Automated description from the Alliance of Genome Resources
Exhibits xanthine dehydrogenase activity. Involved in lactation; oxidation-reduction process; and regulation of epithelial cell differentiation. Localizes to the sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in several diseases, including Lesch-Nyhan syndrome; cardiovascular system disease (multiple); chronic kidney disease; hyperuricemia; and xanthinuria. Is expressed in several structures, including adrenal gland; genitourinary system; intestine; liver; and lung. Orthologous to human XDH (xanthine dehydrogenase).