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Gene Expression Literature Summary
Symbol
Name
ID
Arhgef2
Rho/Rac guanine nucleotide exchange factor 2
MGI:103264

4 matching records from 4 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E11 E11.5 E12 E13 E14.5 E15 E17 E18 E19 P
Immunohistochemistry (section) 1
In situ RNA (section) 1 1 1
In situ RNA (whole mount) 1
Northern blot 1 1 1
Western blot 1 1 1 2 2 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Arhgef2  Rho/Rac guanine nucleotide exchange factor 2   (Synonyms: GEFH1, GEF-H1, Lbcl1, Lfc, LFP40, mKIAA0651, P40)
Results  Reference
7*J:161097 Gauthier-Fisher A, Lin DC, Greeve M, Kaplan DR, Rottapel R, Miller FD, Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells. Nat Neurosci. 2009 Jun;12(6):735-44
3*J:242973 Ravindran E, Hu H, Yuzwa SA, Hernandez-Miranda LR, Kraemer N, Ninnemann O, Musante L, Boltshauser E, Schindler D, Hubner A, Reinecker HC, Ropers HH, Birchmeier C, Miller FD, Wienker TF, Hubner C, Kaindl AM, Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation. PLoS Genet. 2017 Apr;13(4):e1006746
4*J:99758 Ryan XP, Alldritt J, Svenningsson P, Allen PB, Wu GY, Nairn AC, Greengard P, The Rho-Specific GEF Lfc Interacts with Neurabin and Spinophilin to Regulate Dendritic Spine Morphology. Neuron. 2005 Jul 7;47(1):85-100
4*J:84356 Yoshizawa M, Sone M, Matsuo N, Nagase T, Ohara O, Nabeshima Y, Hoshino M, Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain. Gene Expr Patterns. 2003 Jun;3(3):375-81

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory