Automated description from the Alliance of Genome Resources
Exhibits ATP binding activity; phosphotyrosine residue binding activity; and protein tyrosine kinase activity. Involved in several processes, including T cell selection; cellular protein modification process; and positive regulation of alpha-beta T cell activation. Localizes to the cell-cell junction; cytosol; and immunological synapse. Predicted to colocalize with the membrane raft. Used to study rheumatoid arthritis. Human ortholog(s) of this gene implicated in primary immunodeficiency disease and severe combined immunodeficiency. Orthologous to human ZAP70 (zeta chain of T cell receptor associated protein kinase 70).