Automated description from the Alliance of Genome Resources
Predicted to have damaged DNA binding activity; protein domain specific binding activity; and protein homodimerization activity. Involved in several processes, including growth; intrinsic apoptotic signaling pathway in response to DNA damage; and positive regulation of transcription initiation from RNA polymerase II promoter. Localizes to the nucleus. Predicted to colocalize with the DNA replication factor A complex. Used to study xeroderma pigmentosum group A. Human ortholog(s) of this gene implicated in xeroderma pigmentosum and xeroderma pigmentosum group A. Is expressed in forelimb bud. Orthologous to human XPA (XPA, DNA damage recognition and repair factor).