Automated description from the Alliance of Genome Resources (Release 5.2.2)
Enables melanocyte-stimulating hormone receptor activity. Involved in positive regulation of bone resorption; regulation of eating behavior; and response to melanocyte-stimulating hormone. Acts upstream of or within several processes, including feeding behavior; insulin secretion; and response to insulin. Predicted to be located in nucleus. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including axial skeleton; nervous system; and thyroid gland. Used to study fatty liver disease; non-alcoholic steatohepatitis; and obesity. Human ortholog(s) of this gene implicated in morbid obesity and obesity. Orthologous to human MC4R (melanocortin 4 receptor).