About   Help   FAQ
Gene Ontology Classifications
Symbol
Name
ID
Xdh
xanthine dehydrogenase
MGI:98973

Go Annotations as Summary Text (Tabular View) (GO Graph)


Automated description from the Alliance of Genome Resources (Release 4.0)

Enables oxidoreductase activity, acting on CH or CH2 groups. Involved in allantoin metabolic process and purine-containing compound catabolic process. Acts upstream of or within iron-sulfur cluster assembly; lactation; and regulation of epithelial cell differentiation. Located in sarcoplasmic reticulum. Is active in cytosol. Is expressed in several structures, including adrenal gland; genitourinary system; intestine; liver; and lung. Human ortholog(s) of this gene implicated in several diseases, including Lesch-Nyhan syndrome; cardiovascular system disease (multiple); chronic kidney disease; hyperuricemia; and xanthinuria. Orthologous to human XDH (xanthine dehydrogenase).



Go Annotations in Tabular Form (Text View) (GO Graph)

Filter annotations by: Aspect  Category  Evidence 

 
 


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement

Filter

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/20/2021
MGI 6.17
The Jackson Laboratory