Automated description from the Alliance of Genome Resources (Release 4.0)
Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in circulatory system development; response to retinoic acid; and tissue remodeling. Acts upstream of or within several processes, including negative regulation of angiogenesis; plasma membrane fusion; and vasculature development. Located in plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; extraembryonic component; genitourinary system; and hemolymphoid system gland. Orthologous to human TIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1).