Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables 14-3-3 protein binding activity; RNA polymerase binding activity; and mRNA 3'-UTR AU-rich region binding activity. Involved in several processes, including cellular response to tumor necrosis factor; p38MAPK cascade; and regulation of gene expression. Acts upstream of or within intracellular signal transduction; negative regulation of cell differentiation; and regulation of RNA metabolic process. Located in cytosol and nucleus. Part of CCR4-NOT complex and ribonucleoprotein complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and hemolymphoid system gland. Used to study rheumatoid arthritis. Orthologous to human ZFP36 (ZFP36 ring finger protein).