Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables cholesterol transfer activity; phospholipid transporter activity; and protein transmembrane transporter activity. Involved in several processes, including cellular response to lipid; positive regulation of cholesterol efflux; and protein transport. Acts upstream of or within several processes, including cholesterol metabolic process; lipid transport; and phagocytosis, engulfment. Located in Golgi apparatus and external side of plasma membrane. Is expressed in several structures, including alimentary system; connective tissue; genitourinary system; liver and biliary system; and nervous system. Used to study Tangier disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hypolipoproteinemia (multiple); obesity; and type 2 diabetes mellitus. Orthologous to human ABCA1 (ATP binding cassette subfamily A member 1).