Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have several functions, including chaperone binding activity; identical protein binding activity; and integrin binding activity. Involved in animal organ development; cell-substrate adhesion; and platelet activation. Localizes to external side of plasma membrane. Is expressed in several structures, including cardiovascular system; extraembryonic component; female reproductive system; leptomeninges; and renal vasculature. Used to study von Willebrand's disease 2. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; atrial fibrillation; end stage renal disease; essential thrombocythemia; and inherited blood coagulation disease (multiple). Orthologous to human VWF (von Willebrand factor).