Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits steroid binding activity. Involved in several processes, including cellular sodium ion homeostasis; excretion; and regulation of synaptic vesicle exocytosis. Localizes to GABA-ergic synapse and glutamatergic synapse. Is expressed in several structures, including central nervous system and genitourinary system. Used to study autosomal dominant pseudohypoaldosteronism type 1. Human ortholog(s) of this gene implicated in autosomal dominant pseudohypoaldosteronism type 1 and pseudohypoaldosteronism. Orthologous to human NR3C2 (nuclear receptor subfamily 3 group C member 2).