Automated description from the Alliance of Genome Resources
Exhibits anion transmembrane transporter activity; cholesterol transfer activity; and phospholipid transporter activity. Involved in several processes, including cellular response to lipid; lipid transport; and positive regulation of cholesterol efflux. Localizes to the Golgi apparatus; external side of plasma membrane; and integral component of plasma membrane. Used to study Tangier disease. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; familial hypercholesterolemia; hypolipoproteinemia (multiple); obesity; and type 2 diabetes mellitus. Orthologous to human ABCA1 (ATP binding cassette subfamily A member 1).