Automated description from the Alliance of Genome Resources
Exhibits protease binding activity; ryanodine-sensitive calcium-release channel activity; and voltage-gated calcium channel activity. Involved in several processes, including animal organ development; cellular response to caffeine; and release of sequestered calcium ion into cytosol by sarcoplasmic reticulum. Localizes to the T-tubule; endoplasmic reticulum; and junctional membrane complex. Used to study central core myopathy and malignant hyperthermia. Human ortholog(s) of this gene implicated in central core myopathy and malignant hyperthermia. Orthologous to human RYR1 (ryanodine receptor 1).