Automated description from the Alliance of Genome Resources
Predicted to have extracellular matrix structural constituent and signaling receptor binding activity. Involved in axon guidance and positive regulation of cholinergic synaptic transmission. Localizes to several cellular components, including the neuromuscular junction; sarcolemma; and synaptic cleft. Used to study congenital merosin-deficient muscular dystrophy 1A. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy; congenital merosin-deficient muscular dystrophy 1A; muscular dystrophy; and myopia. Is expressed in several structures, including alimentary system; metanephros; musculature; nervous system; and skin. Orthologous to human LAMA2 (laminin subunit alpha 2).