Automated description from the Alliance of Genome Resources
Exhibits Rac guanyl-nucleotide exchange factor activity. Involved in several processes, including integrin-mediated signaling pathway; neutrophil chemotaxis; and positive regulation of natural killer cell mediated cytotoxicity. Localizes to the cell-cell junction. Is expressed in several structures, including dorsal aorta; extraembryonic component; hemolymphoid system; pancreas; and reproductive system. Orthologous to human VAV1 (vav guanine nucleotide exchange factor 1).