Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables guanyl-nucleotide exchange factor activity and phosphorylation-dependent protein binding activity. Acts upstream of or within several processes, including integrin-mediated signaling pathway; neutrophil chemotaxis; and positive regulation of natural killer cell mediated cytotoxicity. Located in cell-cell junction. Is expressed in several structures, including extraembryonic component; hemolymphoid system; liver; pancreas; and trunk mesenchyme. Orthologous to human VAV1 (vav guanine nucleotide exchange factor 1).