;455(2):420-433
4*	J:103915 Huot ME, Bisson N, Davidovic L, Mazroui R, Labelle Y, Moss T, Khandjian EW, The RNA-binding protein fragile X-related 1 regulates somite formation in Xenopus laevis. Mol Biol Cell. 2005 Sep;16(9):4350-61
3*	J:142671 Kalsotra A, Xiao X, Ward AJ, Castle JC, Johnson JM, Burge CB, Cooper TA, A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20333-8
5*	J:113222 Li XY, Cui XS, Kim NH, Transcription profile during maternal to zygotic transition in the mouse embryo. Reprod Fertil Dev. 2006;18(6):635-45
4*	J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
6	J:91191 Mientjes EJ, Willemsen R, Kirkpatrick LL, Nieuwenhuizen IM, Hoogeveen-Westerveld M, Verweij M, Reis S, Bardoni B, Hoogeveen AT, Oostra BA, Nelson DL, Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo. Hum Mol Genet. 2004 Jul 1;13(13):1291-302
3*	J:291328 Smith JA, Curry EG, Blue RE, Roden C, Dundon SER, Rodriguez-Vargas A, Jordan DC, Chen X, Lyons SM, Crutchley J, Anderson P, Horb ME, Gladfelter AS, Giudice J, FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells. J Cell Biol. 2020 Apr 6;219(4)
2*	J:228946 Wei N, Cheng Y, Wang Z, Liu Y, Luo C, Liu L, Chen L, Xie Z, Lu Y, Feng Y, SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing. Cell Rep. 2015 Nov 24;13(8):1647-57
2*	J:176126 Xu XL, Zong R, Li Z, Biswas MH, Fang Z, Nelson DL, Gao FB, FXR1P But Not FMRP Regulates the Levels of Mammalian Brain-Specific microRNA-9 and microRNA-124. J Neurosci. 2011 Sep 28;31(39):13705-9
4*	J:259125 Yang J, Hung LH, Licht T, Kostin S, Looso M, Khrameeva E, Bindereif A, Schneider A, Braun T, RBM24 is a major regulator of muscle-specific alternative splicing. Dev Cell. 2014 Oct 13;31(1):87-99