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Gene Expression Literature Summary
Symbol
Name
ID
Lep
leptin
MGI:104663

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E1.5 E2 E2.5 E3 E4 E11.5 E12.5 E13.5 E14.5 E15 E16 E16.5 E17 E18.5 E A
In situ protein (section) 1 1 1 1 2
In situ RNA (section) 1 1 2 2 2 2
In situ protein (whole mount) 1 1 2 2 1 2 1 2
Northern blot 1 1 5
Western blot 1 2
RT-PCR 1 1 1 2 1 1 3 3 6

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Lep  leptin  
Results  Reference
9J:45849 Antczak M, Van Blerkom J, Oocyte influences on early development: the regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo. Mol Hum Reprod. 1997 Dec;3(12):1067-86
1*J:77646 Chen SS, Chen JF, Johnson PF, Muppala V, Lee YH, C/EBPbeta, when expressed from the C/ebpalpha gene locus, can functionally replace C/EBPalpha in liver but not in adipose tissue. Mol Cell Biol. 2000 Oct;20(19):7292-9
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
6J:102703 Fujimoto N, Matsuo N, Sumiyoshi H, Yamaguchi K, Saikawa T, Yoshimatsu H, Yoshioka H, Adiponectin is expressed in the brown adipose tissue and surrounding immature tissues in mouse embryos. Biochim Biophys Acta. 2005 Oct 15;1731(1):1-12
1J:39356 Good DJ, Porter FD, Mahon KA, Parlow AF, Westphal H, Kirsch IR, Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene. Nat Genet. 1997 Apr;15(4):397-401
8J:43489 Hoggard N, Hunter L, Duncan JS, Williams LM, Trayhurn P, Mercer JG, Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):11073-8
15J:74085 Hoggard N, Hunter L, Lea RG, Trayhurn P, Mercer JG, Ontogeny of the expression of leptin and its receptor in the murine fetus and placenta. Br J Nutr. 2000 Mar;83(3):317-26
3J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20
1J:58222 Kubota N, Terauchi Y, Miki H, Tamemoto H, Yamauchi T, Komeda K, Satoh S, Nakano R, Ishii C, Sugiyama T, Eto K, Tsubamoto Y, Okuno A, Murakami K, Sekihara H, Hasegawa G, Naito M, Toyoshima Y, Tanaka S, Shiota K, Kitamura T, Fujita T, Ezaki O, Aizawa S, Kadowaki T, et al, PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol Cell. 1999 Oct;4(4):597-609
1*J:81894 Lee K, Villena JA, Moon YS, Kim KH, Lee S, Kang C, Sul HS, Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor-1 (Pref-1). J Clin Invest. 2003 Feb;111(4):453-61
6J:180919 Schulz LC, Roberts RM, Dynamic changes in leptin distribution in the progression from ovum to blastocyst of the pre-implantation mouse embryo. Reproduction. 2011 Jun;141(6):767-77
2*J:44213 Tomimatsu T, Yamaguchi M, Murakami T, Ogura K, Sakata M, Mitsuda N , Kanzaki T , Kurachi H , Irahara M , Miyake A , Shima K , Aono T , Murata Y, Increase of mouse leptin production by adipose tissue after midpregnancy: gestational profile of serum leptin concentration. Biochem Biophys Res Commun. 1997 Nov 7;240(1):213-5

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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory