Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including amyloid-beta binding activity; identical protein binding activity; and transmembrane signaling receptor activity. Involved in several processes, including modulation of chemical synaptic transmission; negative regulation of intracellular signal transduction; and plasma membrane bounded cell projection organization. Acts upstream of or within several processes, including neuron projection morphogenesis; optic nerve morphogenesis; and regulation of neurogenesis. Located in several cellular components, including axon; dendrite; and neuronal cell body. Is active in glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and synaptic membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; neural ectoderm; and sensory organ. Human ortholog(s) of this gene implicated in blood platelet disease. Orthologous to human EPHB2 (EPH receptor B2).