Automated description from the Alliance of Genome Resources
Predicted to have several functions, including chaperone binding activity; integrin binding activity; and protein homodimerization activity. Involved in animal organ development; cell-substrate adhesion; and platelet activation. Localizes to the external side of plasma membrane. Used to study von Willebrand's disease 2. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; atrial fibrillation; end stage renal failure; essential thrombocythemia; and inherited blood coagulation disease (multiple). Is expressed in several structures, including cardiovascular system; extraembryonic component; female reproductive system; leptomeninges; and renal vasculature. Orthologous to human VWF (von Willebrand factor).