Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and transcription factor binding activity. Involved in several processes, including animal organ development; positive regulation of cell differentiation; and regulation of transcription, DNA-templated. Localizes to the cytoplasm; nuclear chromatin; and transcription factor complex. Used to study cleidocranial dysplasia and congenital hypothyroidism. Human ortholog(s) of this gene implicated in cleidocranial dysplasia. Orthologous to human RUNX2 (RUNX family transcription factor 2).