Go Annotations as Summary Text (Tabular View) (GO Graph)

GO curators for mouse genes have assigned the following annotations to the gene product of mt-Atp6. (This text reflects annotations as of Tuesday, May 21, 2013.) MGI curation of this mouse gene is considered complete, including annotations derived from the biomedical literature as of May 23, 2008. If you know of any additional information regarding this mouse gene please let us know. Please supply mouse gene symbol and a PubMed ID.

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Summary text based on GO annotations supported by experimental evidence in mouse

• Researchers have inferred from direct assay, that the gene product of mt-Atp6
  • is located in the following cellular components:
    • mitochondrion ^[1]

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Summary text based on GO annotations supported by structural data

• mt-Atp6 encodes a protein or proteins that contain the following InterPro domains: ATPase, F0 complex, subunit A, ATPase, F0 complex, subunit A, active site, indicating that the gene product:
  • participates in the following biological processes:
    • ATP synthesis coupled proton transport
  • performs the following molecular functions:
    • hydrogen ion transmembrane transporter activity
  • is located in the following cellular components:
    • proton-transporting ATP synthase complex, coupling factor F(o)

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Summary text for additional MGI annotations

• Automated translation to GO terms of SwissProt keywords that describe mt-Atp6 indicates that it:
  • participates in the following biological processes:
    • ATP biosynthetic process
    • ion transport
    • proton transport
    • transport
  • performs the following molecular functions:
    • hydrolase activity
  • is located in the following cellular components:
    • integral to membrane
    • membrane
    • mitochondrial inner membrane
    • proton-transporting ATP synthase complex, coupling factor F(o)

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References

1. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell, 134:112-23. (PubMed:18614015)

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Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

ISO Inferred from sequence orthology

ISA Inferred from sequence alignment

ISM Inferred from sequence model

NAS Non-traceable author statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

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