Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II distal enhancer sequence-specific DNA binding activity; and cholesterol binding activity. Involved in several processes, including neurogenesis; regulation of organelle organization; and regulation of transcription by RNA polymerase II. Localizes to the endoplasmic reticulum membrane; nucleus; and protein-containing complex. Used to study hepatocellular carcinoma and type 2 diabetes mellitus. Orthologous to human NFE2L1 (nuclear factor, erythroid 2 like 1).