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Gene Expression Literature Summary
Symbol
Name
ID
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
MGI:103067

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1 E2 E2.5 E3 E6.5 E7 E7.5 E8 E8.5 E10.5 E11.5 E12 E12.5 E13 E13.5 E14.5 E15.5 E16 E16.5 E17 E17.5 E A
In situ protein (section) 2 1 1 1 4 2 3 1 2 7
In situ RNA (section) 1 1 1 1 2 1 2 1 1 1 1 1 1 1 1
In situ RNA (whole mount) 1 1 1 1 2 1
Western blot 1 6
RT-PCR 1 1 1 1 1 1 5
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Atrx  alpha thalassemia/mental retardation syndrome X-linked homolog (human)   (Synonyms: 4833408C14Rik, DXHXS6677E, Hp1bp2, HP1-BP38, Rad54, XH2, Xnp)
Results  Reference
4J:171630 Bagheri-Fam S, Argentaro A, Svingen T, Combes AN, Sinclair AH, Koopman P, Harley VR, Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome. Hum Mol Genet. 2011 Jun 1;20(11):2213-24
5J:95953 Berube NG, Mangelsdorf M, Jagla M, Vanderluit J, Garrick D, Gibbons RJ, Higgs DR, Slack RS, Picketts DJ, The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis. J Clin Invest. 2005 Feb;115(2):258-67
5J:194052 Corbel C, Diabangouaya P, Gendrel AV, Chow JC, Heard E, Unusual chromatin status and organization of the inactive X chromosome in murine trophoblast giant cells. Development. 2013 Feb;140(4):861-72
2J:115836 Garrick D, Sharpe JA, Arkell R, Dobbie L, Smith AJ, Wood WG, Higgs DR, Gibbons RJ, Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues. PLoS Genet. 2006 Apr;2(4):e58
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
9J:173600 Huyhn K, Renfree MB, Graves JA, Pask AJ, ATRX has a critical and conserved role in mammalian sexual differentiation. BMC Dev Biol. 2011;11:39
6J:150959 Kalantry S, Purushothaman S, Bowen RB, Starmer J, Magnuson T, Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation. Nature. 2009 Jul 30;460(7255):647-51
3J:158584 Kernohan KD, Jiang Y, Tremblay DC, Bonvissuto AC, Eubanks JH, Mann MR, Berube NG, ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain. Dev Cell. 2010 Feb 16;18(2):191-202
1J:37212 Le Douarin B, Nielsen AL, Garnier JM, Ichinose H, Jeanmougin F, Losson R, Chambon P, A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. EMBO J. 1996 Dec 2;15(23):6701-15
5J:145002 Medina CF, Mazerolle C, Wang Y, Berube NG, Coupland S, Gibbons RJ, Wallace VA, Picketts DJ, Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome. Hum Mol Genet. 2009 Mar 1;18(5):966-77
4J:188393 Michod D, Bartesaghi S, Khelifi A, Bellodi C, Berliocchi L, Nicotera P, Salomoni P, Calcium-dependent dephosphorylation of the histone chaperone DAXX regulates H3.3 loading and transcription upon neuronal activation. Neuron. 2012 Apr 12;74(1):122-35
1J:185555 Mugford JW, Yee D, Magnuson T, Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation. Development. 2012 Jun;139(12):2130-8
1J:150963 Pavlinkova G, Salbaum JM, Kappen C, Maternal diabetes alters transcriptional programs in the developing embryo. BMC Genomics. 2009;10:274
4J:142359 Seah C, Levy MA, Jiang Y, Mokhtarzada S, Higgs DR, Gibbons RJ, Berube NG, Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. J Neurosci. 2008 Nov 19;28(47):12570-80
3J:203136 Solomon LA, Russell BA, Watson LA, Beier F, Berube NG, Targeted loss of the ATR-X syndrome protein in the limb mesenchyme of mice causes brachydactyly. Hum Mol Genet. 2013 Dec 15;22(24):5015-25
8*J:21528 Stayton CL, Dabovic B, Gulisano M, Gecz J, Broccoli V, Giovanazzi S, Bossolasco M, Monaco L, Rastan S, Boncinelli E, Bianchi ME, Cloning and characterization of a new human Xq13 gene, encoding a putative helicase. Hum Mol Genet. 1994 Nov;3(11):1957-64
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
4J:201463 Watson LA, Solomon LA, Li JR, Jiang Y, Edwards M, Shin-ya K, Beier F, Berube NG, Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span. J Clin Invest. 2013 May 1;123(5):2049-63

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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory