About   Help   FAQ
Gene Expression Literature Summary
Rap guanine nucleotide exchange factor (GEF) 1

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E9.5 E10.5 E11 E11.5 E12.5 E13 E13.5 E14.5 E15 E15.5 E16.5 E17 P
Immunohistochemistry (section) 1 1 1 1
In situ RNA (section) 2 3 2
In situ RNA (whole mount) 1
In situ reporter (knock in) 1 2 2 1 1
Northern blot 1 1
Western blot 2
RT-PCR 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Rapgef1  Rap guanine nucleotide exchange factor (GEF) 1   (Synonyms: 4932418O06Rik, C3G, Grf2)
Results  Reference
1*J:90089 Ballif BA, Arnaud L, Arthur WT, Guris D, Imamoto A, Cooper JA, Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons. Curr Biol. 2004 Apr 6;14(7):606-10
1*J:224930 Cheerathodi M, Vincent JJ, Ballif BA, Quantitative comparison of CrkL-SH3 binding proteins from embryonic murine brain and liver: Implications for developmental signaling and the quantification of protein species variants in bottom-up proteomics. J Proteomics. 2015 Jul 1;125:104-11
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1J:226036 Maddala R, Nagendran T, Lang RA, Morozov A, Rao PV, Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. Dev Biol. 2015 Oct 1;406(1):74-91
4J:248896 Shah B, Lutter D, Bochenek ML, Kato K, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Adams RH, Puschel AW, C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development. PLoS One. 2016;11(4):e0154174
2J:137018 Voss AK, Britto JM, Dixon MP, Sheikh BN, Collin C, Tan SS, Thomas T, C3G regulates cortical neuron migration, preplate splitting and radial glial cell attachment. Development. 2008 Jun;135(12):2139-49
7*J:80219 Voss AK, Gruss P, Thomas T, The guanine nucleotide exchange factor C3G is necessary for the formation of focal adhesions and vascular maturation. Development. 2003 Jan;130(2):355-67
5J:119299 Voss AK, Krebs DL, Thomas T, C3G regulates the size of the cerebral cortex neural precursor population. EMBO J. 2006 Aug 9;25(15):3652-63
3J:187338 Yip YP, Thomas T, Voss AK, Yip JW, Migration of sympathetic preganglionic neurons in the spinal cord of a C3G-deficient mouse suggests that C3G acts in the reelin signaling pathway. J Comp Neurol. 2012 Oct 1;520(14):3194-202

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory