Automated description from the Alliance of Genome Resources (Release 5.2.2)
Enables heparin binding activity. Predicted to be involved in several processes, including neuron projection development; positive regulation of cell migration; and positive regulation of cell population proliferation. Predicted to act upstream of or within cell adhesion. Located in basement membrane. Part of laminin-5 complex. Is expressed in several structures, including alimentary system; basement membrane; central nervous system; genitourinary system; and skin. Used to study junctional epidermolysis bullosa Herlitz type and junctional epidermolysis bullosa non-Herlitz type. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa and lung small cell carcinoma. Orthologous to human LAMC2 (laminin subunit gamma 2).