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Symbol Name ID |
Hmga2
high mobility group AT-hook 2 MGI:101761 |
| Age | E1.5 | E2 | E2.5 | E3 | E3.5 | E4.5 | E8 | E9.5 | E10.5 | E11.5 | E12.5 | E13 | E13.5 | E14.5 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18.5 | A |
| In situ protein (section) | 1 | 1 | 1 | 1 | 2 | ||||||||||||||||
| In situ RNA (section) | 1 | 4 | 2 | 1 | 3 | 8 | 1 | 1 | 2 | 3 | 3 | ||||||||||
| In situ RNA (whole mount) | 2 | 1 | 1 | 1 | 1 | ||||||||||||||||
| Northern blot | 3 | 3 | 4 | 3 | 3 | 3 | 2 | 2 | 2 | 3 | |||||||||||
| Western blot | 1 | 1 | 2 | 1 | 2 | 1 | 2 | ||||||||||||||
| RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 3 | 2 | 2 | 3 | 7 | |||||||
| cDNA clones | 1 | ||||||||||||||||||||
| Primer Extension | 1 |
| Hmga2 high mobility group AT-hook 2 (Synonyms: 9430083A20Rik, Hmgic, HMGI-C) | |
| Results | Reference |
| 2* | J:61493 Anand A, Chada K, In vivo modulation of Hmgic reduces obesity. Nat Genet. 2000 Apr;24(4):377-80 |
| 1* | J:91358 Brants JR, Ayoubi TA, Chada K, Marchal K, Van de Ven WJ, Petit MM, Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor HMGA2. FEBS Lett. 2004 Jul 2;569(1-3):277-83 |
| 3 | J:86348 Chau KY, Manfioletti G, Cheung-Chau KW, Fusco A, Dhomen N, Sowden JC, Sasabe T, Mukai S, Ono SJ, Derepression of HMGA2 gene expression in retinoblastoma is associated with cell proliferation. Mol Med. 2003 May-Aug;9(5-8):154-65 |
| 8* | J:118604 D'Armiento J, Imai K, Schiltz J, Kolesnekova N, Sternberg D, Benson K, Pardo A, Selman M, Smolarek T, Vundavalli M, Sonnet J, Szabolcs M, Chada K, Identification of the benign mesenchymal tumor gene HMGA2 in lymphangiomyomatosis. Cancer Res. 2007 Mar 1;67(5):1902-9 |
| 1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
| 1* | J:171409 GUDMAP: the GenitoUrinary Development Molecular Anatomy Project, http://www.gudmap.org. 2004; |
| 7* | J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85 |
| 5 | J:50762 Hirning-Folz U, Wilda M, Rippe V, Bullerdiek J, Hameister H, The expression pattern of the Hmgic gene during development. Genes Chromosomes Cancer. 1998 Dec;23(4):350-7 |
| 1* | J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99 |
| 2 | J:131828 Kobayashi T, Lu J, Cobb BS, Rodda SJ, McMahon AP, Schipani E, Merkenschlager M, Kronenberg HM, Dicer-dependent pathways regulate chondrocyte proliferation and differentiation. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1949-54 |
| 3 | J:112318 Lord-Grignon J, Abdouh M, Bernier G, Identification of genes expressed in retinal progenitor/stem cell colonies isolated from the ocular ciliary body of adult mice. Gene Expr Patterns. 2006 Oct 2;6(8):992-999 |
| 1* | J:86589 McClive PJ, Hurley TM, Sarraj MA, van den Bergen JA, Sinclair AH, Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad. Genesis. 2003 Oct;37(2):84-90 |
| 7 | J:144068 Nishino J, Kim I, Chada K, Morrison SJ, Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression. Cell. 2008 Oct 17;135(2):227-39 |
| 1 | J:142508 Ota M, Sasaki H, Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling. Development. 2008 Dec;135(24):4059-69 |
| 6 | J:95925 Park YK, Franklin JL, Settle SH, Levy SE, Chung E, Jeyakumar LH, Shyr Y, Washington MK, Whitehead RH, Aronow BJ, Coffey RJ, Gene expression profile analysis of mouse colon embryonic development. Genesis. 2005 Jan;41(1):1-12 |
| 4 | J:148026 Price KL, Woolf AS, Long DA, Unraveling the genetic landscape of bladder development in mice. J Urol. 2009 May;181(5):2366-74 |
| 3 | J:140867 Sanosaka T, Namihira M, Asano H, Kohyama J, Aisaki K, Igarashi K, Kanno J, Nakashima K, Identification of genes that restrict astrocyte differentiation of midgestational neural precursor cells. Neuroscience. 2008 Aug 26;155(3):780-8 |
| 1* | J:149737 Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ, The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511 |
| 10* | J:74341 Schiltz JF, Kesari K, Ashar HR, Chada K, Hmgi-c-independent Activation of MuRantes in Vivo. Cell Growth Differ. 2002 Jan;13(1):39-45 |
| 2* | J:147982 Sehic A, Khuu C, Risnes S, Osmundsen H, Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse. Eur J Oral Sci. 2009 Apr;117(2):93-104 |
| 1 | J:188109 Tan SL, Nishi M, Ohtsuka T, Matsui T, Takemoto K, Kamio-Miura A, Aburatani H, Shinkai Y, Kageyama R, Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Development. 2012 Oct;139(20):3806-16 |
| 3 | J:74949 Terskikh AV, Easterday MC, Li L, Hood L, Kornblum HI, Geschwind DH, Weissman IL, From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs. Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7934-9 |
| 4 | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
| 3* | J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48 |
| 11 | J:28571 Zhou X, Benson KF, Ashar HR, Chada K, Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C [see comments]. Nature. 1995 Aug 31;376(6543):771-4 |
| 16* | J:36508 Zhou X, Benson KF, Przybysz K, Liu J, Hou Y, Cherath L, Chada K, Genomic structure and expression of the murine Hmgi-c gene. Nucleic Acids Res. 1996 Oct 15;24(20):4071-7 |
| 2 | J:193135 Zong Y, Huang J, Sankarasharma D, Morikawa T, Fukayama M, Epstein JI, Chada KK, Witte ON, Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer via paracrine Wnt signaling. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):E3395-404 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/05/2013 MGI 5.13 |
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