About   Help   FAQ
Gene Ontology Classifications
Symbol
Name
ID
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
MGI:99400

Go Annotations as Summary Text (Tabular View) (GO Graph)

GO curators for mouse genes have assigned the following annotations to the gene product of Atp7a. (This text reflects annotations as of Tuesday, July 8, 2014.)
Summary from NCBI RefSeq


[Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. [provided by RefSeq, Aug 2013]
Summary text based on GO annotations supported by experimental evidence in mouse
Summary text based on GO annotations supported by experimental evidence in other organisms
Summary text based on GO annotations supported by structural data
Summary text for additional MGI annotations
References
  1. . () , :. (PubMed:)
  2. . () , :. (PubMed:)
  3. . () , :. (PubMed:)
  4. . () , :. (PubMed:)
  5. . () , :. (PubMed:)
  6. . () , :. (PubMed:)
  7. . () , :. (PubMed:)
  8. . () , :. (PubMed:)
  9. . () , :. (PubMed:)
  10. . () , :. (PubMed:)
  11. . () , :. (PubMed:)
  12. . () , :. (PubMed:)
  13. . () , :. (PubMed:)
  14. . () , :. (PubMed:)
  15. . () , :. (PubMed:)
  16. . () , :. (PubMed:)
  17. . () , :. (PubMed:)
  18. . () , :. (PubMed:)
  19. . () , :. (PubMed:)
  20. . () , :. (PubMed:)
  21. . () , :. (PubMed:)
  22. . () , :. (PubMed:)
  23. . () , :. (PubMed:)
  24. . () , :. (PubMed:)
  25. . () , :. (PubMed:)
  26. . () , :. (PubMed:)
  27. . () , :. (PubMed:)
  28. . () , :. (PubMed:)
  29. . () , :. (PubMed:)
  30. . () , :. (PubMed:)
  31. . () , :. (PubMed:)
  32. . () , :. (PubMed:)
  33. . () , :. (PubMed:)
  34. . () , :. (PubMed:)
  35. . () , :. (PubMed:)
  36. . () , :. (PubMed:)
  37. . () , :. (PubMed:)
  38. . () , :. (PubMed:)
  39. . () , :. (PubMed:)
  40. . () , :. (PubMed:)
  41. . () , :. (PubMed:)
  42. . () , :. (PubMed:)
  43. . () , :. (PubMed:)
  44. . () , :. (PubMed:)
  45. . () , :. (PubMed:)
  46. . () , :. (PubMed:)
  47. . () , :. (PubMed:)
  48. . () , :. (PubMed:)
  49. . () , :. (PubMed:)
  50. . () , :. (PubMed:)
  51. . () , :. (PubMed:)
  52. . () , :. (PubMed:)
  53. . () , :. (PubMed:)
  54. . () , :. (PubMed:)
  55. . () , :. (PubMed:)
  56. . () , :. (PubMed:)
  57. . () , :. (PubMed:)
  58. . () , :. (PubMed:)
  59. . () , :. (PubMed:)
  60. . () , :. (PubMed:)
  61. . () , :. (PubMed:)
  62. . () , :. (PubMed:)
  63. . () , :. (PubMed:)



Go Annotations in Tabular Form (Text View) (GO Graph)

 
 


Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  ISS Inferred from sequence or structural similarity
  ISO Inferred from sequence orthology
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  NAS Non-traceable author statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/23/2014
MGI 5.19
The Jackson Laboratory